THE INFLUENCE OF PHYSICAL FACTORS ON BIOPHYSICAL PARAMETERS OF CELLS
Main researcher
: ŠOLIĆ, FRANJO (47785) Assistants
STIPČIĆ-ŠOLIĆ, NEDA (64624)
ŽAUHAR, GORDANA (142294)
MARIĆ, GORDANA (133621)
Type of research: basic Duration from: 04/30/91. to 04/30/94. Papers on project (total): 6
Institution name: Medicinski fakultet, Rijeka (62) Department/Institute: Department of physics Address: Braće Branchetta 20 City: 51000 - Rijeka, Croatia
Communication
Phone: 385 (0)51/ 22 74 69
Fax: 385 (0)51/ 51 49 15
E-mail: Franjo.Solic@mamed.medri.hr
Summary: The purpose of this project is the investigation of the
influence of the combined effect of no ionizing and ionizing radiation,
temperature, electric and magnetic fields, and ultrasound on the
fundamental biophysical parameters of the biological systems (bioelectric
potentials, ionic currents, bioluminiscence, free radicals). From results
obtained, the conclusions are to be made about applicability of combined
effects on stimulation or inhibition of viability of cells.
Research goals: The purpose of this project is the investigation
of the influence of the combined effect of no ionizing and ionizing
radiation, temperature, electric and magnetic fields, and ultrasound on
the fundamental biophysical parameters of the biological systems
(bioelectric potentials, ionic currents,bioluminiscence, free radicals).
From the results obtained, the conclusions are to be made about
applicability of combined effects on stimulation or inhibition of
viability of cells. The influence of the laser-radiation on the Nitella
resting potentials were established. The irradiation in dark caused
repolarisation of the cell membrane, proportional to the radiation
intensity. The laser-irradiation combined with white and red light
provoked depolarisation of the membrane. The beginning and the magnitude
of depolarisation are in dependance with the laser beam intensity. This
phenomenon is being closely investigated. All the investigations have
not been completed, and thereforethe results are not completely
elaborated.
COOPERATION - INSTITUTIONS
Name of institution
: INSTITUT "JOŽEF ŠTEFAN" LJUBLJANA, Jamova
39 Type of institution: State institute Type of cooperation: Other City: 61000 - Ljubljana, Slovenija
Name of institution
: ZAVOD ZA MEDICINSKU FIZIKU, GINEKOLOŠKI
CENTAR ZAGREB, Petrova 13 Type of institution: Institution whose primary activities ar Type of cooperation: Other City: 10000 - Zagreb, Croatia Other information about the project.