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Papers quoted in Current Contents on project 3-01-041
Quoted papers: 8
Other papers: 46
Total: 54
Title: Tunica propria of seminiferous tubules in human fetal
testis - an immunological and stereological study.
- Authors:
- Ježek, Davor (171511)
- Kos, Marina
- Hittmair, Anton
- Rogatsch, Hermann
Journal: Anatomy and Embryology
Year: 1995
Number of references: 48
Language: engleski
Summary: Testicular peritubular cells are located in the tunica
propria of seminiferous tubules. These cells, significantly contribution to
the basal membrane of seminiferous epithelium, have been studied in a
number of species. However, there is a lack of data on the development of
the tunica propria in the human testis. The aim of our survey was to
investigate the characteristics of the tunica propria and, in particular,
peritubular cells in the fetal human testes by immunological and
stereological methods. Therefore, testes (14-19 weeks of gestation, N=45)
were dissected and fixed in a 4% buffered paraformaldehyde. Several parts
of each testis were embedded in paraffin and processed for
immunohistochemical and stereological analysis. All investigated testes
have showed seminiferous tubules in a process of development and
differentiation. Morphologically, peritubular cells in the tunica propria
can be divided into two types: fibroblast-like (FL) and myoid-like (ML)
type (cells which much resemble to mature myoid cells). By
immunohistochemistry, the both, FL and ML cells, are strongly positive for
the intermediate filament desmin, but negative to alpha-smooth actin. While
FL cells intensively express Ki-67 demonstrating proliferative activity, ML
cells are found to be negative. The basement membrane of seminiferous
tubules as well as the blood vessels of the interstitium show strong
positivity to collagen IV and laminin. Concerning the correlation between
the appearance of the investigated antigens with the gestational age, all
antigens have been expressed (in the manner described above) already in
14th week of gestation. The stereological analysis of the number (Nv),
surface (Sv) and volume (Vv) of peritubular cells indicates a pulsatile
development of these cells in the tunica propria of the human fetal testis.
While mentioned stereological variables determined for FL cells show a
gradual decrease, the same variables determined for ML cells demonstrate a
successive increase. It appears that the tunica propria of the fetal human
testes shares much of the properties previously discovered in rodens.
Keywords: testis, myoid cells, fetus, human
Title: Complex pattern of intermediate filament expression of
Sertoli cells in fetal testes and in testicular disease.
- Authors:
- Rogatsch, Hermann
- Ježek, Davor (171511)
- Hittmair, Anton
- Mikuz, Gregor
- Feichtinger, H.
Journal: Virchows Archieve Pathology
Year: 1995
Language: engleski
Title: Effects of orchiectomy on the rat parotid gland - an
ultrastructural and stereologica study.
- Authors:
- Ježek, Davor (171511)
- Banek, Ljerka (76706)
- Banek, Tomislav
Journal: Acta Anatomica (Basel)
Year: 1996
Number of references: 38
Language: engleski
Summary: The relation of the testis and testosterone with the
structure and function of the mammalian parotid gland has been so far
poorly investigated. Hence, our study deals with the morphology of the rat
parotid gland and its changes after orchiectomy and testosterone
supstitution. The glands of control and experimental animals
(orchiectomized and orchiectomized with testosterone supstitution) have
been analyzed by electron microscopy and stereology. In orchiectomized
animals after 30-60 days of castration, a significant reduction of the
volume of the acini and the duct system as well as a significant increase
of the connective tissue volume per mm3 of the gland has been noted
(P<0.01). The volume and length of intercalated and striated ducts per mm3
of the parotid tissue in orchiectomized animals is significantly reduced
45-60 days after the testis removal (P<0.001). Excretory ducts seem to be
unaffected by orchiectomy (P>0.05). The structure of the rat parotid acini
is also changed by castration indicating an inversion of the acinar cells
activity. In controls, the volume of acinar cells with wide cisternae of
rough endoplasmic reticulum (RER) is 3 times bigger than the volume of
acinar cells with regular and narrow cisternae of RER. After orchiectomy,
the volume of acinar cells with wide cisternae of RER is significantly
decreased, while the volume of acinar cells with regular and narrow
cisternae of RER is significantly increased (60th day - P<0.001).
Exogenously given testosterone can prevent or alleviate mentioned effects
of orchiectomy on the gland. It is concluded that orchiectomy affects the
rat parotid gland, demonstrating the existence of the interaction between
the testis the mammalian parotid gland.
Keywords: parotid gland, rat, orchiectomy, testosterone, stereology
Title: Seminiferous tubules curvature in damaged testes.
- Authors:
- Banek, Ljerka (76706)
- Ježek, Davor (171511)
- Kablar, Boris
- Percač, Sanja
Journal: Journal of Clinical Anatomy
Number: 3
Volume: 15
Year: 1993
Pages: from 231 to 231
Language: engleski
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