SVIBOR - Project code: 3-01-085

MINISTRY OF SCIENCE AND TECHNOLOGY

Strossmayerov trg 4, HR - 10000 ZAGREB
tel.: +385 1 459 44 44, fax: +385 1 459 44 69
E-mail: ured@znanost.hr

SVIBOR

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Project code: 3-01-085


Changes in maternal, placental and fetal circulation in abnormal pregnancies


Main researcher: MILKOVIĆ-LATIN, VIŠNJA (31651)


Assistants
Type of research: applied
Duration from: 01/01/95.
Papers on project (total): 53
Papers on project quoted in Current Contents: 8
Institution name: Medicinski fakultet, Zagreb (108)
Department/Institute: Department of Obstetrics and Gynecology, University of Zagreb Perinatal center
Address: Petrova 13
City: 10000 - Zagreb, Croatia
Communication
Phone: 385 (0)1 579 251
Fax: 385 (0)1 579 248
Summary: The effects of pulsed Doppler ultrasound on microbial systems, glycoprotein and ganglioside changes in human trophoblast as well as releasing of placental hormones - HCG, HPL and estriol in the culture tissue. Blood flow in corpus luteum in normal and abnormal pregnancies is investigated. The localisation of osteogenic protein 1 in human trophoblast and embryonic tissue is established. Blood flow in maternal, placental and fetal vessels in normal and abnormal (diabetic, hypertensive and IUGR) advanced pregnancies is evaluated. The changes in hystological findings are correlated with blood flow changes. The investigation of blood flow in yellow sac and viteline duct and changes in spiral arteries in normal and abnormal pregnancies is still in progress.

Keywords: pulsed Doppler ultrasound, safety microbial systems, glycoproteins, gangliosides, placental hormones, corpus luteum, normal, abnormal pregnancy, yolk sac, spiral arteries

Research goals: The genotoxic effects of pulsed Doppler ultrasound in culture tissue were investigated in the first part. In the second part the changes of blood flow in early and late normal and abnormal pregnancies which could be a cause of spontaneous abortion or indication of fetal hypoxia were observed.

COOPERATION - PROJECTS


  1. Name of project: The role of basement membrane in cartilage and bone differentiation and repair
    Name of institution: Medicinski fakultet
    City: 10000 - Zagreb, Croatia

COOPERATION - INSTITUTIONS


  1. Name of institution: Medicinski fakultet
    Type of institution: University/Faculty
    Type of cooperation: Joint project
    City: 10000 - Zagreb, Croatia

  2. Name of institution: Zavod za anatomiju Medicinskog fakulteta u Zagrebu
    Type of institution: University/Faculty
    Type of cooperation: Joint project
    City: 10000 - Zagreb, Croatia

  3. Name of institution: Institut za organsku kemiju i biokemiju Medicinskog fakulteta u Zagrebu
    Type of institution: University/Faculty
    Type of cooperation: Joint publishing of scientific papers
    City: 10000 - Zagreb, Croatia

  4. Name of institution: Institut za medicinsku biokemiju Fakulteta za farmaciju i biokemiju Sveučilišta u Zagrebu
    Type of institution: University/Faculty
    Type of cooperation: Joint publishing of scientific papers
    City: 10000 - Zagreb, Croatia

  5. Name of institution: Institut za kemiju Sveučilišta u Mainzu
    Type of institution: University/Faculty
    Type of cooperation: Joint publishing of scientific papers
    City: Mainz, Njemačka

  6. Name of institution: Prehrambeno-biotehnološki fakultet Sveučilišta u Zagrebu
    Type of institution: University/Faculty
    Type of cooperation: Joint publishing of scientific papers
    City: 10000 - Zagreb, Croatia
Other information about the project.
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Last update: 10/18/95
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