- Type of paper
: Paper in journal
Title:
- Authors:
- Dorić, Miljenko (85032)
- Gligora, Mario (75503)
Journal: Folia Biologica (Praha)
Number: 2
ISSN: 0015-5500
Volume: 37
Year: 1991
Pages: from 131 to 133
Number of references: 5
Language: engleski
Summary: In medical practice aryloxycarbonic acid derivatives have
beensolely used in the treatment of hyperlipidemia. Recently wepatented the
use of some of these derivatives in the treatment ofdermatological
diseases. Further analyses showed that thesesubstances stimulated various
cells of mesodermal originincluding lymphocytes, the principal cells of the
immune system.Depending on the concentration some derivatives
ofaryloxycarbonic acid stimulated or suppressed the proliferativeresponse
of lymphocytes, pointing to the possible use of thesedrugs as
immunomodulators in clinical practice as well.
Keywords: aryloxycarbonic acid derivatives, phytohaemagglutinin
- Type of paper
: Paper in journal
Title:
- Authors:
- Šamanić, Vinko (107951)
- Kelenc, Darko
Journal: Acta Facultatis Medicae Fluminensis
Number: 3
ISSN: 0065-1206
Volume: 16
Year: 1991
Pages: from 113 to 118
Number of references: 21
Language: engleski
Summary: Within a collection of 2.437 differently originating
consecutivestool specimens, salmonellae were revealed in 109 i.e 4.41%.
Ofthese, not more than 34 i.e. 1.37% could be confirmed by bothmethods
(direct immunofluorescence, plus culturing), while even75 i.e. 3.03% could
solely be detected by directimmunofluorescence (cultivation failed) and
were referred to as"non-cultivable".
Keywords: immunofluorescence, Salmonella, non-cultivable strains
- Type of paper
: Paper in journal
Title:
- Authors:
- Mahulja-Stamenković, Vesna (194792)
- Beleznay, Oton (2974)
- Stamenković, Mile (143341)
- Samardžija, Radojka
- Makiš, Janko (27500)
Journal: Zentralblatt fur Gynakologie
ISSN: 0044-4197
Volume: 115
Year: 1993
Pages: from 33 to 35
Number of references: 7
Language: engleski
Summary: Total of 321 preterm/term newborns delivered in normal
singletonvaginal deliveries was studied. Babies were divided into
twogroups. The first one includes 62 newborns with single, isolatedclinical
sign: stinking amniotic fluid or intrapartal maternalfebrility (>= 38C) or
duration of delivery > 12 hours. The secondone (control group) contained
259 newborns with no such a sign.In both groups the umbilical cord blood
IgG, IgM and IgAconcentrations were quantified by RID. The obtained results
didnot express significant differences in the mean IgG, IgM and
IgAumblilical cord blood concentrations between the two groups.
Keywords: IgG, IgM, IgA, umbilical cord blood, preterm and term pregnancies, stinking amniotic fluid, maternal febrility (>= 38C), duration of delivery (> 12 hours)
- Type of paper
: Paper in journal
Title:
- Authors:
- Makiš, Janko (27500)
- Dorić, Miljenko (85032)
Journal: Acta Facultatis Medicae Fluminensis
Number: 1
ISSN: 0065-1206
Volume: 18
Year: 1993
Pages: from 11 to 23
Number of references: 10
Language: engleski
Summary: A numerical diagnostic key for the identification
ofgram-negative fermentative bacteria is described. Unknown strainswere
inoculated into a routine biochemical set. Points wereassigned to positive
reactions and the score of thirteen testswas added up, after which the
identification of the strain wasobtained from the key. Final identification
using this numericalkey was obtained in 67.48% strains, while in the
remaining ones asmall number of additional biochemical test was required
todistinguish between strains giving the same score in the routineset of
biochemical tests.
Keywords: gram-negative bacteria, computer
- Type of paper
: Paper in journal
Title:
- Authors:
- Dorić, Miljenko (85032)
- Abram, Maja (133610)
- Rukavina, Tomislav (163264)
Journal: Folia Biologica (Praha)
ISSN: 0015-5500
Volume: 39
Year: 1993
Pages: from 162 to 165
Number of references: 5
Language: engleski
Summary: Antibiotics, in addition to killing or inhibiting the
growth ofmicroorganisms, may also affect the immune response in many
ways.Such effects may be clinically relevant especially when animpairment
of immunological functions is seen. This study wasdesigned to analyse the
influence of various groups ofantibiotics on the host defence system. We
also analysed theantimicrobial effectiveness of the same antibiotics on
over 2800bacterial strains isolated from our clinical material.Praliminary
finding show that a correlation exists between theeffect of antibiotics on
the immune response and the appearanceof resistance in bacteria to these
antibiotics.
Keywords: antibiotics, bacteria, immune response
- Type of paper
: Paper in proceedings
Title: Monitoring the effect of chemotherapeutics on immune
system
- Authors:
- Abram, Maja (133610)
- Rukavina, Tomislav (163264)
- Dorić, Miljenko (85032)
- Editors
- Petričević, Ivan
Proceedings title: Dijagnostički postupci u kliničkoj obradi infektoloških bolesnika
Language: hrvatski
Place: Zagreb
Year: 1993
Pages: from 151 to 153
Meeting: 1. Hrvatski stručno-znanstveni sastanak infektologa, mikrobiologa i epidemiologa
Held: from 05/21/92 to 05/22/92
Summary: Antibiotics, in addition to killing or inhibiting the
growth ofmicroorganisms may also affect immune response in many ways.
Sucheffects may be clinically relevant especially in the case wherean
impairment of immunological functions is seen. Therefore, wedecided to
study the influence of various groups of antibioticson the host defence
system by using different tests in vitro onhuman or animal cells and in
vivo on animal model. the resultswere compared with the results obtained in
analysing theantibiograms, i.e. the antimicrobial effectiveness of the
sameantibiotics.
Keywords: antibiotics, immune system
- Type of paper
: Paper in proceedings
Title: Identification of bacteria by means of a computer
- Authors:
- Vučković, Darinka (133680)
- Tićac, Brigita (163253)
- Makiš, Janko (27500)
- Editors
- Petričević, Ivan
Proceedings title: Dijagnostički postupci u kliničkoj obradi infektoloških bolesnika
Language: hrvatski
Place: Zagreb
Year: 1993
Pages: from 208 to 210
Meeting: 1. Hrvatski stručno-znanstveni sastanak infektologa, mikrobiologa i epidemiologa
Held: from 05/21/92 to 05/22/92
Summary: The numerical diagnostic keys for the identification
ofgram-negative fermentative and nonfermentative bacteria as wellas for
coagulase negative Staphylococci and other gram-positivecocci are
described. These keys permit the identification ofdifferent species and
their biochemical variants with highaccuracy. The proposed keys are
acceptable for routine work andmay be used by hand or can be accumulated by
computer as at ourDepartment.
Keywords: bacterium, numerical key, computer
- Type of paper
: Summary in proceedings
Title:
- Authors:
- Gligora, Mario (75503)
- Dorić, Miljenko (85032)
- Vranešić, D
- Sabolić, Josip (85436)
Proceedings title: Congres International d'Angiologie - Abstracts
Language: engleski
Place: Pariz, Francuska
Year: 1991
Pages: from 68 to 68
Meeting: International Congress on Angiology - ANGIO '91
Held: from 04/12/91 to 04/14/91
Summary: Patients with venous leg ulcer were treated with
aryloxycarbonicacid derivatives (ACA). The results were very encouraging.
In aseries of new tests we whowed that these supstances have
noantimicrobial activity in the used concentrations so that healingcan not
be argued to be potentiated through this mechanism.However, at the same
time we demonstrated that these supstancesstimulate regeneration of cells
and tissues of mesodermal originincluding the proliferative response of
peripheral bloodlymphocytes.
Keywords: aryloxycarbonic acid derivatives, ulcus cruris, immune response
- Type of paper
: Summary in proceedings
Title:
- Authors:
- Dorić, Miljenko (85032)
- Makiš, Janko (27500)
Proceedings title: 8th Mediterranean Congress of Chemotherapy - Abstracts
Language: engleski
Place: Atena, Grčka
Year: 1992
Pages: from 23 to 23
Meeting: 8th Mediterranean Congress of Chemotherapy
Held: from 05/24/92 to 05/29/92
Summary: Data were presented showing the frequency of pathogenes
isolatedduring nosocomial infections, as well as, the results
ofantimicrobial effectiveness testing. The most frequently isolatedspecies
belong to the genus Staphylococcus and gram-negativerods. Through the
mentioned period the antimicrobialsusceptibility of gram-positive bacteria
showed a marked increasein the number of resistant strains to
sulfamethoxazole, TMP-SMX,ceftriaxone and cefuroxime. Gram-negative
fermentative bacteriaare becoming significantly more resistant to
ampicillin andcarbenicillin and the nonfermentative to netilmicin,
ceftriaxoneand ceftazidime.
Keywords: bacteria, chemotherapeutics, nosocomial infections
- Type of paper
: Summary in proceedings
Title: Susceptibility of bacteria isolated from clinical samples
- Authors:
- Abram, Maja (133610)
- Vučković, Darinka (133680)
- Rukavina, Tomislav (163264)
- Makiš, Janko (27500)
- Dorić, Miljenko (85032)
- Editors
- Vučković, Darinka (133680)
- Žele-Starčević, Lidija
- Knežević, Predrag
Proceedings title: 3. Hrvatski kongres kliničke mikrobiologije - Knjiga sažetaka
Language: hrvatski
Place: Zagreb
Year: 1993
Pages: from 12 to 12
Meeting: 3. Hrvatski kongres kliničke mikrobiologije
Held: from 10/13/93 to 10/15/93
- Type of paper
: Summary in proceedings
Title: Isolation of gram-positive Cocci from material obtained
from the Orthopedic Clinic in Lovran
- Authors:
- Vučković, Darinka (133680)
- Dadić, Elizabeta
- Abram, Maja (133610)
- Rukavina, Tomislav (163264)
- Makiš, Janko (27500)
- Dorić, Miljenko (85032)
- Editors
- Vučković, Darinka (133680)
- Žele-Starčević, Lidija
- Knežević, Predrag
Proceedings title: 3. Hrvatski kongres kliničke mikrobiologije - Knjiga sažetaka
Language: hrvatski
Place: Zagreb
Year: 1993
Pages: from 30 to 30
Meeting: 3. Hrvatski kongres kliničke mikrobiologije
Held: from 10/13/93 to 10/15/93
- Type of paper
: Summary in proceedings
Title: Numerical key for the identification of gram-negative
nonfermentative bacteria
- Authors:
- Rukavina, Tomislav (163264)
- Abram, Maja (133610)
- Vučković, Darinka (133680)
- Makiš, Janko (27500)
- Dorić, Miljenko (85032)
- Editors
- Vučković, Darinka (133680)
- Žele-Starčević, Lidija
- Knežević, Predrag
Proceedings title: 3. Hrvatski kongres kliničke mikrobiologije - Knjiga sažetaka
Language: hrvatski
Place: Zagreb
Year: 1993
Pages: from 42 to 42
Meeting: 3. Hrvatski kongres kliničke mikrobiologije
Held: from 10/13/93 to 10/15/93
- Type of paper
: Summary in proceedings
Title:
- Authors:
- Abram, Maja (133610)
- Dorić, Miljenko (85032)
Proceedings title: Abstract book
Language: engleski
Place: Prag, Češka
Year: 1994
Pages: from 165 to 165
Meeting: 7th International Congress of Bacteriology and Applied Microbiology Division
Held: from 07/03/94 to 07/08/94
Summary: In our laboratory Listeria monocytogenes infection was
studied in BALB/c and C57Bl/6 mice depleted of CD8+, CD4+ and NK cells.
Mice depleted of different T cell subpopulations remained capable of
resolving a primary infection. However, the absence of CD8+ T cells,
resulted in slower resolution of the infection. On the other hand NK cells
seem to have no influence on the resolution of this intracellular
infection.
Keywords: Listeria monocytogenes, depletion, T lymphocytes NK cells
- Type of paper
: Summary in proceedings
Title:
- Authors:
- Abram, Maja (133610)
- Dorić, Miljenko (85032)
- Rukavina, Tomislav (163264)
Proceedings title: Periodicum Biologorum
Language: engleski
Place: Zagreb
Year: 1994
ISBN/ISSN: 0031-5362
Pages: from 275 to 275
Meeting: Mechanisms in local immunity; 2nd Alps-Adria Immunology and Allergology Meeting
Held: from 09/26/94 to 09/28/94
Summary: We analyzed the primary infection with L.monocytogenes in
BALB/c, C57Bl/6 and beta2M-/- mice, depleted of different cell populations.
Mice depleted of different T cell subpopulations remained capable of
resolving a primary infection as well as was in the case of beta2M-/- mice.
In the case of pregnant mice it seems that L.monocytogenes can traverse the
placental barrier very soon after exposure. This was proved during
different periods of gastation by fetal resorption, abortion, stillbirth or
neonatal infection.
Keywords: primary listeriosis, BALB/c, C57Bl/6, beta2M-/- mice
- Type of paper
: Summary in proceedings
Title:
- Authors:
- Abram, Maja (133610)
- Dorić, Miljenko (85032)
Proceedings title: Abstract book
Language: engleski
Place: San Francisco, USA
Year: 1995
Pages: from 342 to 342
Meeting: The 9th International Congress of Immunology
Held: from 07/23/95 to 07/29/95
Summary: We analyzed the effects of in vivo depletion of NK and
different T cell populations, on clearance of L.monocytogenes in the liver
and spleen, during primary infection in BALB/c, C57Bl/6 and beta2M-/- mice.
In vivo depletion of NK cells in C57Bl/6 mice did not influence the course
of primary listeriosis. After in vivo administration of anti-CD4 mAb,
anti-CD8 mAb or a combination of both mAbs, mice remained capable of
resolving the primary L.monocytogenes infection, but the duration was
prolonged.
Keywords: in vivo depletion, BALB/c, C57Bl/6, beta2M-/-, primary listeriosis
- Type of paper
: M.A.
Title: The influence of betalactams on the mechanisms of specific
and nonspecific resistance
Faculty: Medicinski fakultet Sveučilište u Rijeci
Date of defense: 02/07/92
Language: hrvatski
Number of pages: 89
Summary: The influence of beta-lactams antibiotics on the host
defencesystem and the cellularity of the spleen by using the direct
PFCassay in an animal model on CBA mice, has been analyzed.Penicillin G,
ceftazidime and ceftriaxone modulated the immuneresponse. Ceftazidime had
the most pronounced immunostimulatingeffect.
Keywords: beta-lactam antibiotics, plaque forming cell assay (PFC), immunomodulation
- Type of paper
: M.A.
Title: Changes in phagocyte function during chemotherapy
Faculty: Medicinski fakultet Sveučilište u Rijeci
Date of defense: 07/23/92
Language: hrvatski
Number of pages: 84
Summary: Physiological differences in adherence and spreading
ofperitoneal macrophages in four strains of mice were analyzed.
Theinfluence of different antibiotics on these functions was alsoexamined.
The changes in adherence were seen in mice treated withtherapeutic doses of
penicillin G and cefotaxime. Cefotaxime,streptomycin and lincomycin in the
therapeutic dose as well asceftazidime and lincomycin in a four fold higher
dose influencedthe spreading of those cells.
Keywords: peritoneal macrophages, penicillin G, cefotaxime, ceftazidime, streptomycin, lincomycin
- Type of paper
: M.A.
Title: The influence of macrolide, aminoglycoside and beta-lactam
antibiotics on humoral immunological reactivity
Faculty: Medicinski fakultet Sveučilište u Rijeci
Date of defense: 07/24/92
Language: hrvatski
Number of pages: 98
Summary: The influence of some beta-lactam, macrolide and
aminoglycozideantibiotics on the proliferative response of B
lymphocytesinduced by pokeweed mitogen was examined. The results
werecompered with the appearance of the bacterial resistance againstthe
same antibiotics in clinical practise. The changes in theproliferation were
obtained in experiments with ceftriaxone,ceftazidime, streptomycin,
netilmicin and erythromycine.Interestingly, the observed increase of the
resistance is sloweragainst antibiotics with stimulatory effect on the
proliferationof B lymphocytes (ceftazidime and erythromycine).
Keywords: B lymphocytes, bacterial resistance, beta-lactam antibiotics, macrolides, aminoglycosides
- Type of paper
: M.A.
Title: The effect of different antibiotics on T cell functions
Faculty: Medicinski fakultet Sveučilište u Rijeci
Date of defense: 07/22/92
Language: hrvatski
Number of pages: 106
Summary: The effect of different antibiotics on the proliferation of
Tlymphocytes induced with policlonal mitogens was analyzed. Theresults
showed that beta-lactam antibiotics, aminoglycosides,tetracyclines and
lincosamides suppress the proliferativeresponse of lymphocytes in a dose
dependent manner. The mostoften used macrolide, erythromycine stimulated
the T cellpopulation while azitromycin had no immunomodulatory effect.
Keywords: T lymphocytes, immunomodulation, antibiotics
- Type of paper
: Mentorship
Title: The effect of different antibiotics on T cell functions
Faculty: Medicinski fakultet Sveučilište u Rijeci
Mentor: ADLER NEVENKA
Date of defense: 07/22/92
Number of pages: 106
Author: Tićac Mr. sc. Brigita
Degree level: M.A.
- Type of paper
: Mentorship
Title: The influence of macrolide, aminoglycoside and beta-lactam
antibiotics on humoral immunological reactivity
Faculty: Medicinski fakultet Sveučilište u Rijeci
Mentor: ADLER NEVENKA
Date of defense: 07/24/94
Number of pages: 98
Author: Rukavina Mr. sc. Tomislav
Degree level: M.A.
- Type of paper
: Mentorship
Title: The influence of betalactams on the mechanisms of specific
and nonspecific resistance
Faculty: Medicinski fakultet Sveučilište u Rijeci
Mentor: ADLER NEVENKA
Date of defense: 02/07/92
Number of pages: 89
Author: Abram Mr.sc. Maja
Degree level: M.A.
- Type of paper
: Mentorship
Title: Changes in phagocyte function during chemotherapy
Faculty: Medicinski fakultet Sveučilište u Rijeci
Mentor: ADLER NEVENKA
Date of defense: 07/23/92
Number of pages: 84
Author: Vučković Mr. sc. Darinka
Degree level: M.A.
- Type of paper
: Computer program
Title: Identification of gram-positive roundshaped bacteria
- Authors:
- Makiš, Janko (27500)
Odering party: Zavod za mikrobiologiju i parazitologiju, Medicinski fakultet
Institution depot: Zavod za mikrobiologiju i parazitologiju, Medicinski fakultet
HW platform: AT-12 MHz, RAM 1MB, IBM kompatibilno
Operating system: MS-DOS
Programming language: Quick basic 4.50
Year: 1991
Summary: The computer package consist of 5 programs (55050 B; 91842
B;65000 B; 36408 B i 45288 B). The first package enables thedifferentiation
of the genera: Micrococcus, Stomatococcus,Gemella, Leuconostoc,
Pediococcus, Staphylococcus andStreptococcus. The remaining programs enable
the identificationof the other genera (in total 68 species). The programs
include 8biochemical tests of the routine set and 38 additionalbiochemical
tests.
- Type of paper
: Computer program
Title: Identification of gram-negative nonfermentative bacteria
- Authors:
- Makiš, Janko (27500)
Odering party: Zavod za mikrobiologiju i parazitologiju, Medicinski fakultet
Institution depot: Zavod za mikrobiologiju i parazitologiju, Medicinski fakultet
HW platform: AT-12 MHz, RAM 1MB, IBM kompatibilno
Operating system: MS-DOS
Programming language: Quick basic 4.50
Year: 1991
Summary: The computer package consist of 5 programs (89098 B; 83560
B;58440 B; 58438 B and 32294 B). On the basis of 10 biochemicaltests of the
routine set and 59 additional tests, it is possibleto identify 94 species
of nonfermentative bacteria.
- Type of paper
: Computer program
Title: Identification of yeasts and yeast-like fungi
- Authors:
- Makiš, Janko (27500)
Odering party: Zavod za mikrobiologiju i parazitologiju, Medicinski fakultet
Institution depot: Zavod za mikrobiologiju i parazitologiju, Medicinski fakultet
HW platform: AT-12 MHz, RAM 1MB, IBM kompatibilno
Operating system: MS-DOS
Programming language: Quick basic 4.50
Year: 1992
Summary: The program (88952) allows the identification of 56 species
ofyeasts and yeast-like fungi from 11 genera. The biochemical testswere
choosen on the basis of the author's own method i.e.establishment of
separative values, using all the disposablebiochemical tests.
- Type of paper
: Other
Title:
- Authors:
- Abram, Maja (133610)
- Dorić, Miljenko (85032)
Type of work: poster u John-Humphrey-Course on "Modulation of the Immune Response"
Language: engleski
Summary: Protection against intracellular pathogens often requires
the induction of a pathogen-specific T-cell-mediated immune response. To
investigate the role of T cell subsets in resistance to primary infection
with L.monocytogenes, we depleted different strains of mice (BALB/c,
C57Bl/6, beta2M-/-) of CD4+ and/or CD8+ T cells, in vivo, by administration
of specific mAbs. We found that all mice, even beta2 microglobulin
deficient mice, which lack CD8+ lymphocytes, remained capable to eliminate
the primary L.monocytogenes infection, indicating the involvement of other
defence mechanisms.
Keywords: primary listeriosis, in vivo depletion, T cell subpopulations
- Type of paper
: Other
Title:
- Authors:
- Abram, Maja (133610)
Type of work: poster u 2nd Alpe-Adria Clinical Microbiology Summer School
Language: engleski
- Type of paper
: Other
Title:
- Authors:
- Vučković, Darinka (133680)
Type of work: poster u 2nd Alpe-Adria Clinical Microbiology Summer School
Language: engleski
- Type of paper
: Other
Title:
- Authors:
- Rukavina, Tomislav (163264)
- Tićac, Brigita (163253)
Type of work: poster u 2nd Alpe-Adria Clinical Microbiology Summer School
Language: engleski
