SVIBOR - Papers quoted in CC - project code: 3-01-172

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SVIBOR - Collecting Data on Projects in Croatia

Papers quoted in Current Contents on project 3-01-172

Quoted papers: 6
Other papers: 51
Total: 57

Title:

Authors:: Petković, Iskra (36570); Ligutić, Ivo; Dominis, Mara; Loffler-Badžak, Dagmar; Ćepulić, Mladen (110195); Nakić, Melita (74392)

Journal: Cancer Genetics Cytogenetics
ISSN: 0165-4608
Volume: 60
Year: 1992
Pages: from 158 to 163
Number of references: 24
Summary: We presented the results of cytogenetic analysis in a brother andsister with ataxia telangiectasia (AT), one of whom had malignantT-cell lymphoma. In both children, cytogenetic analysis ofphytohemagglutinin (PHA)-stimulated lymphocytes showedchromosomal instability and inv(7) in 10% of the cells examined.The malignant lymphoma was analyzed cytogenetically on slidesobtained from short-term culture of the lymph node cells; 64cells were analized. A heterogeneous cel population was noted.Fourteen cells (21.9%) had a normal male karyotype;t(7;14)(p14;q12) and inv(7)(p14q35) were observed in 6.3% and3.1% of metaphases. Owing to low frequency, these cells areprobably a characteristic of the basic disease and have nofeatures of malignant cells. Forty cells (62.5%) had apseudodiploid karyotype 46,XY,del(1)(p22p36), del(5)(q33),del(12)(p11), without cytogenetically evident aberrations ofchromosomes 7 and 14. The results of these investigations suggestthat the cells with rearrangements of chromosomes 1, 5 and 12 aremalignant cells and did not originate by transformation of cellswith inv(7) and t(7;14).

Title:

Authors:: Petković, Iskra (36570); Konja, Josip (76313); Nakić, Melita (74392)

Journal: Cancer Genetics Cytogenetics
ISSN: 0165-4608
Volume: 58
Year: 1992
Pages: from 155 to 159
Number of references: 25
Language: engleski
Summary: In this work we present the results of cytogenetic analysis ofthe malignant cells in 27 children with acute nonlymphocyticleukemia (ANLL). The aim of our investigations was to determinethe frequency and types of chromosome aberrations in ourpopulation of children with ANLL. Successful cytogeneticanalysis was carried out in 24 (89%) patients. Aberrantkaryotype of malignant cells were estabished in 58% of the cases.The most frequent chromosomal abnormality was t(8;21), identifiedin 5 (20.8%) patients i.e., 4 of 10 M2-ANLL. Aberration frequencyof chromosome 11 was 16.6% and was identified in 3 of 8 M5-ANLL.Trisomy 8 and monosomy 7 were identified in one patient each with M3 and M2-ANLL, respectively. del(13), a rare chromosomeaberration in hemoblastoses , was found in a child with M1,t(8;21) and the loss of chromosome y. Translocation t(1;11;21)with a break in region 1p23, 11q23 and 21q22, is unusual and wasidentified in a boy with M2-ANLL; it can be considered as avariant form of the t(8;21).

Title:

Authors:: Petković, Iskra (36570); Nakić, Melita (74392); Konja, Josip (76313)

Journal: Cancer Genetics Cytogenetics
ISSN: 0165-4608
Volume: 54
Year: 1991
Pages: from 67 to 69
Number of references: 13
Language: engleski
Summary: An analysis of the C-segment variability of chromosomes 1, 9 and16 was carried out in 38 children with ALL, and 90 controlsubjects. When studying location variants, no differences werefound between group of patients and the normal controls. A largerquantity of structural heterochromatin was , however, observed onchromosomes 1, 9 and 16, and a higher frequency of homologouschromosomes heteromorphism in children with ALL when comparedwith the control group.

Title:

Authors:: Petković, Iskra (36570); Ćepulić, Mladen (110195)

Journal: Cancer Genetics Cytogenetics
ISSN: 0165-4608
Volume: 55
Year: 1991
Pages: from 231 to 234
Number of references: 11
Language: engleski
Summary: The results of a direct cytogenetic tumor analysis in a 21/2-year- old girl with metastatic neuroblastoma are presented inthis paper. Investigations established a modal karyotype of 46chromosomes with several marker chromosomes. Beside del(1)(p31),hsr, and dmin chromosomes in all the cells analyzed, terminaldeletion of the long arm of chromosome 14 was also identified.Malignant cells were thus monosomic for segment 14q24->qter.

Title:

Authors:: Petković, Iskra (36570); Nakić, Melita (74392); Ćepulić, Mladen (110195); Konja, Josip (76313)

Journal: Cancer Genetics Cytogenetics
ISSN: 0165-4608
Volume: 65
Year: 1993
Pages: from 167 to 169
Number of references: 9
Language: engleski
Summary: We report the results of cytogenetic analysis in two childrenwith neuroblastoma. The analysis was performed on slides obtainedfrom 24-hour bone marrow (BM) culture or by a direct method ofthe primary tumor tissue. The structural and numericalaberrations were established, including structural aberrations ofchromosome 1. The finding of i(1q) and t(1;5)(p22;q13) is ofinterest because these chromosome aberrations are rare in thistype of disease.

Title:

Authors:: Petković, Iskra (36570)

Journal: Cancer Genetics Cytogenetics
ISSN: 0165-4608
Volume: 76
Year: 1994
Pages: from 125 to 128
Number of references: 25
Language: engleski
Summary: The results of a cytogenetic analysis in an embryonal rhabdomyosarcoma are presented. A tetraploid karyotype with double minutes chromosomes (dmin) was identified using a direct method of tumor tissue treatment. In 5% of the examined cells, evidence of spontaneous cell fusion was observed.


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