SVIBOR - Project code: 3-01-201


Strossmayerov trg 4, HR - 10000 ZAGREB
tel.: +385 1 459 44 44, fax: +385 1 459 44 69


SVIBOR - Collecting Data on Projects in Croatia

Project code: 3-01-201

Early detection of ovarian cancer by transvaginal color Doppler

Main researcher: KURJAK, ASIM (24866)

Type of research: developmental
Duration from: 01/01/89. to 12/31/95.

Papers on project (total): 158
Papers on project quoted in Current Contents: 18
Institution name: Bolnica "Sveti duh", Zagreb (129)
Department/Institute: Department of obstetrics and gynecology
Address: Sveti Duh 64
City: 10000 - Zagreb, Croatia
Phone: 385 (0) 41 57 92 51
Fax: 385 (0) 41 57 92 48

Summary: The objective of the study is assessment of the adnexal tumor vascularization with transvaginal color and pulsed Doppler sonography. Vessel location, its arrangement and pulsed Doppler waveform characteristics will be used to distinguish benign from malignant vascularity. Study is designed as prospective one in which sonographic and personal records of all women in this period will be investigated.

Keywords: Transvaginal color and pulsed Doppler, ovarian tumors, neovascularization

Research goals: Although there has been significant progress in the surgery, radiotherapy and chemotherapy of ovarian carcinoma the mortality rate has not decreased appreciable in the past 20 years. Indeed, more fundamental and logical step is the early detection of cancer in asymptomatic women by screening. As there is no known precursor, any screening test will have to be sensitive for early cancer, as well as being highly specific. Such a test must be evaluated for validity and acceptability and would than have to be incorporated in a trial of screening efficacy, with mortality from the disease as the end-point. A number of different screening methods have been applied in an international trials during the last five years. Among thousands of women screened and many operated on, only a few had cancers that were detected. Most of detected tumors were already advanced, had border-line pathologic features suggesting indolent biologic behavior, or were already associated with a clinically identifiable pelvic mass. Obviously, efforts are continuing and its seems that some improvement can be expected using transvaginal color and pulsed Doppler.


  1. Name of institution: Wintroph University
    Type of institution: Economical/Production
    City: New York, USA

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Last update: 04/20/95