- Type of paper
: Book
Title: Handbook of war medicine for general practitioners
- Authors:
- Baklaić, Ž.
- Geber, J.
- Granić, m.
- Hančević, J.
- Hebrang, A.
- Hranilović, B.
- Husar, J
- Janjić, I.
- Kostović, I.
- Ljubičić, M.
- Mihatov, Šime (97500)
- Muačević, V.
- Nanković, V.
- Prodan, I.
- Vodopija, I.
- Vuinac, T.
Publisher: Štab saniteta Republike Hrvatske
Year: 1991
Number of pages: 79
Language: hrvatski
- Type of paper
: Book
Title:
- Editors
- Radić, Berislav (39626)
- Mihatov, Šime (97500)
Publisher: Naprijed
- Type of paper
: Paper in book
Title: Balloon-tipped flow directed catheterization
- Authors:
- Mihatov, Šime (97500)
- Editors
- Vrhovac, B.
- Bakran, I.
- Granić, m.
- Jakšić, B.
- Labar, B.
- Vucelić, B.
Publisher: Naprijed
Year: 1991
Pages: from 582 to 584
Language: hrvatski
- Type of paper
: Paper in book
Title: Myocardial infarction
- Authors:
- Mihatov, Šime (97500)
- Batinić, Z.
- Editors
- Vrhovac, B.
- Bakran, I.
- Granić, m.
- Jakšić, B.
- Labar, B.
- Vucelić, B.
Publisher: Naprijed
Year: 1991
Pages: from 723 to 737
Number of references: 26
Language: hrvatski
- Type of paper
: Paper in book
Title: Traumatic cardiac injury
- Authors:
- Mihatov, Šime (97500)
- Editors
- Vrhovac, B.
- Bakran, I.
- Granić, m.
- Jakšić, B.
- Labar, B.
- Vucelić, B.
Publisher: Naprijed
Year: 1991
Pages: from 769 to 770
Number of references: 4
Language: hrvatski
- Type of paper
: Paper in book
Title: Cardiomyopathy
- Authors:
- Planinc, Danijel (153316)
- Editors
- Vrhovac, B.
- Bakran, I.
- Granić, m.
- Jakšić, B.
- Labar, B.
- Vucelić, B.
Publisher: Naprijed
Year: 1991
Pages: from 674 to 686
Number of references: 14
Language: hrvatski
- Type of paper
: Paper in book
Title: Valvular heart disease
- Authors:
- Rudar, M
- Planinc, Danijel (153316)
- Editors
- Vrhovac, B.
- Bakran, I.
- Granić, m.
- Jakšić, B.
- Labar, B.
- Vucelić, B.
Publisher: Naprijed
Year: 1991
Pages: from 649 to 664
Number of references: 8
- Type of paper
: Paper in book
Title: Rheumatic fever
- Authors:
- Radić, Berislav (39626)
- Editors
- Vrhovac, B.
- Bakran, I.
- Granić, m.
- Jakšić, B.
- Labar, B.
- Vucelić, B.
Publisher: Naprijed
Year: 1991
Pages: from 646 to 649
Number of references: 6
Language: hrvatski
- Type of paper
: Paper in book
Title: Neurocirculatory asthenia
- Authors:
- Radić, Berislav (39626)
- Editors
- Vrhovac, B.
- Bakran, I.
- Granić, m.
- Jakšić, B.
- Labar, B.
- Vucelić, B.
Publisher: Naprijed
Year: 1991
Pages: from 759 to 759
Number of references: 3
Language: hrvatski
- Type of paper
: Paper in book
Title: Cardiac transplantation
- Authors:
- Planinc, Danijel (153316)
- Editors
- Vrhovac, B.
- Bakran, I.
- Granić, m.
- Jakšić, B.
- Labar, B.
- Vucelić, B.
Publisher: Naprijed
Year: 1991
Pages: from 766 to 768
Number of references: 6
Language: hrvatski
- Type of paper
: Paper in book
Title: Value of Holter monitoring in the treatment of ventricular
tachycardia
- Authors:
- Radić, Berislav (39626)
- Editors
- Petrač, D.
Publisher: Naprijed
Year: 1992
Pages: from 53 to 58
Number of references: 23
- Type of paper
: Paper in book
Title: The electric stimulation of the heart
- Authors:
- Radić, Berislav (39626)
- Mihatov, Šime (97500)
- Editors
- Duraković, Z.
Publisher: Naprijed
Year: 1993
Pages: from 151 to 161
Number of references: 8
Language: hrvatski
- Type of paper
: Paper in book
Title: Quantification in electrocardiography
- Authors:
- Bergovec, Mijo (138132)
- Mihatov, Šime (97500)
- Editors
- Duraković, Z.
Publisher: Naprijed
Year: 1993
Pages: from 198 to 206
Number of references: 13
Language: hrvatski
- Type of paper
: Paper in book
Title: Exercise electrocardiography
- Authors:
- Mihatov, Šime (97500)
- Editors
- Duraković, Z.
Publisher: Naprijed
Year: 1993
Pages: from 206 to 229
Number of references: 17
Language: hrvatski
- Type of paper
: Paper in book
Title: Dynamic electrocardiography
- Authors:
- Radić, Berislav (39626)
- Mihatov, Šime (97500)
- Editors
- Duraković, Z.
Publisher: Naprijed
Year: 1993
Pages: from 229 to 238
Number of references: 13
Language: hrvatski
- Type of paper
: Paper in book
Title: Electrocardiogram in heart muscle diseases
- Authors:
- Planinc, Danijel (153316)
- Mihatov, Šime (97500)
- Editors
- Duraković, Z.
Publisher: Naprijed
Year: 1993
Pages: from 239 to 253
Number of references: 11
Language: hrvatski
- Type of paper
: Paper in book
Title:
- Editors
- Mihatov, Šime (97500)
- Type of paper
: Paper in journal
Title:
- Authors:
- Planinc, Danijel (153316)
- Jerić, Marijan (114021)
- Mihatov, Šime (97500)
- Omčikus-Pevalek, Mirjana (97592)
- Pagon, Lj.
- Rudar, M
Journal: Acta cardiologica
Number: 1
Volume: 46
Year: 1991
Pages: from 79 to 83
Number of references: 9
Language: engleski
Summary: For the evaluation of patients wits prosthetic heart
valvesDoppler echocardiography is superior over other noninvasivetechniques
because it allows quantitative assessment of valvefunction.As a noninvasive
method Doppler is safe,easilyrepeatable and provides haemodynamic data that
closely correlatewith parameters obtained by invasive procedures.
The purpose of our study was to evaluate Dopplercharacteristics of
mechanical and tissue
mitralprosthesis:Star-Edwards,Bjork-Shiley,Hall-Medtronic and Hancockin
patients with clinically normal valve function.
Keywords: Doppler echocardiography,prosthetic heart valve,noninvasive technique,heart valves function
- Type of paper
: Paper in journal
Title: The value of ECG and enzyme determination in the
assessment of myocardial infarction size:correlation with ejection fraction
during subacute and chronic phase
- Authors:
- Bergovec, Mijo (138132)
- Vukosavić, Đuro (96240)
- Mihatov, Šime (97500)
- Žigman, Miroslav (141166)
- Prpić, Hrvoje (145593)
- Birtić, Krešimir (3784)
- Nikolić-Heitzler, Vjeran (101623)
- Sjerobabski, V.
- Franceschi, Dinko (81241)
Journal: Acta Clinica Croatica
Number: 3
Volume: 30
Year: 1991
Pages: from 165 to 176
Number of references: 40
Language: hrvatski
Summary: The size of myocardial infarction (MI) was determineted
bygramequivalent(gEq) isoenzyme MB creatine kinase(MB-CK) and byECG using
Selvester's QRS scoring system in 71 patients with thefirst acute MI(45
patients with anterior and 26 patients withinferior MI).The global left
ventricular ejection fraction(GEF)estimated by radionuclide
ventriculography was determinated inthe same group of patients in the
subacute and chronic phasesafter suffering MI.The relationship between the
size of the no statistically significant difference between the size
ofanterior and inferior infarction determinedenzymatically(22,54+-13,78 vrs
20,90+-13,76;p=0,59 NS)The size ofMI determined by ECG was significantly
larger in the group ofpatients with anterior MI(9,57+-3,36 vrs
4,47+-2,63;p=0,001).Insubacute and chronic phases GEF values were
significantly lowerin anterior than in inferior MI.A good negative
correlationbetween the size of MI determined by ECG and GEF was found
insubacute and chronic phases in anterior and infeior MI.Thecorrelation
between the size of MI determined by gEq and GEF wasweaker in anterior MI
and poor in inferior MI in bothpostinfarction phases.We concluded that the
QRS scoring system isa noninvasive and simple method of determining the
size ofMI,especially in inferior infarcts,where enzymatic determinationsare
insufficient.
Keywords: infarct size,gramequivalent,QRS scoring system,global ejection fraction,radionuclide ventriculography
- Type of paper
: Paper in journal
Title: Clinical significance of QRS complex for estimating
myocardial infarction size
- Authors:
- Bergovec, Mijo (138132)
- Vukosavić, Đuro (96240)
- Mihatov, Šime (97500)
- Birtić, Krešimir (3784)
- Nikolić-Heitzler, Vjeran (101623)
- Sjerobabski, V.
- Barić, Lj.
Journal: Liječnički vjesnik
Number: 9
ISSN: 0024-3477
Volume: 113
Year: 1991
Pages: from 309 to 313
Number of references: 43
Language: hrvatski
Summary: In 60 patients myocardial infarction size was determined
byelectrocardiogram(ECG) using Selvester's QRS scoring system.Thesevalues
were compared with the size of infarction as determinedenzymatically using
gramequivalent isoenzyme MB creatinekinase(gEq)and using maximum values of
isoenzyme MB-CK.Theresults showed no statistically significant difference
betweenthe size of anterior and inferior infarction determined
bygEq(25,19+-13,59 vrs 22,48+-14,04;p=0,12 NS) and by maximum
MB-CK(125,5+-76,0 vrs 98,4+-60,7;p=0,12 NS).The size of
myocardialinfarctions determined by ECG was significantly larger
anteriorlycompared with the inferior infarcts(9,6+-2,9
vrs4,5+-2,6;p=0,001).In patients with anterior infarcts goodcorrelations
between the sizeof infarction determined by QRSscoring system and by gEq or
maximum MB-CK were found(r=0,69;p=0,004 and r=0,72;p=0,001).In patients
with inferiorinfarcts the correlations between QRS score and gEq or
maximumMB-CK were poor (r=0,37;p=0,02 and r=0,45;p=o,15).The causes ofweak
correlations in the results of described methods in inferiorinfarcts are
discussed.Thus QRS scoring system provides newnoninvasive and simple
possibilities in determing the size ofanterior and in inferior infarctions
of the left ventricle.
Keywords: myocardial infarction,electrocardiography
- Type of paper
: Paper in journal
Title:
- Authors:
- Bergovec, Mijo (138132)
- Mihatov, Šime (97500)
- Prpić, Hrvoje (145593)
- Rogan, S.
- Batarelo, V
- Sjerobabski, V.
Journal: The Lancet
Volume: 339
Year: 1992
Pages: from 303 to 0
Language: engleski
Summary: We have investigated the effect of additional stress,caused
bybombardments and war operations every day,on the frequency ofacute
coronary events among civilians in Croatia.
Our investigation was done in part of the Zagreb area,the capitalof
Croatia,ans its surroundings in Sepetember,1991,with specialattention
focused on the second half of the mont,when the firstair raid sirens were
sounded.Our hospital is a tertiary carecentre with 1200 beds (240 beds in
the department of intenalmedicine) with a catchment of about 300.000
inhabitants.
As Meisel at al. showed,we found a higher frequency of MI duringthe study
period than in the previous year(table).Deaths due toMI in patients with or
without q-wave also increased,by contrastwith Meisel and colleagues'
findings,no rise in deaths fromanterior MI was noted.
The increased hospital mortality among patients with acute MIduring
September,1991,could been due to the frequent air raidalarms.An additional
stress was that lifts could not be used fortransporting patients to the
shelters.These factors increased theexisting mental stress,possibly causing
regfactory malignantarrhythmia or heart failure.
The war in Croatia,ai addition to known casualties,also has itsvictims
among patients with coronary artery disease.
- Type of paper
: Paper in journal
Title:
- Authors:
- Planinc, Danijel (153316)
- Franceschi, Dinko (81241)
- Žigman, Miroslav (141166)
- Jerić, Marijan (114021)
- Pagon, Lj.
- Mihatov, Šime (97500)
- Rudar, M
Journal: Acta cardiologica
Number: 4
Volume: 47
Year: 1992
Pages: from 391 to 401
Number of references: 14
Language: engleski
Summary: The intensive use of echocardiography increases the
probabilityof correct diagnosis of amyloid cardiomyopathy,but on the
otherhand increasesd the risk of erroneously diagnosing cardiacamyloidosis
as hypertrophic cardiomyopathy which was the case inthree out of five our
patients.
In combination with EKG finding of low voltage and positive
99mTcpyrophosphate myocardial uptake,echocardiography is
veryuseful,specific and sensitive method in differential diagnosis
ofinfiltrative cardiomyopathy,and it is a method of choice in
earlydiagnosis of cardiac amyloidosis.
Echocardiography is easy to perform and it can be used forlongitudinal
folow-up of patients to demonstrate the evolution ofcardiac amyloidosis
which is of great importance in makingtherapeutic decisions.
Keywords: amyloid cardiomyopathy,Tc-99m-PYP
- Type of paper
: Paper in journal
Title: Influence of the war induced stress in Croatia on the
incidence and mortality of acute ischemic disease
- Authors:
- Bergovec, Mijo (138132)
- Mihatov, Šime (97500)
- Prpić, Hrvoje (145593)
- Nikolić-Heitzler, Vjeran (101623)
- Rogan, S.
- Batarelo, V
- Sjerobabski, V.
Journal: Wiener Medizinische Wochenschrift
Volume: 19
Year: 1992
Pages: from 430 to 433
Number of references: 12
Language: njemački
- Type of paper
: Paper in journal
Title:
- Authors:
- Nikolić-Heitzler, Vjeran (101623)
- Mihatov, Šime (97500)
- Omčikus-Pevalek, Mirjana (97592)
- Rudar, M
- Vukosavić, Đuro (96240)
- Birtić, Krešimir (3784)
Journal: Zdravniški vestnik
Number: 1
Volume: 62
Year: 1993
Pages: from 3 to 9
Number of references: 35
Language: slovenski
- Type of paper
: Paper in journal
Title: Regression of ECG signs of myocardial infarction related
to infarct size and left ventricular function
- Authors:
- Bergovec, Mijo (138132)
- Prpić, Hrvoje (145593)
- Žigman, Miroslav (141166)
- Vukosavić, Đuro (96240)
- Birtić, Krešimir (3784)
- Mihatov, Šime (97500)
- Franceschi, Dinko (81241)
- Barić, Lj.
Journal: Journal of Electrocardiography
Number: 1
Volume: 26
Year: 1993
Pages: from 1 to 8
Number of references: 41
Language: engleski
Summary: Quantitative and qualitative analysis of Q waves and QRS
scoreswas performed on 69 patients during the early phase of
firstmyocardial infarction (MI) and 6 months subsequently.Theregression of
ECG signs of MI were compared with theenzymatically estimated size of
MI,the location of MI,and withthe changes of global ejection fraction (GEF)
assessed byradionuclide ventriculography.Among 57 patients with Q wave MI
acomplete disappearance of ECG signs was found in 9(15.7%)Patients with MI
of inferior location showed asignificantly higher reduction of Q waves
(p<0.001) and QRSscores (P<0.001) than the anterior MI group.In the group
of 12patients with the Q wavw MI,11 demonstrated complete regressionof MI
signs.Among all Q wave and non Q wave MIs,the authors foundno significant
difference in the size of MI.The median of thepercent of change of the QRS
score was significantly higher(p=0.04) in the group of patients with
improved GEFs than in thergroup of patients withdecreased or unchanged GEfs
6 monthsfollowing acute MI.The sensitivity,specificity,and predictivevalues
for improved left ventricular function according to thechange of Q waves
and ECG scores were 91%,32% and 62%;forchangesof Q waves 81%,40%,and 63%
for changes of ECG scores91%,36% and 64%,respectively.In the group of
patients with non Qwave MI these values were 100%,50% and,91% as a result
of St-Tdisappearance.
Keywords: Q wave regression,QRS scoring system,infarct size,global ejection fraction
- Type of paper
: Paper in journal
Title:
- Authors:
- Bergovec, Mijo (138132)
- Žigman, Miroslav (141166)
- Radić, Berislav (39626)
- Mihatov, Šime (97500)
- Vukosavić, Đuro (96240)
Journal: The International Journal of Cardiac Imaging
Volume: 9
Year: 1993
Pages: from 39 to 48
Number of references: 57
Language: engleski
- Type of paper
: Paper in journal
Title: The value of exercise testing in diagnosis of ischemic
heart disease
- Authors:
- Mihatov, Šime (97500)
Journal: Liječnički vjesnik
Number: 3
ISSN: 0024-3477
Volume: 115
Year: 1993
Pages: from 108 to 114
Number of references: 39
Language: hrvatski
Summary: New knoledges of contemporary cardiology have
createdpossibilities for critical reevaluation of current criteria
inexercise testing and have shown its new diagnostic and prognosticvalue.A
multifactorial approach to exercise testing includes ananalysis of ECG
criteria and hemodynamic parameters obtainedduring exercise testing.This
approach increases the value ofstress testing in diagnosis,assessment of
the severity andprognosis of coronary artery disease.The inclination
towardarrhythmias,detection of asymptomatic ischemia and earlydetection of
a dysfunction of the left ventricle have beenemphasized.The indications for
use and termination of exercisetesting absolute and relative
contraindications for exercisetesting are critically disdussed.The
sensitivity of exercisetesting is 60 to 80 percent and specificity level
ranges between85 to 90 percent.The incidence of serious complications
isdecreased about 50 percent by a careful screening of patients
andappropriate safety level.
Keywords: coronary disease,diagnosis,exercise test
- Type of paper
: Paper in journal
Title:
- Authors:
- Bergovec, Mijo (138132)
- Prpić, Hrvoje (145593)
- Mihatov, Šime (97500)
- Žigman, Miroslav (141166)
- Vukosavić, Đuro (96240)
- Birtić, Krešimir (3784)
- Franceschi, Dinko (81241)
- Barić, Lj.
Journal: European Heart Journal
Volume: 14
Year: 1993
Pages: from 1102 to 1109
Number of references: 59
Language: engleski
- Type of paper
: Paper in journal
Title:
- Authors:
- Nikolić-Heitzler, Vjeran (101623)
- Bergovec, Mijo (138132)
- Prpić, Hrvoje (145593)
- Tomljanović, V
- Stančić, V
- Gopčević, A
- Mihatov, Šime (97500)
Journal: Wiener Medizinische Wochenschrift
Number: 143
ISSN: 0043-534
Volume: 18
Year: 1993
Pages: from 479 to 481
Number of references: 25
Language: engleski
- Type of paper
: Paper in journal
Title: The significance of infrahisal atrioventricular block of
second degree induced by atrial pacing in patients with syncope and bundle
branch block
- Authors:
- Petrač, D.
- Vukosavić, Đuro (96240)
- Birtić, Krešimir (3784)
Journal: Acta Clinica Croatica
Number: 1
ISSN: 0353-9466
Volume: 32
Year: 1993
Pages: from 3 to 23
Number of references: 20
- Type of paper
: Paper in journal
Title: Long-term results of catheter fulguration of ventricular
tachycardia
- Authors:
- Petrač, D.
- Vukosavić, Đuro (96240)
- Radić, Berislav (39626)
- Barić, Lj.
Journal: Acta Clinica Croatica
Number: 3
ISSN: 0353-9466
Volume: 32
Year: 1993
Pages: from 107 to 121
Number of references: 21
Keywords: ventricular tachycardia,catheter fulguration
- Type of paper
: Paper in journal
Title: Current status of thrombolytic therapy in acute myocardial
infarction-1992.
- Authors:
- Bergovec, Mijo (138132)
Journal: Liječnički vjesnik
Number: 5
ISSN: 0024-3477
Volume: 115
Year: 1993
Pages: from 170 to 179
Number of references: 60
Language: hrvatski
Summary: Tha management of acute myocardial infarction has
dramaticallychanged in the last decade.The conservative approuach with
bedrest,oxigen therapy,pain relief and prevention ofcomplications-the
former cornerstones of the treatment of acutemyocardial infarction-are now
being replaced with new,moreaggresive forms of therapy,including early
administration ofthrombolytic agents.With the more than 100.000 patients
studiedin various clinical trials in the different parts of theworld,the
use of thrombolytic therapy is probably the mostthoroughly studied medical
intervention in human medicalhistory.The results of these trials undoubtly
showed thatthrombolytic therapy had a major impact on reducing mortality
andpreserving left ventricular function in patients with acutemyocardial
infarction.The purpose of this article is to reviewcurrent new information
on thrombogenesis and thrombolysis,theindications and contraindications of
thrombolytictherapy,comparison between different thrombolytic agents and
therole of adjuvant antithrombolitic therapy.
Keywords: myocardial infarction,thrombolytic therapy
- Type of paper
: Paper in journal
Title: Acute renal failure in heart transplant recipients
- Authors:
- Gašparović, V-
- Planinc, Danijel (153316)
- Sutlić, Ž.
- Biočina, B.
- Sokolić, J.
- Gjurašin, M.
Journal: Liječnički vjesnik
Number: 5
ISSN: 0024-3477
Volume: 115
Year: 1993
Pages: from 152 to 156
Number of references: 19
Language: hrvatski
Summary: In this study the incidence and the development of acute
renalfailure(ARF) in heart transplant recipients is presented.Amongthe
thirteen heart transplant recipients eight of them developedoliguric or
nonoliguric ARF.Besides the known factors such asactual conditionn ot the
patient,kidney function,peri andpostoperative compromised circulation,our
results demonstrate thesignificance of postoperative cyclosporin
concentration incombination with the use of other drugs.The results also
show theimportance ot the way cyclosporin has been
administered.theparenteral route of appliance is connected with the greater
riskof higher drug concentration in the plasma than the peroralone.In
connection with this is the higher incidence od adversereactions to
cyclosporin given parenterally.In addition toranitidine and captopril
,which have been mentioned earlier,thefindings of our study indicate that
greater attention has to bepaid to the treatment with ketokonazol given in
combination withcyclosporin,since it results in decreaseed
cyclosporinclearance.Other nephotoxic drugs like amphotericin also
increasethe possibility of renal lesions.The incidence of acute
renalfailure in this group of patients is high.Our data suggest thatthe
reason for the development of ARF are multifactorial.Thesedata further
suggest that a reasonable way to sove nonoliguricform of acute renal
failure is to maintain the "internal balance"and that it is not neccessary
to perform extracorporalčelimination of nitrogen substances,if there are no
additionalcomplications(i.e.gastrointestinal bleeding).An early
applicationof hemodyalisis in the oliguric form of acute renal
failureenables survival in the phase,first of all,by the influence
onhyperkalemia and fluid overload.
Keywords: kidney failure,acute;heartz transplantation
- Type of paper
: Paper in journal
Title: Lipid metabolic disorders and kidney diseases
- Authors:
- Mihatov, Šime (97500)
- Kes, Petar
Journal: Lipidi
Number: 2
Year: 1993
Pages: from 10 to 13
Number of references: 8
Language: hrvatski
- Type of paper
: Paper in journal
Title: Patophysiologic mechanisms of heart failure
- Authors:
- Mihatov, Šime (97500)
- Nikolić-Heitzler, Vjeran (101623)
- Koščak, Krunoslav
Journal: Liječnički vjesnik
ISSN: 1330-4917
Volume: 115
Year: 1993
Pages: from 360 to 365
Number of references: 72
Language: hrvatski
Summary: Heart failure is a complex clinical syndrome in whose
manifestation and prognosis compensatory mechanisms have a prominent role
as a response of the organism to an elementary disturbance.There are five
basic compensatory mechanisms:Frank_Starling mechanism,structural changes
of the heart,activation of neuroendocrine mechanism,adaptation to
hypoxiaand anaerobic metabolism.The interaction between the two main
neurohumoral mechanisms,namely vasodilatatuion and vasoconstriction,has
been drawing much of the attention recently.Vasoconstriction which evolved
into maintaining cardiac output in hypovolemic state,leads to a number of
deleterious hemodynam,ic and metabolic disturbancec in the heart
failure.The organism tends to diminish this negative effects by changing
beta adrenergic pathway and by activating vasodilatative mechanisms.Once
heart failure becomes severe,vasoconstriction predominates due to a loss of
normal baroreceptor activity.It is considered that too marked activity of
neurohumoral mechanisms is a significant cause of disease progression.By
use of contemporary drugs(ACE inhibitors,bet blockers,digitalis) excesivve
vasoconstrictive mechanisms are tried to be diminished and prognosis of the
disease improved.
Keywords: heart failure,physiopathology
- Type of paper
: Paper in journal
Title: Treatment of refractory heart failure using repeated
invasive hemodynamic diagnostics
- Authors:
- Nikolić-Heitzler, Vjeran (101623)
- Mihatov, Šime (97500)
- Bergovec, Mijo (138132)
- Prpić, Hrvoje (145593)
- Radić, Berislav (39626)
Journal: Liječnički vjesnik
ISSN: 1330-4917
Volume: 116
Year: 1994
Pages: from 83 to 85
Number of references: 15
Language: hrvatski
Summary: Our study covered five patients,three men and two
women,aged 53+-13,suffering from therapeutic refractory heart
failkure.Following a comprehensive cardiological diagnostic procedure
ishemic dilated cardiomyopathy was diagnosed in four of them,while one of
the female patients was found reccurent pulmonary embolisms.All patients
underwent right herart catheterization,and on the basis of the obtained
hemodynamic parameters,the peroral treatment was either adapted od
modifed(digitalis,diuretic,ACE inhibitor).A cardio-selective beta-blocker
was introduced in two patients,while in one of tje patients ventriculart
electrostimulation was applied to accelerate the heart rate.Đright heart
catheterizatin wasrepeated after seven days when the foolowing changes were
observed;an increase in cardiac output(38%) and cardiac
index(42%),pulmonary capillary pressure(25%) ans systemic vascular
resistance(30%).Foolowing the introduction of a "new" therapy,of five
patients with NYHA IV stage,three passed to NYHA II,and two to NYHA
III.Owing to the progression of the disease,one of the female patients with
NYHA II group,undervent heart surgery,with a good result.In conclusion by
applying repeated invasive hemodynamic diagnostic procedures it is possoble
to treat effectively refractory heart failure by simple oral drug
administration.
- Type of paper
: Paper in journal
Title: Multiple organ dysfunction syndrome,Multiple organ failure
- Authors:
- Mihatov, Šime (97500)
- Mihatov, Šime (97500)
- Batarelo, V
- Vučičević, Željko
Journal: Klinička medicina
Number: 1
ISSN: 1330-058X
Volume: 2
Year: 1994
Pages: from 33 to 39
Number of references: 101
Language: hrvatski
Summary:
Multiple organ dysfunction syndrome(MODS)(multiple organ failure-MOF) is a
new term(definition from ACCS/SCCM Consensus Conference published in
Critical Care Medicine 1992.
MODS is a frequent complication of systemic inflamatory response
syndrome(SIRS),or sepsis-when infection is documented.It is also
orecipitated by such events as trauma,haemorrhagic shock,necrotic
pancreatitisd and other critical condicions.Etipathogenesis is still
obscure,Multiple organ dysfunction syndrome is clinical end stage of
systemic hypermetabolicresponse to injury.It represents the leading cause
of death in critically ill.These patients spend more days in ICU with
higher cost.The hallmark is profound is profound autocatabolism(protein
stores) and high energy expenditure.There is global microcirculatory injury
with the lungs as the primary target organ,but also with peripheral
vascular paralyĐsis,myocardial depression,disruption of protective-gut
barrier,and terminally,liver and renal failure.Source control,restoration
and maintenance of microcirculation,and metabolic(nutritional) support are
the basic principles in therapy of this syndrome.New therapies are exciting
but there is still no concensus about benefit and improvement in
mortality(antibodies against endotoxin,mediator's
antagonists,antiinflamatory agents,selective digestive decontamination and
many others.)
Keywords: multiple organ failure,shock
- Type of paper
: Paper in journal
Title: Lipoprotein (a) and coronary artery disease
- Authors:
- Mihatov, Šime (97500)
Journal: Lipidi
Number: 4
Year: 1994
Pages: from 25 to 28
Number of references: 17
Language: hrvatski
- Type of paper
: Paper in journal
Title: Incidence and hospital mortality of acute coronary disease
among civilians in Zagreb during air-raid alarms
- Authors:
- Mihatov, Šime (97500)
- Bergovec, Mijo (138132)
- Prpić, Hrvoje (145593)
- Nikolić-Heitzler, Vjeran (101623)
- Batarelo, V
- Rogan, S.
- Sjerobabski, V.
- Mirat, Jure
Journal: Acta Medica Croatica
Number: 2
ISSN: 1330-0164
Volume: 49
Year: 1995
Pages: from 49 to 52
Number of references: 16
Language: engleski
Summary: During the period of air-raid alarms in Zagreb(September
1991) ,the influence of war-induced stress on the incidence and mortality
of acute coronary arter disease was investigated.Control periods were
September 1989 and September 1990.Among 2903 patients admitted to Emergency
Care Units,369(13%) were examined for suspected coronary artery
disease.During the same periods in 1989 and 1990,10% and 11% of acute
coronary artery disease patients were recorded,respectivelly.The percentage
of patients with myocardial infarction or unstable angina,admitted to
Coronary Care Units during September 1989,1990 and 1991,was 49%,50% and
55%,respectively.The number of Q myocardial patients admitted during
September 1991 was significantly higher than that recordedduring the same
period in 1990.The incidence and mortality patterns in acute coronary
artery disease patients were also examinedduring August,September and
October 1991.The peak incidence of acute coronary artery disease was found
in the first half of September,while the peak mortality in these patients
eas foundduring the second half of September.During the second half od
September of 1989,1990 and 1991,the mortality in Q myocardial patients in
Coronary Care Units,was 16,7%,15,2% and 23,8%,respectively.Besides the
war-induced stress,transportation of aour patients to shelters or inner
parts of the hospital caused additional stress,probably contributing to the
development of refractory malignant arrhythmia or heart failure.
Keywords: acute coronary artery disease,myocardial infarction,war,stress
- Type of paper
: Paper in journal
Title: Echocardiography in the diagnosis and treatment of
pulmonary embolism
- Authors:
- Nikolić-Heitzler, Vjeran (101623)
- Mihatov, Šime (97500)
Journal: Liječnički vjesnik
Number: Sup2
ISSN: 1330-4917
Volume: 117
Year: 1995
Pages: from 97 to 99
Number of references: 19
Language: hrvatski
Summary: A 58 year woman was admitted to this hospital because of
retrosternal paim followed by dyspnea which developed a few hours prior to
admission,and two week history of progressive intolerance of physical
effort.Echocardiography was done which revealed enlarged cavity of the
right atrium(59x54 mm) and right ventricle(46 mm) of ther
heart.Scintigraphy showed numerous triangular lung zones of sharply
desceased or completely absent perfusion.After the diagnosis of reccurent
pulmonary embolism,the patient was treated with intravenous heparin at a
dosage of 25000iu a day for 10 days.Dyspnea settled within 48 hours of
starting heparin,analysis of arterial blood gases became normal and the
general condition of the patient improved.A repeated echocardiogram showed
a significantly reduced dilatation ot the right atrium from 59x45 mm to
47x43 mm and decreased pulmonary hypertension from 110 mm Hg,on
admission,to 65 mm Hg.
- Type of paper
: Summary in proceedings
Title: Hyperdynamic syndrom induced by the war
- Authors:
- Nikolić-Heitzler, Vjeran (101623)
- Bergovec, Mijo (138132)
- Prpić, Hrvoje (145593)
- Stančić, V
- Mihatov, Šime (97500)
- Editors
- Čikeš, I.
Proceedings title: 1.Kongres Hrvatskog kardiološkog društva
Language: hrvatski
Place: Opatija
Year: 1993
Pages: from 4 to 0
Held: from 04/22/93 to 04/24/93
- Type of paper
: Summary in proceedings
Title: Incidence and hospital mortality of acute ischemic heart
disease among civilian in Zagreb city area during air-raid alarms
- Authors:
- Bergovec, Mijo (138132)
- Mihatov, Šime (97500)
- Prpić, Hrvoje (145593)
- Nikolić-Heitzler, Vjeran (101623)
- Batarelo, V
- Rogan, S.
- Sjerobabski, V.
- Gjurašin, M.
- GoldneV.,
- Čikeš, I.
- Editors
- Čikeš, I.
Proceedings title: 1.Kongres Hrvatskog kardiološkog društva
Language: hrvatski
Place: Opatija
Year: 1993
Pages: from 1 to 0
Held: from 04/22/93 to 04/24/93
- Type of paper
: Summary in proceedings
Title: Diagnostic singificance of endomyocardial biopsy od right
ventricle
- Authors:
- Ferenčić, Ž.
- Planinc, Danijel (153316)
- Jerić, Marijan (114021)
- Pagon, Lj.
- Nikolić-Heitzler, Vjeran (101623)
- Mihatov, Šime (97500)
- Editors
- Čikeš, I.
Proceedings title: 1.Kongres Hrvatskog kardiološkog društva
Place: Opatija
Year: 1993
Pages: from 10 to 0
Meeting: 1.Kongres Hrvstskog kardiološkog društva
Held: from 04/22/93 to 04/24/93
- Type of paper
: Summary in proceedings
Title: Prognostic value of hemodynamic parameters of left
ventricular function in five years folow-up after acute myocardial
infarction
- Authors:
- Delić-Brkljačić, D.
- Žigman, Miroslav (141166)
- Bergovec, Mijo (138132)
- Mihatov, Šime (97500)
- Editors
- Čikeš, I.
Proceedings title: 1.Kongres Hrvatskog kardiološkog društva
Language: hrvatski
Place: Opatija
Year: 1993
Pages: from 14 to 0
Meeting: 1.Kongres Hrvstskog kardiološkog društva
Held: from 04/22/93 to 04/24/93
- Type of paper
: Summary in proceedings
Title: Analysis of late potentials in acute ischemic heart
disease
- Authors:
- Batarelo, V
- Sjerobabski, V.
- Birtić, Krešimir (3784)
- Bergovec, Mijo (138132)
- Mihatov, Šime (97500)
- Editors
- Čikeš, I.
Proceedings title: 1. Kongres Hrvatskog kardiološkog društva
Language: hrvatski
Place: Opatija
Year: 1993
Pages: from 23 to 0
Meeting: 1.Kongres Hrvstskog kardiološkog društva
Held: from 04/22/93 to 04/24/93
- Type of paper
: Summary in proceedings
Title: Accuracy of assessment of the severity of aortic stenosis
by Doppler echocardiography(correlation with invasive method)
- Authors:
- Omčikus-Pevalek, Mirjana (97592)
- Jerić, Marijan (114021)
- Nikolić-Heitzler, Vjeran (101623)
- Planinc, Danijel (153316)
- Pagon, Lj.
- Mihatov, Šime (97500)
- Editors
- Čikeš, I.
Proceedings title: 1. Kongres Hrvatskog kardiološkog društva
Language: hrvatski
Place: Opatija
Pages: from 34 to 0
Meeting: 1.Kongres Hrvstskog kardiološkog društva
Held: from 04/22/93 to 04/24/93
- Type of paper
: Summary in proceedings
Title: Amrinone in the therapy of refractory heart failure
- Authors:
- Nikolić-Heitzler, Vjeran (101623)
- Prpić, Hrvoje (145593)
- Bergovec, Mijo (138132)
- Žigman, Miroslav (141166)
- Mihatov, Šime (97500)
- Omčikus-Pevalek, Mirjana (97592)
- Vukosavić, Đuro (96240)
- Editors
- Čikeš, I.
Proceedings title: 1.Kongres Hrvatskog kardiološkog društva
Language: hrvatski
Place: Opatija
Year: 1993
Pages: from 135 to 0
Meeting: 1.Kongres Hrvstskog kardiološkog društva
Held: from 04/22/93 to 04/24/93
- Type of paper
: Summary in proceedings
Title: Effective comparison of Thiopenthone and Propofol to the
respiration parameters and heart frequency during cardioversion
- Authors:
- Bergovec, Mijo (138132)
- Mihatov, Šime (97500)
- Editors
- Bergovec, Mijo (138132)
Proceedings title: Cardiologia Hungarica
Language: engleski
Place: Budapest, Mađarska
Year: 1995
Pages: from 4
Meeting: Alpe Adria Cardiology Meeting
Held: from 05/17/95 to 05/20/95
Summary: As the therapeutical method,elective cardioversion was used
to treat 24 pts with atrial fibrillation,including thiopenthone compared
with propofol as induction agents in anesthesia.In course of various time
sequences,the effects to respiration frequency ,tidal volume,oxygen
saturation and heart rate were observed during DC countershock.Statistical
method that has been used was nonparametric Mann-Whitney U-test.
Considerin this procedure,the results proved the existing of significant
differences between thiopenthone or propofol.Already during injection in
the first 30 seconds of thiopentone or propofol,statistically significant
differences are noticed in respiration frequency (ll.83+-l,75 vs
14.17+-3.l9,p=0.03);and ventilation "depth"(554.17+-101.04 vs
437.50+-111.04;p=0.03),two minutes after injection similar differences
showed in respiration rate(1o.33+-1.23 vs 12.00+-1.78;p=0.02);tidal
volume(512.50+-85.61 vs 429.17+-72.17),p=0.03)and oxygen saturation
(84.58+-6.4 vs 81.50+-3.53,p=0.03).heart rate considerably is different one
minute (lol.25+-18.31 vs 92.83+-43.10;p=0.04) as well as ten minutes after
cardioversion (95.92+-21.51 vs 79.92+-31.13;p=0.03).
We conclude that thiopenthone depress repiration less than propofol
does;so we prefer thiopenthone in practicng cardioversion.
- Type of paper
: Summary in proceedings
Title: Heart function in chronic alcoholism
- Authors:
- Nikolić-Heitzler, Vjeran (101623)
- Omčikus-Pevalek, Mirjana (97592)
- Bergovec, Mijo (138132)
- Mihatov, Šime (97500)
Proceedings title: 3nd Alpe Adria Cardiology Meeting
Language: engleski
Place: Budapest, Mađarska
Year: 1995
Pages: from 31
Meeting: Alpe Adria Cardiology Meeting
Held: from 05/17/95 to 05/20/95
Summary: The aim of this study was to investigate the influence of
chronic alcohol abuse on the heart function.The study carried on 54 male
manual workers,32 of them (Group A) were chronic alcoholics,aged
29-57.median 40.5 years,who had a history of alcoholconsumption pf more
than 100 g a day over a period of ten years.They were compared with 22
non-alcoholics(Group B),aged 29-56,median 38,5 years.None of the subjects
had palpitation,dyspnea,chest pain,and all were in sinus
rhythm.Non-invasive cardiac examination were carried out.The ejection
fraction (%) calculated from the M mode echocardiography in Group A was
42-70,median 62%,vs Group B 58-70,median 67%.(p=0.069).
Results at rest Group A Group B p
heart beat/min 70-150(98.5) 40-87(71) o.ooo1
systolic pressure/mm Hg 120-180(140) 110-150(130) 0.0014
diastolic pressure 80-120(95) 70-100(85) 0.004
Results at maximal exercise test
heart beat/min 121-188(170.5) 121-190(180) 0.0317
systolic pressure 120-225(180) 150-210(160) 0.0045
diastolic pressure 80-135(102.5) 90-110(100) NS
metabolic equivalent 5.8-12.2(10.8) 9.4-12.2(10.8) NS
duration of test/min 4.1-12-1(10) 9.0-12-1(10) NS
Conclusion:Although Group A had a significantly lower ejection fraction and
a higher heart frequency and blood pressure at the beginning of the
exercise test,there is no statistically significant difference in stress
tolerance between Group A and b.
- Type of paper
: Ph.D.
Title:
Faculty: Medicinski u Zagrebu
Author: MIHATOV ŠIME
Date of defense: 11/02/95
Language: hrvatski
Number of pages: 159
Summary: Laboratory findings and some therapeutic approach of 94
severe war wounded,treated in Surgical ICU of "Sisters of Mercy"
University Hospital in Zagreb were analysed.General data about types and
causes of wounded indicate that there are no differences when compared with
wounded from other wars(Vietnam,Israel).RBC count,amoong laboratory
analyses,was relatively high according to the severity of wounds.The main
cause was,probably,that most of wounded had injures caused by shrapnel,low
velocity and energy missiles.Tissue destruction caused by shrapnel is less
than those cause by bullets.Contrary,huge amounts of blood and fluids given
to wounded during resuscitation and operations were necessary.Hypokalemia
was marked,unexpected,problem.Additionally,it correlated positively and
statistically significant with pH and base excess.It was neurohumoral
consequence od shock state.Most severe wounded had reperfusion liver
injury.Among coagulation tests,low number of platelets was marked.Dopamin
prevention of ARF was of no value.The best ARF prevention is,as soon as
possible,infucion of enough amounts of fluid,to establish good tissue
perfusion.Prophylactic use of antibiotics was succesful.Stress-ulcer
prevention with ranitidin was good,but caused relatively high proportion of
pneumonia.Catabolism was high,much higher than in civil trauma.Special care
had to be focused on parenteral and enteral nutrition.
- Type of paper
: M.A.
Title: Prognostic value of hemodynamic parameters of left
ventricular function in five- years survival after acute myocartdial
infarction
Faculty: Prirodoslovno-matematički u Zagrebu
Author: MIHATOV ŠIME
Date of defense: 12/17/92
Language: hrvatski
Number of pages: 67
Summary: Predictive value of several hemodynamic parameters of LV
functionin five-years survival after AIM were examined in 70 pts.The aimof
analysis was to determine the predictive value of globalEF,endsystolic and
enddiastolic volume,determined by radionuclidestudies in early phase,as
wall as infarct size determined byenzymes and by Selvester QRS scoring
system upon five-yearssurvival of these patients.Five years survival curves
point that91.4% of pts have survived 1 year,86.6% 2 years,83.6%
3years,80.6% 4 years.Among those who died because of cardiaccauses 50% have
died after 18 months.Multiple regression analysisindicates that EF
represents by far the most significantpredictive factor among observed
variables.
The global EF determined by radionuclide studies in subacutephase has,among
the tested indicators,the most importantprognostic value in five-years
survival after AIM.
Keywords: myocardial infarction,prognosis,global ejection fraction,
- Type of paper
: M.A.
Title: The value of following up the concentration of procollagen
III peptide in assessment of the scar formation after acute myocardial
infarction
Faculty: Medicinski u Zagrebu
Author: MIHATOV ŠIME
Date of defense: 05/03/94
Language: hrvatski
Number of pages: 45
Summary: The formation of the scar after myocardial infarction(MI)
means healing and health.Procollagen III peptide (PIIIP) is a serum marker
of the fibroblasts activity,collagen type III secretion and scar
formation.The aim of this study was to establish:if the serum PIIIP
concentration is raised after MI in the period of maximal fibroblasts
proliferation and activity,if the PIIIP concentration is normalized six
weeks after MI,if there is a correlation between PIIIP and maximal post
infarction creatinphosphokinase(CK) values and if the PIIIP values can be
connected to the MI complications that are depending of the scar quality.
The study included 40 healthy serum donors,and 41 patients with MI.PIIIP
was measured at admission (within 8 hours of the onsetof symptoms),14 days
and 6 weeks after the MI with double sandwich test using RIA-gnost set
Procollagen-III-Peptide,Behringwerke AG.The difference significance between
measured variables was tasted with Student t test,and the correlation with
Pearson's correlation coeficient.
This results showed that the healthy donors had serum PIIIP concentration
within normal limits given by the RIA-gnost set producer.Within 8 hours of
the MI onset,all the patients had normal PIIIP.After 14 days,PIIIP was
significantly rised compared to the acute phase of MI (p<0.01).In two
patients who developed post infarction aneurysm it remained within normal
limits.Six weeks after MI,in the patients free of symptoms,PIIIP returned
to normal values.In 7 patients who had frequent post infarction stenocardia
PIIIP remained eleveted.
The results of this study showed that PIIIP is a good marker of post
infarction scar quality and quantity.It could be used in the clinical work
to discover patients with week capabilities for scar formation after MI and
therefor at greater risk to develop postinfarction complications which
depend on scar quality.
- Type of paper
: Mentorship
Title: Prognostic value of parameters of left ventricular
function in five-years survival after acute myocardial infarction
Faculty: Prirodoslovno-matematički u Zagrebu
Mentor: MIHATOV ŠIME
Date of defense: 12/17/92
Number of pages: 67
Author: Delić-Brkljačić D.
Degree level: M.A.
- Type of paper
: Mentorship
Title: Laboratory and clinical findings in severe war wounded as
a basis for therapy in minimal conditions of medical care
Faculty: Medicinski u Zagrebu
Mentor: MIHATOV ŠIME
Date of defense: 11/02/95
Number of pages: 159
Author: Perić mr.sc. Mladen
Degree level: Ph.D.
- Type of paper
: Mentorship
Title: Diagnosis and natural history of the amyloidosis of the
heart
Faculty: Medicinski u Zagrebu
Mentor: MIHATOV ŠIME
Date of defense: 07/06/95
Number of pages: 31
Author: Šipić dr.med. Tomislav
Degree level: D.A.
- Type of paper
: Mentorship
Title: The value of following-up the concentration of Procollagen
III Peptide in assessment of scar formation after acute myocardial
infarction
Faculty: Medicinski u Zagrebu
Mentor: MIHATOV ŠIME
Date of defense: 05/03/94
Number of pages: 46
Author: Kolevska Kaniški mr.sc. Tatjana
Degree level: M.A.