Summary: The aim of this research was to assess the influence of the
size of myocardial infarction on cardiac function,the efficacy of
thrombolytic therapy of acute myocardial infarction and precise evaluation
of the cardiac function in patients with myocardial infarction in the acute
and chronic phase,using multiparametric approach.
Research goals: The aim of this investigation was to analyze the
influence of ischemic heart disease on the cardiac function,how to
optimally influence the coarse of the disease with therapy and
preservation of cardiac function,as well as precise estimation of cardiac
function what is the cornerstone of assessment of work capacity.
Investigation was performed in sveral directions: 1.-investigation of the
succes of fibrinolytic treatment of acute myocardial infarction,and the
assessment of the cardiac function in acute and chronic phase in comparison
with other methods, 2.-investigation of electrocardiographic and
vectocardiographic signs of previous myocardial infarction and infarction
size, 3.-investigation of the relationship between the size of myocardial
infarction and diastolic function, 4.-investigatio of global and regional
disturbances of the left ventricular function in patients with myocardial
infarction, The expected scientific contribution of this investigation is
in better understanding of heart pump function during acute and chronic
phase of myocardial infarction,and better knowledge of the efficiency of
different therapeutic approach. The results of this investigation approve:
-precise estimation of exercise tolerance in everyday or professional
life,the estimation of working capacity,and the choice of the most optimal
rehabilitation treatment -evaluation of therapeutic treatment which are of
the most interest in the treatment of ischemic heart disease
-rationalisation of diagnostic procedures in the assessment of cardiac
function concidering a wide spectrum of cardiologic techniques,with purpose
to eliminate expnsive or invasive with more simple and non invasive
procedures. Other information about the project.