SVIBOR - Project code: 3-01-227

MINISTRY OF SCIENCE AND TECHNOLOGY

Strossmayerov trg 4, HR - 10000 ZAGREB
tel.: +385 1 459 44 44, fax: +385 1 459 44 69
E-mail: ured@znanost.hr

SVIBOR

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Project code: 3-01-227


Hemodynamics and transfer factor in interstial pulmonary diseases


Main researcher: TOCILJ, JADRANKA (20612)


Assistants
Type of research: applied
Duration from: 01/01/91. to 01/01/94.
Papers on project (total): 32
Papers on project quoted in Current Contents: 22
Institution name: Bolnica "Firule", Split (141)
Department/Institute: Department of pulmonary diseases, Respiratory Laboratory
Address: Spinčićeva 1
City: 21000 - Split, Croatia
Communication
Phone: 385 (0)021/515-055lokal439
Summary: The aim of this investigation was to define new diagnostic algorithms for early diagnosis and follow-up of patients with interstitial lung diseases. Examinees were comprised of asbestos-axposed workers (N=400), patients with asbestosis (N=45), sclerodermia (N=23) and sarcoidosis (N=30). Evaluating protocol included longitudinal measurements of lung function, chest x-ray and lung CT, quntified by our own method, arterial blood gases and dynamic radionuclide angiography, analyzed by our own methods. It was found that the early phase of these diseases is characterized by transient increase in lung transfer factor for CO (TLCO), what is the sole noninvasive sensitive paramater in early alveolitis.

Keywords: interstitial lung diseases, lung transfer factor, radioangiography, high resolution CT, arterial blood gases, asbestosis, sarcoidosis, sclerodermia

Research goals: The goal of this investigation was to improve noninvasive diagnostics and evaluation of the interstitial lung diseases (ILD). A definition of a simple diagnsotic protocol for early detection, follow-up and objective evaluation of working ability in patients with ILD is expected.

COOPERATION - INSTITUTIONS


  1. Name of institution: Prirodoslovno-matematički fakultet
    Type of institution: University/Faculty
    Type of cooperation: Systematic exchange of information
    City: 21000 - Split, Croatia

  2. Name of institution: Medicinski fakultet
    Type of institution: University/Faculty
    Type of cooperation: Joint publishing of scientific papers
    City: 21000 - Split, Croatia

  3. Name of institution: Tehnološki fakultet
    Type of institution: University/Faculty
    Type of cooperation: Systematic exchange of information
    City: 21000 - Split, Croatia
Other information about the project.
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Last update: 10/12/95
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