- Type of paper
: Paper in journal
Title: Laboratory diagnosis of Lyme disease
- Authors:
- Tkalec-Makovec, Nevenka (91602)
- Nemet, Branka (99322)
Journal: ACTA MEDICORUM
Number: 1
ISSN: 0350-1167
Volume: 17
Year: 1991
Pages: from 53 to 56
Number of references: 18
Language: hrvatski
Summary: The laboratory methods for diagnosis of Lyme disease are
described. The most accurate diagnosis of Lyme disease isachieved by
culture demonstration of Borrelia burgdorferi, bat serologic methods are
the mainstay of diagnosis in all threeclinical stages of disease.
The methods used for the diagnosis of Lyme disease in the world
and the methods used in Microbiological laboratory of Medical
centre Varaždin are presented.
Keywords: Lyme disease, Laboratory diagnosis
- Type of paper
: Paper in journal
Title: Indirect immunofluorescence assays and hemagglutination in
diagnosis of Lyme disease
- Authors:
- Tkalec-Makovec, Nevenka (91602)
- Nemet, Branka (99322)
Journal: ACTA MEDICORUM
Number: 1
ISSN: 0350-1167
Volume: 18
Year: 1992
Pages: from 75 to 78
Number of references: 10
Language: hrvatski
Summary: In our investigations were included 100 healthy persons and
100
patients with suspection on clinical picture with Lyme disease.
Indirect Immunofluorescence Method (IFA) and IndirectHemagglutination (IHA)
are serological methods used in diagnosisof Lyme disease. According to our
experiences HA is more specificand the technic procedure is easier and more
rapid and practicalin screening test for identification of initial titer.
IFA is asubtile demand in diagnosis of Lyme disease.
Keywords: Lyme disease, indirect Immunofluorescence, Hemagglutination
- Type of paper
: Paper in journal
Title: Lyme borreliosis in the region of Varaždin
- Authors:
- Plešnar, Antonio (91602)
- Tkalec-Makovec, Nevenka (91602)
Journal: ACTA MEDICORUM
Number: 1
ISSN: 0350-1167
Volume: 18
Year: 1992
Pages: from 79 to 81
Number of references: 5
Language: hrvatski
Summary: In the region of Varaždin 269 patients suspected on Lyme
disease
were examined anamnestically, clinically and serologically. 149
patients were from district of Varaždin and the other were from
Ivanec, Novi Marof, Ludbreg and Čakovec. 110 patients had serological
positive results and out of the number 59 had pathognomonic increase of
titer. On the basis of suspected clinical pictures and serologic positive
patients on Borrelia burgdorferi in the region of Varaždin Lyme disease is
present and this induces additional investigations.
Keywords: Lyme disease, Varaždin region
- Type of paper
: Paper in journal
Title: Economic data abaut diagnosis and therapy of Lyme disease
in NorthwestCroatia
- Authors:
- Tkalec-Makovec, Nevenka (91602)
- Đerahović, Mladen
- Martinec, Biserka
- Tkalec, Stjepan (157563)
- Plešnar, Antonio (91602)
- Golubić, Dragutin (159872)
- Đerahović, Mladen
- Smoljan, Ines
- Pospiš, Miroslav (125082)
- Pavliček, Ivan (165604)
- Majski-Cesarec, Slavenka
- Habulan, M.
- Kučko, A.
Journal: ACTA MEDICORUM
Number: 1
ISSN: 0350-1167
Volume: 18
Year: 1992
Pages: from 83 to 98
Number of references: 12
Language: hrvatski
Summary: During the last two years serologic methods for diagnosis
of Lyme
disease (LD) have been used. On this basis we tried to solve the
diagnostic problem in patients with unclear clinical pictures in
the region of Varaždin and Čakovec. 660 specimen from 470patients clinical
suspected for LD were analysed byHemagglutination (HA) and by method of
IndirectImmunofluorescence (IFA). The economic data are presented in
DEM.The multidisciplinary approach to LD are emphasized in theconclusion,
and the economic benefit of early and fast diagnosticprocedure.
Keywords: Lyme disease, Diagnosis, Therapy, Economic approach
- Type of paper
: Paper in journal
Title: Lyme borreliosis in Northwest Croatia - Our experiences
- Authors:
- Tkalec-Makovec, Nevenka (91602)
- Golubić, Dragutin (159872)
Journal: ACTA MEDICORUM
Number: 1
ISSN: 0350-1167
Volume: 18
Year: 1992
Pages: from 99 to 101
Number of references: 10
Language: hrvatski
Summary: In this report Borrelia burgdorferi is described the cause
of
Lyme disease according to taxonomy, morphology and antigenic
viewpoint. The most adequate way of antibiotic work in somestages of Lyme
disease is presented. The advantages of rapid serologic diagnostic
procedure and also the importance Borrelia
burgdorferi cultivation emphasised. The economic analysis shows
that it is most important to discover and treat the disease on
the first stage when the clinical picture is easy recognizable
compared to difficult recognisable and more expensive treatment
in late stage.
Keywords: Lyme disease
- Type of paper
: Paper in journal
Title: Clinical, epidemiological and serological characteristics
of Lyme borreliosis in Međimurje
- Authors:
- Golubić, Dragutin (159872)
- Tkalec-Makovec, Nevenka (91602)
Journal: ACTA MEDICORUM
Number: 1
ISSN: 0350-1167
Volume: 18
Year: 1992
Pages: from 103 to 110
Number of references: 22
Language: hrvatski
Summary: Clinical, epidemiological and serological characteristics
of thefirst cases of Lyme borreliosis in Međimurje region are described.
Forty patients with Lyme borreliosis are included in this
investigation. The diagnosis was in the course of 1991 and 1992
established in the polyclinical section of infectology in Medical
center Čakovec. The diagnosis of Lyme borreliosis has been basedon
epidemiological data about tick bite or other hematophagic
insect, clinical picture, course of disease and serologicanalyses. Serum of
patients has been analysed on Borreliaburgdorferi by indirect
immunofluorescence and hemagglutinationtests, which was 57,7% of patients
positive.
Keywords: Lyme borreliosis, Međimurje
- Type of paper
: Paper in journal
Title: Microbiologic investigations of Lyme disease
- Authors:
- Tkalec-Makovec, Nevenka (91602)
Journal: ACTA MEDICORUM
Number: 1
ISSN: 0350-1167
Volume: 18
Year: 1992
Pages: from 111 to 113
Number of references: 7
Language: hrvatski
Summary: In this article a brief historical report of Lyme disease
causesand syptoms dyscovery is given. The morphology, metabolism andantigen
characteristics of Borrelia burgdorferi are analysed in order to a more
adequate clinical interpretation of the disease stage. Didactic
classification of Lyme disease on stages is givedbecause of a great variety
in clinical picture and similar symptoms. The aim of work is to emphasise
the importance of early recognition of disease symptoms, to take the sample
for isolation of cause and to determ one the titar of antibody on antigen
of Borrelia burgdorferi. The cooperation of clinical physican and
microbiologist give the appropriate diagnosis.
Keywords: Lyme disease, Microbiologic investigation
- Type of paper
: Paper in journal
Title:
- Authors:
- Rijpkema, S.
- Golubić, Dragutin (159872)
- Verbeek-De Kruif, N.
- Schellekens, J.
Journal: Journal of Experimental an Applied Entomology
Language: engleski
Summary: The analysis by PCR has shown that B. burgdorferi sensu
lato DNA was positive in 56 (45%) of 124 field-collected ticks in five
locations of northern Croatia. Four genomic groups were identified: B.
afzelii (n=26), B. garinii (n=5), group VS116 (n=5) and B. burgdorferi
sensu stricto (n=1). Eight ticks contained B. burgdorferi sensu lato wich
could not be typed. The presence of B. afzelii and B. garinii in ticks
agrees with cutaneous and neurological manifestation of Lyme borreliosis
found locally. The occurrence of group VS116 in ticks collected in northern
Croatia, infers that this genomic group is well established in European I.
ricinus.
Keywords: Borrelia burgdorferi
- Type of paper
: Paper in proceedings
Title: Indirect immunofluorescence assays and hemagglutination in
diagnosis of Lyme disease
- Authors:
- Tkalec-Makovec, Nevenka (91602)
- Nemet, Branka (99322)
Proceedings title: Dijagnostički postupci u kliničkoj obradi infektoloških bolesnika.
Language: hrvatski
Place: Zagreb
Year: 1993
Pages: from 41 to 44
Meeting: Hrvatski stručno-znanstveni sastanak infektologa, mikrobiologa i epidemiologa
Held: from 05/21/93 to 05/22/93
Summary: Indirect immunofluorescence and hemagglutination are
serologicalmethods used in diagnosis of Lyme disease. According to
ourexperiencese IHA is more specific and IFA is more sensitivemethod in
diagnosis of Lyme disease.
Keywords: Lyme disease, IHA, IFA
- Type of paper
: Paper in proceedings
Title: Lyme borreliosis in the region of Varaždin
- Authors:
- Plešnar, Antonio (91602)
- Tkalec-Makovec, Nevenka (91602)
- Editors
- Petričević, Ivan
Proceedings title: Dijagnostički postupci u kliničkoj obradi infektoloških bolesnika.
Language: hrvatski
Place: Zagreb
Year: 1993
Pages: from 147 to 151
Meeting: Hrvatski stručno-znanstveni sastanak infektologa, mikrobiologa i epidemiologa
Held: from 05/21/93 to 05/22/93
Summary: In the region of Varaždin 269 patients suspected on Lyme
diseasewere examined anamnestically, clinically and serologically. Onthe
basis our results are emphasised in the region of VaraždinLyme disease is
present and dies induces additionalinvestigations.
Keywords: Lyme disease, Region of Varaždin
- Type of paper
: Summary in proceedings
Title: About Lyme disease in the Region of Varaždin and Međimurje
- Authors:
- Tkalec-Makovec, Nevenka (91602)
- Tkalec, Stjepan (157563)
- Golubić, Dragutin (159872)
Proceedings title: 3. hrvatski kongres kliničke mikrobiologije : Knjiga sažetaka
Language: hrvatski
Place: Zagreb
Year: 1993
Pages: from 45 to 45
Meeting: 3. hrvatski kongres kliničke mikrobiologije
Held: from 10/13/93 to 10/15/93
Summary: During two years it was analysed by serological methods
996samples of 703 clinical suspect patients on Lyme disease. Diseaseis
present in the boef regions, and for the better diagnose isnecesary
determine pathognomonic titer of specific antibodies toBorrelia burgdorferi
of regional population.
Keywords: Lyme disease, Varaždin, Međimurje
- Type of paper
: M.A.
Title: Lyme borreliosis in North-West Croatia
Faculty: Medicinski fakultet Zagreb
Date of defense: 04/27/95
Language: hrvatski
Number of pages: 63
- Type of paper
: Radio broadcast
Title:
- Authors:
- Tkalec-Makovec, Nevenka (91602)
Radio station: Hrvatski radio, Radio Varaždin
Name of emission (broadcast): Informativna emisija
Year: 1991
- Type of paper
: Radio broadcast
Title:
- Authors:
- Tkalec-Makovec, Nevenka (91602)
Radio station: Hrvatski radio, Radio Varaždin
Name of emission (broadcast): Informativna emisija
Year: 1993
- Type of paper
: TV broadcast
Title:
- Authors:
- Golubić, Dragutin (159872)
TV station: TV Čakovec
Name of emission (broadcast): Informativna emisija
Year: 1993
- Type of paper
: Manuscript
Title:
- Authors:
- Tkalec-Makovec, Nevenka (91602)
Language: hrvatski
Other:
- Type of paper
: Other
Title:
- Authors:
- Bregović, Antica
- Tkalec-Makovec, Nevenka (91602)
Type of work: Izložba u Gradskom muzeju Varaždin, svibanj-listopad 1991.
- Type of paper
: Other
Title:
- Authors:
- Tkalec-Makovec, Nevenka (91602)
- Golubić, Dragutin (159872)
Type of work: Predavanje u Hrv. liječničkom zboru, podružnica Čakovec, 20. listopada 1992.
- Type of paper
: Other
Title:
- Authors:
- Tkalec-Makovec, Nevenka (91602)
Type of work: Predavanje u HLZ, podružnica Varaždin, 8. prosinca 1992.
- Type of paper
: Other
Title:
- Authors:
- Tkalec-Makovec, Nevenka (91602)
Type of work: Predavanje u organizaciji Ogranka Matice hrvatske Varaždin, 18. ožujka 1993.
- Type of paper
: Other
Title:
- Authors:
- Tkalec-Makovec, Nevenka (91602)
- Tkalec, Stjepan (157563)
- Golubić, Dragutin (159872)
Type of work: Referat na osnivačkom sastanku ELBF u Engleskoj/Cambridge 10.12.1993.
- Type of paper
: Other
Title: Clinical and microbiological aspects of Lyme borreliosis
in North-West Croatia
- Authors:
- Golubić, Dragutin (159872)
- Tkalec-Makovec, Nevenka (91602)
- Tkalec, Stjepan (157563)
Type of work: Izvješće na VI International conference... - Bologna/Italy, June 19-22. 1994.
Language: engleski
Summary: 1288 samples of clinical suspect patients on Lyme disease
in Nort-West Croatia have been analysed by microbiological methods. Out of
all tested patients, in 1/4 is confirmed Borrelia burgdorferi as on
etiological agens, Lyme borreliosis as main disease had 1/8 of patients and
1/16 as secundary disease.
Keywords: Lyme borreliosis, diagnosis, clinic
- Type of paper
: Other
Title: Where are we with the diagnostic of Lyme disease in the
North-West Croatia?
- Authors:
- Tkalec-Makovec, Nevenka (91602)
- Tkalec, Stjepan (157563)
- Golubić, Dragutin (159872)
- Plešnar, Antonio (91602)
Type of work: Izvješće na II. znanstv. sastanku... - Pula, 8-11.06.94. - v. rubriku Ostalo
Language: hrvatski
Summary: Diagnosis of Lyme disease is described. Diagnosis of the
disease is based on clinical-epidemiological and serological criteria. Our
results indicate that 20% in obs diagnosis has been changed with the Lyme
disease.
Keywords: Lyme disease, diagnostik
Other: II. Hrvatski znanstveni sastanak infektologa, mikrobiologa i
epidemiologa. - Pula, 8. do 11. lipnja 1994.
- Type of paper
: Other
Title:
- Authors:
- Golubić, Dragutin (159872)
- Maksimović, N.
- Pavčec, Lj.
- Knapić, S.
- Hlavinkova-Djebi, M.
- Chamae, R.
Type of work: Izvješće na simpoziju u Portorožu 13-15. svibnja 1995. - v. rubriku Ostalo
Language: engleski
Summary: A three year followb up of 73 Lyme borreliosis patients
with facial palsy were analysed. Age range were 6-87 years and mean age
were 38 years. The majority of patients were treated 14 days with
doxycyclin with very good results (symptoms complete ceased). Penicillin
and azithromycin were used on children under 12 years. The authors
emphasized 14 days doxycyclin therapy of
facial palsy patients for initiated therapy. If symptoms do not cesed,
usage of second cyclus with doxacyclin for 14 days or better parenteral
ceftriaxon, is indicated.
Keywords: Lyme borreliosis, facial palsy, treatment
Other: Symposium on the therapy and prophylaxis for Lyme
borreliosis.- Portorož / Slovenia, May 13-15, 1995. - Organized by Gerold
Stanek, Vienna & Franz Strie, Ljubljana
- Type of paper
: Other
Title: Lyme borreliosis in North-West Croatia
- Authors:
- Plešnar, Antonio (91602)
Type of work: Magistarski rad (*usp. i podatke pod: Magistarski rad!)
Language: hrvatski
Summary: 1033 patients with Lyme borreliosis symptoms (1033) were
examined from 1990 to 1994. 595 were hospitalized and 438 were treated in
the primary care unit. Positive anamnesis was proved in 298 patients
(28,84%), 629 (60,89%) patients had positive clinical picture, 311 (30,12%)
had positive microbiological tests while definitive diagnosis was proved in
206 (19,94%) patients.
1458 specimens were tested for microbiological diagnosis (1406 from serum,
43 from liquors and 8 from knee punctation).
Keywords: Lyme borreliosis, North-West Croatia
Other: (Usporedi i podatke u rubrici: Disertacije!)
- Type of paper
: Other
Title:
- Authors:
- Kelemenić, Karmen
Type of work: Diplomski rad. -Sveučilište u Zagrebu, Prirodosl.-matemat. fakultet, 1994.
Language: hrvatski
Other: Sveučilište u Zagrebu : Prirodoslovno-matematički fakultet.-
Odjel: biološki, Smjer: prof. biologije, Smjer: dipl. ing. biologije -
ekologija.- Opseg rada: 51 str.- Zagreb, 1994.
- Type of paper
: Other
Title:
- Authors:
- Vuković, Vedrana
Type of work: Maturalni rad.- Gimnazija u Varaždinu, šk. god. 1994/95.
Language: hrvatski
Other: Mentor: Biserka BOGADI, prof.- Razredni odjel: 4a.- U
Varaždinu, 09. svibnja, 1995.- Opseg rada: 24 str. i 3 tablice kao
privitak.
- Type of paper
: Other
Title:
- Authors:
- Pongrac, Tomislav
Type of work: Maturalni rad.- Gimnazija u Varaždinu, šk. god. 1994/95.
Language: hrvatski
Other: Mentor: Biserka Bogadi, prof.- Razredni odjel: 4.h.- Opseg
rada: 19 str.
- Type of paper
: Other
Title:
- Authors:
- Andrović, Alen
- Mikulić, Valentina
Type of work: Učenički rad (8. razr.).- Osnovna škola Trnovec.-
Other: Mentori: Dr. sc. Nevenka Tkalec-Makovec, dr. med., Biserka
Vujošević, nastavnik likovne kulture, Štefanija Jurašković, nastavnik
biologije.- Trnovec, 19. ožujka 1994.- Opseg: 18 str. i 5 privitaka
