EPIDERMAL CHANGES IN THE PATIENTS TREATED WITH PHOTOTHERAPY
Main researcher
: DOBRIĆ, IVAN (10082) Assistants
BARIČEVIĆ, BRANKO (182254)
PALJAN, DAMIR (34691)
PAVIČIĆ, ŽELJKO (100060)
BASTA-JUZBAŠIĆ, ALEKSANDRA (70235)
ŠKRINJAR, LJUBOMIR (92965)
STANIMIROVIĆ, ANDRIJA (171581)
Type of research: applied Duration from: 10/10/91. to 10/10/94. Papers on project (total): 18
Papers on project quoted in Current Contents: 1
Institution name: Medicinski fakultet, Zagreb (108) Department/Institute: Department of Dermatovenerology, Zagreb Clinical Hospital and Zagreb University School of Medicine Address: Šalata 4, 41000 Zagreb, Croatia City: 10000 - Zagreb, Croatia
Communication
Phone: 385 (0)41 - 271 - 085
Fax: 385 (0)41 271 -085
Summary: Psoriasis is a very often skin disease.Unfortunately,the
disease has in most cases a lifelong course.According to some statistical
analyses about 5% of all dermatologycal patients are suffering from some
form of psoriasis. In view to the fact that the etiology of psoriasis is
not satisfactory examined,causal treatment does not exist. However,some of
succesfull methods of treatment which can result with a longer remission is
the use of ultraviolet irradiation (PUVA, UVB).Although both,PUVA and UVB
are giving a positive result (regulation of the epidermopoesis), it is
necessary to answer the following questios:1.for how long is it possible to
use these methods of therapy; 2.can the above mentioned methods of
treatment cause the skin precanceroses, carcinomas as well as malignant
melanomas; and 3.how the above mentioned methods of treatment can normalise
a process of keratinisation. To find the answers to these questions, about
60 patients suffering from psoriasis, as well as 5 healthy persons
(volunteers -control group ) will be examined.
Research goals: The purpose of this work is an attempt to answer the
following questions;1.for how long is it possible to use these methods of
therapy; 2.can the abowe mentioned methods of treatment cause the skin
precanceroses,carcinomas, as well as malignant melanomas, and 3.how the
above mentioned methods can normalise a process of keratinisation?
COOPERATION - INSTITUTIONS
Name of institution
: Dermatologische Klinik und Poliklinik
Ludwig - Maximilians - Universitat Munchen Type of institution: International organization City: Munchen, Deutchland
Name of institution
: Klinik und Poliklinik fur Dermatologie
Klinikum Universitat Regensburg Type of institution: International organization City: Regensburg, Deutchland
OTHER ACHIEVEMENTS
Name
: Deutcher Akademischer Austauchdienst (DADD),
1.10.-31.12.9.1993. Tema:Morphologische Verenderungen von keratinozyten und
Melanozyten in gesunder und psoriatischer Haut nach Bestrahlung mit
UVB-Licht und PUVA. Stipendiju je dobio Dr.Baričević, suradnik Type of achievement: Other Other information about the project.