- Type of paper
: Paper in book
Title: Prevention of the vertical transmission of hepatitis B
virus - the report for 1991 and 1992
- Authors:
- Capar, Marijan (110263)
- Kosić-Andrašević, Viktorija (85181)
- Raguž, Ljubica
- Mahulja-Stamenković, Vesna
- Žužek, Adele (188646)
- Dujmović, Antonija
- Milevoj-Ražem, Mirna
- Ljutić, Slavica
- Popić, Goran (162581)
- Editors
- Capar, Marijan (110263)
- Popić, Goran (162581)
- Murr, Gjuro (110241)
- Povrzanović, Igor (62161)
- Poretti, Daniela (134760)
- Peršić, Lino (85361)
Publisher: Opća bolnica Pula, Znanstvena jedinica
ISBN: 953-96007-1-5
Year: 1994
Pages: from 189 to 202
Number of references: 39
Language: hrvatski
Summary: During the first two years of the three years long
prospective study in the Istra and Primorje-Gorski Kotar counties, Croatia,
10627 newborns were born. Prenatal screening for hepatitis B (HB) infection
was carried out in all pregnant women, and 107 (1%) of them were HB surface
antigen (HBsAg) positive. 106 children from HBsAg positive mothers were
given appropriate intramuscular dose of hepatitis B immunoglobuline (HBIG)
and 20 Šg recombinant hepatitis B virus (rHBV) vaccine in the maternity
ward. The second and the third dose of rHBV vaccine were given 1 and 6
months after the first one. On the first control 1 month after birth all
controlled children (94 from 106 passive and active vaccinated) were HBsAg
negative and all but one anti-HBs positive; only at six months of age this
anti-HBs negative boy has been anti-HBs positive at preventive level of 11
IU/L anti-HBs. After the vaccination in maternity ward 12 children (11.3%)
did not come to control for various reasons. From cohort of 106 passive and
active vaccinated children in the maternity ward 64 (60.4%) were completely
vaccinated three times and all of them were at the age of 6 months HBsAg
negative and anti-HBs positive. Geometric mean titre (GMT) of anti-HBs were
in 51 children below 1000 IU/L (11 to 857 IU/L), in 9 above 1000 IU/L and
in 4 we do not have quantitative results of anti-HBs positive serums; the
anti-HBs titres did nit significantly differ (p>0.05) between breast-fed
and bottle-fed children. The side effects have been observed 9 times during
the 369 injections (2.4%); they were one day elevated temperature to 38.2ř
C and/or transient mild inflammation at the injection site. The historic
risk factors for HBV infection, as defined by USA Centers for Disease
Control were found in 43% HBsAg positive women and that confirm the need
for screening of all pregnant women for HBsAg.
Keywords: hepatitis B,prenatal screening,passive and active immunisation,newborn
- Type of paper
: Paper in journal
Title: Prevention of vertical transmission of hepatitis B
infection - the preliminary report about the first results of collaborative
study (Rijeka,Pula)
- Authors:
- Capar, Marijan (110263)
- Kosić-Andrašević, Viktorija (85181)
- Raguž, Ljubica
- Mahulja-Stamenković, Vesna
- Žužek, Adele (188646)
- Dujmović, Antonija
- Milevoj-Ražem, Mirna
- Ljutić, Slavica
- Popić, Goran (162581)
Journal: Liječnički Vjesnik
ISSN: 0024-3477
Volume: 113
Year: 1991
Pages: from 8 to 8
Language: hrvatski
- Type of paper
: Paper in journal
Title: Prevention of transmission of hepatitis B virus from HBsAg
positive mothers to their newborns
- Authors:
- Capar, Marijan (110263)
- Kosić-Andrašević, Viktorija (85181)
- Raguž, Ljubica
- Mahulja-Stamenković, Vesna
- Žužek, Adele (188646)
- Milevoj-Ražem, Mirna
- Dujmović, Antonija
- Ljutić, Slavica
- Popić, Goran (162581)
Journal: Paediatria Croatica
ISSN: 1330-1403
Volume: 37
Year: 1993
Pages: from 64 to 64
Language: hrvatski
- Type of paper
: Paper in journal
Title: Hepatitis Bs antigen positive pregnant women, active and
passive protection of their newborns and breast feeding
- Authors:
- Capar, Marijan (110263)
- Kosić-Andrašević, Viktorija (85181)
- Popić, Goran (162581)
- Mahulja-Stamenković, Vesna
- Žužek, Adele (188646)
- Milevoj-Ražem, Mirna
- Ljutić, Slavica
- Raguž, Ljubica
- Dujmović, Antonija
Journal: Paediatria Croatica
Number: 1
ISSN: 1330-1403
Volume: 37
Year: 1993
Pages: from 5 to 11
Language: engleski
- Type of paper
: Paper in journal
Title: The need and value of routine screening of all pregnant
women for hepatitis B surface antigen
- Authors:
- Capar, Marijan (110263)
- Kosić-Andrašević, Viktorija (85181)
- Popić, Goran (162581)
- Raguž, Ljubica
- Mahulja-Stamenković, Vesna
- Žužek, Adele (188646)
- Dujmović, Antonija
- Milevoj-Ražem, Mirna
- Ljutić, Slavica
Journal: Acta Medica Croatica
Number: 4-5
ISSN: 1330-0164
Volume: 49
Year: 1995
Pages: from 161 to 164
Number of references: 24
Language: engleski
Summary: A prospective study was performed to determine whether the
risk factors for hepatitis B, proposed by Centers for Disease Control
(CDC), USA, are reliable predictors for the hepatitis B surface antigen
(HBsAg) carrier state in an obstetric population. In the period between
January 1, 1991 and December 31, 1992, all pregnant women from
geographically defined areas of the Istra and Primorje-Gorski Kotar
counties, Croatia, were routinely screened for hepatitis B surface antigen
(HBsAg). Among 10,627 pregnant women, 107 (1%) HBsAg positive cases were
registered. History risk factors recommended by CDC were recorded in 46
(43%) out of 107 HBsAg postitive women. The other 61 subjects had no
recognizable risk factors. The screening of pregnant women for HBsAg only
on the basis of the CDC recommended history guidelines, would have left 57%
of our HBsAg positive mothers undetected and therefore their children
unvaccinated against hepatitis B infection. Our results confirmed the need
and value of the new CDC recommendations about routine prenatal screening
of all pregnant women for HBsAg until hepatitis B vaccine is included in
the scheme of compulsory vaccination of all newborns.
Keywords: hepatitis B,risk factors,vertical transmission,prenatal screening
- Type of paper
: Paper in proceedings
Title: Routine screening for hepatitis B in an obstetric
population
- Authors:
- Capar, Marijan (110263)
- Kosić-Andrašević, Viktorija (85181)
- Popić, Goran (162581)
- Raguž, Ljubica
- Mahulja-Stamenković, Vesna
- Žužek, Adele (188646)
- Milevoj-Ražem, Mirna
- Ljutić, Slavica
- Dujmović, Antonija
- Editors
- Peršić, Lino (85361)
Proceedings title: Dani primarne zdravstvene zaštite Labin 1993.
Language: hrvatski
Place: Labin
Year: 1993
Pages: from 133 to 137
Meeting: Dani primarne zdravstvene zaštite, Labin 1993.
Held: from 11/04/93 to 11/05/93
Summary: During 1991 and 1992 all pregnant women were sistematically
screened for hepatitis B infection in the district of Istria and Rijeka.
Among 10627 pregnant women, 107 (1%) hepatitis B surface antigen (HBsAg)
positive were registered. Checking for reliability for historic risk
factors recommended by Centers for diseases control (CDC) USA, they were
found in 46 out of 107 (43%) pregnant women. If HBsAg positive pregnant
women were screened following only the CDC recommendations, more than 50%
of them would have not been discovered, and their children would have not
been vaccinated. Our data support the recommendation for routine HBsAg
testing of all women during their pregnancy.
Keywords: hepatitis B,prenatal screening,risk factors
- Type of paper
: Paper in proceedings
Title: Results of the three year long (1991-1993) screening of
all pregnant women for hepatitis B surface antigen (HBsAg) in the counties
of Istria and Primorje-Gorski Kotar
- Authors:
- Capar, Marijan (110263)
- Kosić-Andrašević, Viktorija (85181)
- Popić, Goran (162581)
- Raguž, Ljubica
- Mahulja-Stamenković, Vesna
- Žužek, Adele (188646)
- Milevoj-Ražem, Mirna
- Ljutić, Slavica
- Editors
- Peršić, Lino (85361)
Proceedings title: Dani primarne zdravstvene zaštite Labin 1994.
Language: hrvatski
Place: Labin
Year: 1994
ISBN/ISSN: 953-96258-0-7
Pages: from 177 to 183
Meeting: Dani primarne zdravstvene zaštite, Labin 1993.
Held: from 11/03/94 to 11/04/94
Summary: During a 3-year long prospective study between January 1,
1991 and December 31, 1993 all pregnat women were screened for hepatitis B
surface antigen (HBsAg) in the counties of Istria and Primorje-Gorski
Kotar. Among 15558 women 134 (0.86%) were HBsAg positive. In 1991 out of
5396 tested pregnant women (0.9%) were HBsAg positive, in 1992 out of 5231,
57 (1.1%) were HBsAg positive and in 1993 out of 4931 tested pregnant women
27 (0.55%) were HBsAg positive. Newborns of HBsAg positive mothers were
passively and actively vaccinated in the maternity ward. All but three
newborns (from 134 HBsAg positive mothers) received an appropriate dose of
hepatitis B immunoglobuline (HBIG) and all 134 received 20 Šg recombinant
hepatitis virus (rHBV) vaccine. 51.2% of the newborns received HBIG 12
hours after delivery and 93.9% within 48 hours. Low percentage of the
historic risk factors for hepatitis B infection among our HBsAg positive
pregnant women confirms the need for screening of all pregnant women for
HBsAg until the vaccination (hepatitis B vaccine) of all newborns should
become a part of the standard battery of pediatric immunisations. Yearly
prevalence of 0.55% to 1.1% HBsAg positive pregnant women in investigated
counties corresponds positively to the also actual "cost-effectiveness"
question of routine screening of all pregnant women and vaccination of the
newborns of HBsAg positive mothers.
Keywords: hepatitis B,prenatal screening,newborn,passive and active immunisation
- Type of paper
: M.A.
Title: Goran Popić: Prevalence and importance of hepatitis B
virus carriers in the population of pregnant women
- Authors:
- Capar, Marijan (110263)
- Capar, Marijan (110263)
- Kosić-Andrašević, Viktorija (85181)
- Ljutić, Slavica
- Mahulja-Stamenković, Vesna
- Milevoj-Ražem, Mirna
- Popić, Goran (162581)
- Popić, Goran (162581)
- Žužek, Adele (188646)
Faculty: Medicinski fakultet Sveučilište u Rijeci
Date of defense: 12/05/95
Language: hrvatski
Number of pages: 52
Summary: A comprehensive programme was conducted to reduce the
incidence of hepatitis B viirus infection and its seqel in infants born of
hepatitis B surface antigen-positive (HBsAg) mothers. In the prospective
study during the period between 1 January 1991 and 30 September 1992, all
pregnant women were screened for HBsAg in the counties Primorje-Gorski
kotar and Istra, Croatia. Durimg the observed period 9203 pregnant women
gave birth to 9286 newborns. There were 94 HBsAg-positive cases (1.02%)
among mothers and they gave birth to 95 newborns. All newborns of
HBsAg-positive mothers received passive and active immunoprophylaxis in the
maternity ward. Interviewing the HBsAg-positive mothers, the physicians
obtained information regarding the presence of any of the Centers for
Disease Control risk factors for hepatitis B virus carrier state. Historic
risk factors were identified in 35 (37.23%) HBsAg -positive pregnant women.
That confirms the need for screening of all pregnant women for HBsAg until
universal hepatitis B immunisation of infants would be accepted.
Keywords: hepatitis B,risk factors,prenatal screening
- Type of paper
: Mentorship
Title: Prevalence and importance of hepatitis B virus carries in
the population of pregnant women
- Authors:
- Capar, Marijan (110263)
- Kosić-Andrašević, Viktorija (85181)
- Raguž, Ljubica
- Mahulja-Stamenković, Vesna
- Žužek, Adele (188646)
- Dujmović, Antonija
- Milevoj-Ražem, Mirna
- Ljutić, Slavica
- Popić, Goran (162581)
Faculty: Medicinski fakultet Sveučilište u Rijeci
Mentor: CAPAR MARIJAN
Date of defense: 12/05/95
Number of pages: 52
Author: Popić dr.med. Goran
Degree level: M.A.
