SVIBOR - Project code: 3-01-397

MINISTRY OF SCIENCE AND TECHNOLOGY

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Project code: 3-01-397

ACUTE RESPIRATORY INFECTIONS - DIAGNOSIS AND THERAPY

Main researcher: PETRIČEVIĆ, IVAN (36772)

Assistants

KUZMAN, ILIJA (142373)

Type of research: applied
Duration from: 01/01/91. to 12/31/94.

Papers on project (total): 22
Papers on project quoted in Current Contents: 4

Institution name: Medicinski fakultet, Zagreb (108)
Department/Institute: Department of Infectology
Address: Mirogojska 8.
City: 10000 - Zagreb, Croatia

Communication: Phone: 385 (0)1 4557-222; Fax: 385 (0)1 425-907

Summary: A total number of 4000 patients older than 6 years of age with the most frequent diagnosis of acute respiratory catarrh (2/3) and of pneumonia (1/3) were observed and treated during the period from 1991 to 1994. The intention was to make the clinical diagnosis based on the laboratory methods which are considered to be the most important for making diagnosis and for treatment. In patients with respiratory catarrh (in 2/3-3/4 of them) the proved agent was some of respiratory viruses (adeno, parainfluenza, RS, enterovirus) and in patients with pneumonia the causative agent was proved in 47% of them (Mycoplasma pneumoniae 15.6%, Chlamidia psittaci 11.7% Streptococcus pneumoniae 9.6%, Coxiella burnetti 5.6%). The incidence of atypical (nonbacterial) pneumonias was 2.3 times higher than the incidence of typical (bacterial) pneumonias. On the basis of some clinical parameters (cough, catarrh of respiratory tract, pain in the chest), on leukocyte count in the peripheral blood, and on the basis of C reactive proteins (CRP) values we could classify 90% of pneumonias as bacterial and nonbacterial ones respectively. This is important for making the choice of antibiotic before the causative agent is proved or (even more frequently) when the etiologic agent is not possible to be proved (about 1/2 of treated patients with pneumonia).

Keywords: ARI, microbial agents, diagnostic methods, antimicrobial therapy.

Research goals: The goal of observation was to determine the clinical and laboratory parameters which could reveal the nature of the disease specially when the causative agent was not proved.

COOPERATION - PROJECTS

Name of project: 0 0
Name of institution: 0

COOPERATION - INSTITUTIONS

Name of institution: Klinika za infektivne bolesti "Dr Fran Mihaljević"Zagreb
Type of institution: International organization
City: 10000 - Zagreb, Croatia

Other information about the project.


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Last update: 10/12/95
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