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Published papers on project 3-01-492


Quoted papers: 2
Other papers: 18
Total: 20


  1. Type of paper: Paper in journal

    Title: The QT interval in Q wave and non-Q wave acute myocardial infarction

    Authors:
    Mavrić, Žarko (142340)
    Zaputović, Luka (133542)
    Matana, Ante (69363)
    Plazonić, Željko
    Journal: Croatian Medical Journal
    Number: 4
    ISSN: 0353-9504
    Volume: 34
    Year: 1993
    Pages: from 314 to 318
    Number of references: 20
    Language: engleski
    Summary: The aim of the study was to analyze the QT interval in Q wave andnon-Q wave acute myocardial infarction (AMI). A total of 605patients with first AMI was divided into 2 groups: patients withQ wave AMI (QAMI, N=565); patients with non-Q AMI (NQAMI, N=40).In the NQAMI compared to the QAMI group the QTc (QT correctedaccording to Bazett's formula) was longer in the acute stage ofAMI (0.478 vs 0.447 sec, p<0.001), but not during the 3. week ofillness. Except for larger enzymatically estimated AMI size inthe QAMI group, no differences between groups regarding othervariables were found.
    Keywords: myocardial infarction, QT interval, Q wave infarction, non-Q wave infarction

  2. Type of paper: Paper in journal

    Title: Atrial fibrillation in acute inferior myocardial infarction: influence of right ventricular involvement

    Authors:
    Matana, Ante (69363)
    Mavrić, Žarko (142340)
    Zaputović, Luka (133542)
    Journal: Medicina
    Number: 1
    ISSN: 0025-7729
    Volume: 29
    Year: 1993
    Pages: from 13 to 16
    Number of references: 11
    Language: engleski
    Summary: The aim of the study was to analyze the influence of rightventricular infarction (RVI) on the incidence of atrialfibrillation (AF) in patients with inferior wall acute myocardialinfarction (AMI). A total of 225 patients with inferior AMI wasdivided into 2 groups: group I - isolated inferior AMI (N=167);group II - inferior AMI and RVI (N=58). The incidence of AF wassignificantly higher in group II than in group I (24% vs 8%).Patients with RVI and AF showed greater propensity to spontaneousconversion to sinus rhythm than did patients with isolatedinferior AMI and AF (43% vs 0).
    Keywords: acute myocardial infarction, atrial fibrillation, right ventricular infarction

  3. Type of paper: Paper in journal

    Title: Comparison of the effects of two protocols of thrombolytic therapy in patients with acute myocardial infarction

    Authors:
    Zaputović, Luka (133542)
    Mavrić, Žarko (142340)
    Marinović, Đuro
    Rupčić, Ana
    Roje, Josip
    Journal: Medicina
    Number: 1
    ISSN: 0025-7729
    Volume: 28
    Year: 1992
    Pages: from 54 to 58
    Number of references: 25
    Language: hrvatski
    Summary: By retrospective analysis the effects of two protocols ofthrombolytic therapy in patients with acute myocardial infarctionwere compared. In the first group of 54 patients reperfusion wasachieved in 76%, but with high reocclusion rate of 20%. In 190patients treated according to the second protocol, reperfusionoccurred in 73%. Although there was no difference in thereperfusion rate, a higher incidence of non-Q infarction andlower reocclusion rate (10%) were registered in the secondprotocol.
    Keywords: acute myocardial infarction, thrombolytic therapy

  4. Type of paper: Summary in proceedings

    Title: Acute myocardial infarction in the elderly: clinical course and predictors of mortality

    Authors:
    Mavrić, Žarko (142340)
    Zaputović, Luka (133542)
    Matana, Ante (69363)
    Editors
    Čikeš, Ivo
    Proceedings title: Knjiga sažetaka
    Language: hrvatski
    Place: Opatija
    Year: 1993
    Pages: from 16 to 16
    Meeting: 1. kongres Hrvatskoga kardiološkog društva
    Held: from 04/22/93 to 04/24/93
    Summary: 902 patients with acute myocardial infarction (AMI) were devidedinto age groups: <=70 years (group I, N=651) and >70 years (groupII, N=251). Group II: more women, a higher incidence of leftventricular dysfunction, arrhythmias, postinfarction angina,non-Q AMI, a higher mortality rate. Multivariate mortalitypredictors: serum lactate (p<0.001), bundle branch block(p<0.01), serum urea (p<0.01), previous AMI (p<0.01),postinfarction angina (p<0.05) in group I, and serum lactate(p<0.001), bundle branch block (p<0.001), maximal serum LDH(p<0.01) in group II.
    Keywords: acute myocardial infarction, elderly, old age, prognosis

  5. Type of paper: Summary in proceedings

    Title: The clinical importance of the right ventricular involvement in patients with acute inferior wall myocardial infarction

    Authors:
    Bradić, Nikola
    Štimac, Davor
    Zaputović, Luka (133542)
    Mavrić, Žarko (142340)
    Editors
    Čikeš, Ivo
    Proceedings title: Knjiga sažetaka
    Language: hrvatski
    Place: Opatija
    Year: 1993
    Pages: from 28 to 28
    Meeting: 1. kongres Hrvatskoga kardiološkog društva
    Held: from 04/22/93 to 04/24/93
    Summary: Patients with isolated inferior wall acute myocardial infarction(group I, N=500) and patients with right ventricular infarction(group II, N=123) were analyzed. Group II evidenced higherincidence of hypotension (21 vs 3%), systemic venous stasis (24vs 4%), pulmonary stasis (34 vs 24%), atrial fibrillation (27 vs16%), AV conduction disturbances (20 vs 7%), cardiogenic shock(15 vs 3%), higher mortality rate (15 vs 7%) and serum CK (1315vs 1125 IJ/L). Group II patients were more often treated withplasma expanders (20 vs 2%), inotropic agents (29 vs 7%),temporary pacing (15 vs 3%).
    Keywords: acute myocardial infarction, right ventricular myocardial infarction

  6. Type of paper: Summary in proceedings

    Title: Central venous canulation guided by ultrasound - the method of choice in patients with hemorrhagic diathesis

    Authors:
    Šustić, Alan
    Mavrić, Žarko (142340)
    Editors
    Čikeš, Ivo
    Proceedings title: Knjiga sažetaka
    Language: hrvatski
    Place: Opatija
    Year: 1993
    Pages: from 175 to 175
    Meeting: 1. kongres Hrvatskoga kardiološkog društva
    Held: from 04/22/93 to 04/24/93
    Summary: The authors presented their own experience withultrasonographically guided central venous canulation of theinternal jugular vein in 23 patients. In 13 patients indicationfor this technique was a marked hemorrhagic diathesis.Considering the high rate of successful canulation (91% in thefirst attempt) with no complications, the authors believe thatan ultrasonographically guided central venous canulation is amethod of choice in patients with hemorrhagic diathesis, e.g.,after thrombolytic therapy in patients with acute myocardialinfarction.
    Keywords: central venous canulation, ultrasound, hemorrhagic diathesis, thrombolytic therapy

  7. Type of paper: Summary in proceedings

    Title: Comparative analysis of the effects of different protocols of thrombolytic therapy with streptokinase in patients with acute myocardial infarction

    Authors:
    Zaputović, Luka (133542)
    Mavrić, Žarko (142340)
    Marinović, Đuro
    Matana, Ante (69363)
    Rupčić, Ana
    Roje, Josip
    Editors
    Čikeš, Ivo
    Proceedings title: Knjiga sažetaka
    Language: hrvatski
    Place: Opatija
    Year: 1993
    Pages: from 27 to 27
    Meeting: 1. kongres Hrvatskoga kardiološkog društva
    Held: from 04/22/93 to 04/24/93
    Summary: We analyzed the effects of three protocols of thrombolytictherapy with streptokinase in patients with acute myocardialinfarction, which we have been using since 1984. 65 patients weretreated according to the first, 180 to the second, and 110 to thethird protocol. In the first group reperfusion was achieved in71%, in the second in 71%, and in the third in 72% of cases. Thereocclusion rate in the first protocol was 17%, but in the secondand the third protocol it was reduced to 6% and 5%, respectively.
    Keywords: thrombolytic therapy, streptokinase, acute myocardial infarction

  8. Type of paper: Summary in proceedings

    Title: Antecedent angina pectoris and the short-term outcome after thrombolytic therapy for acute myocardial infarction

    Authors:
    Mavrić, Žarko (142340)
    Bradić, Nikola
    Matana, Ante (69363)
    Zaputović, Luka (133542)
    Editors
    Attila, Naszlady
    Proceedings title: Cardiologia Hungarica, Suppl. 3
    Language: engleski
    Place: Budapest, Hungary
    Year: 1995
    ISBN/ISSN: 0133-5596
    Pages: from 26 to 26
    Meeting: 3rd Alpe-Adria Cardiology Meeting
    Held: from 05/17/95 to 05/20/95
    Summary: Results of previous studies have noted an association between antecedent angina pectoris (AP) and the effects of thrombolytic therapy for acute myocardial infarction (AMI). Nevertheless, the reported results are not unanimous. A total of 383 consecutive patients with AMI eligible for thrombolytic treatment were included in the study. One hundred seventy-seven (46%) patients gave history of chronic AP (>1 month) before AMI. Patients with AP had a higher incidence of previous myocardial infarction (27% vs 4%, p<0.001), and recurrent ischemia (19% vs 7%, p<0.001); the incidence of non-Q AMI was also higher, but with borderline statistical significance (14% vs 8%, p=0.05). Successful reperfusion was achieved in 66% of patients with antecedent AP, and in 69% of patients without AP (p=0.66), and the reocclusion rate was the same in both groups (7%). Multivariate analysis confirmed the independent association of antecedent AP with previous infarction (p<0.001), recurrent ischemia (p<0.001), and the incidence of non-Q AMI (p=0.034). All patients were further divided into 3 groups regarding the effects of thrombolytic therapy: successful reperfusion (group 1), no reperfusion (group 2), reperfusion followed by reocclusion (group 3), and subdivided with respect to the presence or absence of antecedent AP (groups 1a, 2a, 3a, and 1b, 2b, 3b respectively). The incidence of previous infarction was higher in all groups with antecedent AP (groups 1a, 2a, 3a). The incidence of recurrent ischemia was higher in groups 1a and 2a compared to 1b and 2b, respectively. In the group of patients with reocclusion the rate of recurrent ischemia was very high, but with no difference in regard to antecedent AP. Furthermore, patients in groups 1a and 2a more frequently presented with a non-Q AMI than patients in groups 1b and 2b. The in-hospital course of patients without reperfusion or with reocclusion was more complicated, with higher incidence of left ventricular dysfunction, rhythm disturbances, and higher mortality rate, but there were no differences regarding the presence or absence of preceding AP. It is concluded that antecedent AP is an independent predictor neither of the success of thrombolytic therapy, nor the incidence of major complications in patients receiving thrombolysis for AMI.
    Keywords: Thrombolysis, acute myocardial infarction, prognosis

  9. Type of paper: Summary in proceedings

    Title: Acute myocardial infarction following hornet sting - a case report

    Authors:
    Bradić, Nikola
    Mavrić, Žarko (142340)
    Zaputović, Luka (133542)
    Matana, Ante (69363)
    Editors
    Attila, Naszlady
    Proceedings title: Cardiologia Hungarica, Suppl. 3
    Language: engleski
    Place: Budapest, Hungary
    Year: 1995
    ISBN/ISSN: 0133-5596
    Pages: from 6 to 6
    Meeting: 3rd Alpe-Adria Cardiology Meeting
    Held: from 05/17/95 to 05/20/95
    Summary: Only few studies heave reported on cases of acute myocardial infarction (AMI) after a wasp sting, and we found only one following a hornet sting. T.S., a 52 years-old man, with antecedent untreated hypertension (blood pressure values up to 230/140 mmHg) and diabetes, but without confirmed coronary disease and without data on previous hymenoptera stings, was stung in the neck by a hornet while walking in the forest. Within the next few minutes, the patient experienced an overall weakness, dizziness, shortness of breath and retrosternal pain. After emergency assistance, the patient's condition improved, but chest pain persisted until arrival to hospital three hours later. The first in-hospital ECG showed inferior AMI and right bundle branch block. On examination no generalized allergic skin reactions were observed, except erythematous papule on the sting location. Changes in CK and LDH values were characteristic for AMI, with a peak CK value of 610 IU/L (normal < 130 IU/L) and LDH peak value of 645 IU/L (normal < 276 IU/L). Blood pressure on arrival was 130/80 mmHg, relatively low for the patient's constantly high levels. The blood count showed no significant changes. The possible mechanisms of AMI occurrence after a hornet sting may be coronary spasm or sudden fall of blood pressure caused by an allergic reaction and/or direct hemodynamic effects of venom constituents.
    Keywords: Acute myocardial infarction, hornet sting

  10. Type of paper: Summary in proceedings

    Title: Relationship between QT dispersion and incidence of serious ventricular arrhythmias in patients with acute myocardial infarction

    Authors:
    Zaputović, Luka (133542)
    Mavrić, Žarko (142340)
    Zaninović, Tea
    Matana, Ante (69363)
    Bradić, Nikola
    Editors
    Attila, Naszlady
    Proceedings title: Cardiologia Hungarica, Suppl. 3
    Language: engleski
    Place: Budapest, Hungary
    Year: 1995
    ISBN/ISSN: 0133-5596
    Pages: from 45 to 45
    Meeting: 3rd Alpe-Adria Cardiology Meeting
    Held: from 05/17/95 to 05/20/95
    Summary: There is much controversy about the influence of QT dispersion on the incidence of ventricular tachycardia or fibrillation (VT/VF) in patients with acute myocardial infarction. The QT, QTc, QRS and JT dispersion (QTd, QTcd, QRSd, JTd) between two groups of patients with acute myocardial infarction were compared: 33 patients with early VT/VF (Group 1) and 40 patients without such arrhythmias (Group 2). QTd, QTcd, QRSd and JTd were calculated from the admission and predischarge ECG, expressed as the difference between maximum and minimum QT, QTc, QRS and JT interval duration in 12 leads. The coefficient of variability for each variable was also calculated (KQTd, KQTcd, KQRSd, KJTd). Groups did not differ significantly in age, incidence of previous infarction, Killip class, electrolyte status (K, Ca, Mg), infarct location, expected and final ECG infarct size, frequency of antiarrhythmic drug administration; i.e. in variables that could influence the VT/VF occurrence. Only higher frequency of thrombolytic treatment was noticed in Group 1 (61% vs 10%, p<0.001). On admission ECG patients with VT/VF had significantly greater QTd (80+-23 vs 45+-25 ms, p=0.013), QTcd (91+-27 vs 58+-36 ms, p=0.042) and JTd (76+-22 vs 45+-19 ms, p=0.016). KQTd was also significantly higher (6.72+-1.88 vs 4.47+-2.23 %, p=0.046). Although similar differences of QTd (64+-27 vs 45+-10 ms), QTcd (75+-30 vs 48+-12 ms), JTd (61+-24 vs 45+-25 ms) and KQTd (6.04+-2.59 vs 5.50+-0.43 %) existed on predischarge ECG, these differences were not significant. The results of this study indicate that QT dispersion dynamically varies during the illness, and that measurements of QT dispersion could be helpful in predicting serious ventricular arrhythmias.
    Keywords: Ventricular tachycardia, fibrillation, acute myocardial infarction

  11. Type of paper: Summary in proceedings

    Title: Effects of preceding angina pectoris on short-term outcome of patients with acute myocardial infarction

    Authors:
    Mavrić, Žarko (142340)
    Bradić, Nikola
    Zaputović, Luka (133542)
    Matana, Ante (69363)
    Editors
    Attila, Naszlady
    Proceedings title: Cardiologia Hungarica, Suppl. 3
    Language: engleski
    Place: Budapest, Hungary
    Year: 1995
    ISBN/ISSN: 0133-5596
    Pages: from 26 to 26
    Meeting: 3rd Alpe-Adria Cardiology Meeting
    Held: from 05/17/95 to 05/20/95
    Summary: Several studies reporting on the significance and prognostic importance of antecedent angina pectoris (AP) in patients with acute myocardial infarction (AMI) gave opposing results. The aim of this study was to evaluate the influence of a history of AP on short-term outcome of patients with AMI. A total of 1370 consecutive patients admitted for AIM were studied and divided into two groups. Four hundred seventy-two patients (49%) had chronic AP (> 1 month) before AIM, and 698 patients had no history of AP. Patients with AP were older (mean age 63 +- 11 vs 61 +- 11 years, p<0.001), had a higher incidence of hypertension (60% vs 51%, p<0.001), previous myocardial infarction (37% vs 5%, p<0.001), were less likely to be smokers (29% vs 48%, p<0.001), more often had signs of left ventricular dysfunction (Killip class >1) on admission (33% vs 22%, p<0.001), and presented more frequently with non-Q AMI (12% vs 7%, p=0.002). Their in-hospital course was characterized by higher incidence of severe left ventricular dysfunction (Killip class 3 and 4, 14% vs 7%, p<0.001), and higher overall mortality rate (13% vs 8%, p=0.003). Cardiogenic shock was the cause of death in 66% of patients with AP and in 42% of patients without AP who succumbed to AMI (p=0.005). Furthermore, shock was more often a fatal complication in patients with AP than in those without AP (fatality rate of 94% vs 76%, respectively, p=0.012). The incidence of recurrent ischemia was also higher in patients with preceding AP (24% vs 11%, p<0.001). There were no significant differences between two groups of patients regarding gender, incidence of diabetes mellitus, hyperlipoproteinemia, occurrence of rhythm disturbances (atrial fibrillation, ventricular tachycardia, ventricular fibrillation, AV conduction disturbances), thrombolytic treatment, and enzymatic indices of infarct size. However, a multivariate analysis, taking into account all variables that were significant in univariate analysis, confirmed the independent association of antecedent AP only with age (p=0.009), history of smoking (p=0.021), previous myocardial infarction (p=0.005), incidence of non-Q AMI (p=0.035), and recurrent ischemia (p<0.001). It is concluded that chronic AP preceding AMI predicts recurrent ischemia and the development of non-Q AMI, but that it is not independently associated with the occurrence of in-hospital complications or mortality.
    Keywords: Acute myocardial infarction, angina pectoris, prognosis

  12. Type of paper: Ph.D.

    Title: Prognostic evaluation of patients with acute myocardial infarction
    Faculty: Medicinski fakultet Rijeka Sveučilište u Rijeci
    Author: MAVRIĆ ŽARKO
    Date of defense: 09/27/91
    Language: hrvatski
    Number of pages: 150
    Summary: A total of 920 patients with acute myocardial infarction wasdivided into 2 groups: group I - survived the hospital phase ofillness (N=660), group II - died during hospitalization (N=90).Clinical, laboratory and ECG variables were analyzed byunivariate and multivariate statistical methods. Multivariatepredictors of mortality were serum lactate, urea and LDH levels,recurrent ischemia, age >70 years, bundle branch block, sinustachycardia. Prognostic index was computed using discriminantfunction analysis, revealing a good sensitivity, specificity andpredictive value.
    Keywords: acute myocardial infarction, prognosis, prognostic index


  13. Type of paper: Ph.D.

    Title: Comparison of the effects of different protocols of thrombolytic therapy in patients with acute myocardial infarction
    Faculty: Medicinski fakultet Rijeka Sveučilište u Rijeci
    Author: ZAPUTOVIĆ LUKA
    Date of defense: 12/17/93
    Language: hrvatski
    Number of pages: 179
    Summary: The effects of three protocols of thrombolytic therapy inpatients with acute myocardial infarction were compared byretrospective analysis. In 65 patients treated with the firstprotocol reperfusion occurred in 71%, but with high reocclusionrate of 17%. Although the incidence of reperfusion in 180patients treated with the second, and 110 patients treated withthe third protocol did not differ from those obtained by thefirst protocol, the reocclusion rate fell to 6% and 5%,respectively.
    Keywords: thrombolytic therapy, streptokinase, acute myocardial infarction


  14. Type of paper: Ph.D.

    Title: Right ventricular myocardial infarction - clinical characteristics and prognostic significance
    Faculty: Medicinski fakultet Rijeka Sveučilište u Rijeci
    Author: MATANA ANTE
    Language: hrvatski
    Number of pages: 248
    Summary: This study included 630 patients with inferior/posterior left ventricular myocardial infarction admitted to the Coronary Care Unit, Department of Internal Medicine, Clinical Hospital Center Rijeka, during the period 1988-1992, and covered the time of hospitalization and the first year following infarction. Patients were divided into two groups. Group I (i.e., control group) included patients with inferior/posterior left ventricular myocardial infarction without right ventricular involvement, and group II included those with inferior/posterior left ventricular infarction with right ventricular involvement (RVI) diagnosed by ECG criteria. Of the studied population 140 (22.2%) patients had RVI. The in-hospital course of patients with RVI was characterized by more complications, therapeutic particularities and a higher mortality (complications: 69.3% of patients with vs 52.6% without RVI, p <0.001; cardiogenic shock: 10.7% with vs 2.4% without RVI, p <0.001; prolonged hypotension: 5.7% with vs 1.2% without RVI, p = 0.004; electromechanical dissociation: 7.1% with vs 2.2% without RVI, p = 0.004; Killip class II: 35.0% with vs 24.1% without RVI, p = 0.01; atrial fibrillation: 15.0% with vs 8.0% without RVI, p = 0.013; malignant ventricular arrhythmias: 10.7% with vs 5.1% without RVI, p = 0.016; III0 atrioventricular block: 22.9% with vs 6.3% without RVI, p<0.001; new bundle branch block: 6.4% with vs 1.6% without RVI, p = 0.002; in-hospital mortality rate: 12.9% with vs 5.5% without RVI, p = 0.005). The most frequent cause of death was cardiogenic shock (44.4 %) in the RVI group, and left ventricle rupture (37.0%) in the control group. Patients with cardiogenic shock in both groups had a high fatality rate, although it was lower to some extent in patients with RVI (53.3% vs 66.7%, respectively, p = 0.49). The greatest difference was observed in patients with a new bundle branch block: all died in the RVI group, and not one in the group without RVI (p <0.001). In the first post-infarction year patients that recovered from RVI had fewer difficulties (41.8% with RVI vs 62.0% without RVI, p <0.001), and they less frequently required re-hospitalzation (9.8% with vs 20.5% without RVI, p = 0.007). Post-infarction angina pectoris and its unstable form were less frequent in patients with RVI (angina in 36.9% with vs 48.3% without RVI, p = 0.025; unstable angina in 2.5% with vs 7.8% without RVI, p = 0.037). The incidence of new myocardial infarction and heart failure was not significantly different in patients with compared to those without RVI. Cardiac death occurred in 3.3% of patients with RVI and in 4.3% of patients from the control group (p = 0.62), and arrhythmias were the most frequent cause of death (75.0% of patients who died in each group). The independent risk factors for RVI occurrence in patients with inferior/posterior left ventricular infarction were female sex (p = 0.028) and the absence of pre-infarction angina pectoris (p = 0.025). The independent predictors of in-hospital mortality in group I were cardiogenic shock (p <0.001), malignant ventricular arrhythmias (p <0.001), peak serum urea value (p = 0.01) and patients age (p = 0.017). In group II the predictors were cardiogenic shock (p <0.001), new bundle branch block (p <0.001), patients age (p <0.001) and serum lactate values (p = 0.025).
    Keywords: acute myocardial infarction, right ventricle


  15. Type of paper: Mentorship

    Title: Comparison of the effects of different protocols of thrombolytic therapy in patients with acute myocardial infarction
    Faculty: Medicinski fakultet Rijeka Sveučilište u Rijeci
    Mentor: MAVRIĆ ŽARKO
    Date of defense: 12/17/93
    Number of pages: 179
    Author: Zaputović Luka
    Degree level: Ph.D.


  16. Type of paper: Mentorship

    Title: Right ventricular myocardial infarction - clinical characteristics and prognostic significance
    Faculty: Medicinski fakultet Rijeka Sveučilište u Rijeci
    Mentor: MAVRIĆ ŽARKO
    Number of pages: 248
    Author: Matana Ante
    Degree level: Ph.D.


  17. Type of paper: Mentorship

    Title: The influence of QT interval dispersion on the incidence of malignant ventricular arrhythmias in patients with acute myocardial infarction
    Faculty: Medicinski fakultet Rijeka Sveučilište u Rijeci
    Mentor: ZAPUTOVIĆ LUKA
    Author: Zaninović dr.med. Tea
    Degree level: M.A.


  18. Type of paper: Invited lecture

    Title: Electrocardiographic and enzymatic estimation of acute myocardial infarct size in the evaluation of the success of thrombolytic therapy
    Institution: 1. kongres Hrvatskoga kardiološkog društva, Opatija 1993.
    Year: 1993



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