SVIBOR - Project code: 1-07-108

MINISTRY OF SCIENCE AND TECHNOLOGY

Strossmayerov trg 4, HR - 10000 ZAGREB
tel.: +385 1 459 44 44, fax: +385 1 459 44 69
E-mail: ured@znanost.hr

SVIBOR

SVIBOR - Collecting Data on Projects in Croatia

Project code: 1-07-108


MECHANISM of REACTION of METALLOPORPHYRINS, FERROCENES and METAL CYANIDES


Main researcher: AŠPERGER, SMILJKO (994)


Assistants
Type of research: basic
Duration from: 01/01/91. to 12/31/95.
Papers on project (total): 27
Papers on project quoted in Current Contents: 3
Institution name: Hrvatska akademija znanosti i umjetnosti, Zagreb (101)
Department/Institute: Research Center
Address: Ante Kovačića 5
City: 10000 - Zagreb, Croatia
Communication
Fax: 385 (0)1-44-93-78
Phone: 385 (0)1-44-90-93
Summary: Study of mechanism of reactions of metallo-porphyrins, especially of cobalt(III)(protoporphyrin IX dimethyl ester)(L1)(L2) with amine entering ligands of various basicity and pi-bonding ebility with special emphasis on the nature of the transition states. Also the kinetic and mechanism of solvolyses of ferrocenylmethyl esters has been studied by secondary alfa-deuterium kinetic isotope effects. The possibility of contribution of tunneling to large alfa-D isotope effects has been investigated.

Keywords: cobalt-porphyrins, cobalt(III)(protoporphyrin IX dimethyl ester)diligando, ferrocenylmethyl esters-solvolyse, secondary alfa-D kinetic isotope effect

Research goals: The aim was to determine the nature of the transition states in the reactions of the metalloporphyrins with piridine and imidazole and their derivatives, because the metal-imidazolenitrogen is of great biological interest (hemoglobin, mioglobin,cytochromes, cobalamins). Also, the study of secondary alfa-D kinetic isotope effect in solvolyses of ferrocenyl-methyl esters was planned, as well as the study of tunneling contribution to the large alfa-D isotope effects.

COOPERATION - INSTITUTIONS


  1. Name of institution: Farmaceutsko-biokemijski fakultet, Sveučilište u Zagrebu
    Type of institution: University/Faculty
    Type of cooperation: Joint publishing of scientific papers
    City: 10000 - Zagreb, Croatia

  2. Name of institution: Department of Chemistry, University of Rochester, Rochester, N.Y.
    Type of institution: University/Faculty
    Type of cooperation: Occasional exchange of information
    City: Rochester, SAD
Other information about the project.
MZT Croatian language SVIBOR Alphabetic list Sorted on project code Sorted on institutions Search help
Ministry of
Science and
Technology		 Croatian
language		 Svibor
homepage		 Alphabetic
list		 Sorted on
project code		 Sorted on
institutions		 Search Help
Last update: 10/19/95
Information: svibor@znanost.hr