Title: Chemical Warfare Without Chemical Agents
Title: Imidazole oximes. Reactvators of acetylcholineserase
inhibited organophosphorus compounds
Faculty: Prirodoslovno-matematički fakultet Zagreb
Date of defense: 07/15/91
Language: hrvatski
Number of pages: 121
Summary: A series of mono and bis imidazolium compounds containing
benyil, phenil, 4-metoxyphenil and 4-fluorophnyl substituents in position 3
of imidazole ring were prepared and characterised by elemental analysis, IR
and 1H NMR spectroscopy. Compounds in which one imidazole ring was replaced
by 2- and 4-hydroksyiminomethyipyridine were synthesised too. The
inhibitory power (IC-50), persentage of reactivation after inhibition by
sarin, VX, tabun and somanhave been determined for human erytrocyte AChE.
The AM-1 semiempirical calculation was performed for three of synthesesed
compounds and optimal geometry and charge of atoms are presented.
Keywords: Acetylcholinesterase, imidazolium oximes, reactivation, chemical warfare, semiempirical calculation
Title: Quinuclidinium derivatives as reactivators of
acetylcholinesterase inhibited by organophosphorus compounds
Faculty: Prirodoslovno-matematički fakultet Zagreb
Mentor: BINENFELD ZLATKO
Date of defense: 12/12/94
Number of pages: 45
Author: Primožič dipl. inž. Ines
Degree level: D.A.
Title: Imidazole oximes. Reactivators of acetylcholinesterase
inhibited by organophosphorus compounds
Faculty: Prirodoslovno-matematički fakultet Zagreb
Mentor: BINENFELD ZLATKO
Date of defense: 07/15/91
Number of pages: 121
Author: Mesić Magistar Milan
Degree level: M.A.
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