SVIBOR - Project code: 3-01-016

MINISTRY OF SCIENCE AND TECHNOLOGY

Strossmayerov trg 4, HR - 10000 ZAGREB
tel.: +385 1 459 44 44, fax: +385 1 459 44 69
E-mail: ured@znanost.hr

SVIBOR

SVIBOR - Collecting Data on Projects in Croatia

Project code: 3-01-016


Respiratory syncytial virus infections


Main researcher: MLINARIĆ-GALINOVIĆ, GORDANA (32154)


Assistants
Type of research: applied
Duration from: 04/30/91. to 12/31/94.
Papers on project (total): 30
Papers on project quoted in Current Contents: 5
Institution name: Medicinski fakultet, Zagreb (108)
Department/Institute: Department of Microbiology and Parasitology
Address: Rockefellerova 4
City: 10000 - Zagreb, Croatia
Communication
Phone: 385 (1) 426 129
E-mail: gmlinari#andrija.snz.hr
Summary: Respiratory syncytial virus (RSV) infections are the most severerespiratory infections in infants.The virus was discovered 3oyears ago, but we still have had no available active protection nor specific therapy for this disease. RSV has two subtypes (Aand B). During the lifetime period reinfections with bothsubtypes occurre.The aims of this study are: 1. detection of RSVsubtypes causing outbreaks in winter seasons in Croatia, and 2.study of relation between severity of illness and isolated RSVsubtype.The research will last at least 3 consecutive years,which will allow us to study inpatients, aged 0 to 5 years, withthe signs of acute respiratory infections throuhgout 3 winterseasons.Etiological diagnosis will be done by the direct viralmethods i.e. isolation and rapid detection of RSV from clinical specimens.

Keywords: respiratory syncytial virus, respiratory infections, bronchiolitis, pneumonia, childhood infections, RSV subtypes, monoclonal antibodies

Research goals: The aims of this research are: 1. Detection od RSV from clinical specimens.RSV subtyping will be done using monoclonal antibodies.Our previous several years lasting study showed that onthe territory of Croatia different biological variations ofRSV strains were circulating (Pediatr pulmonol 1987, Vol.3). 2.Epidemiological picture of seasonal appearance of both RSVsubtype during at least 3 consecutive years. 3. Exploration ofrelation between the clinical syndroms and isolated RSV subtype.

COOPERATION - INSTITUTIONS


  1. Name of institution: Klinika za zarazne bolesti "Dr.F.Mihaljević"
    Type of institution: University/Faculty
    Type of cooperation: Joint project
    City: 10000 - Zagreb, Croatia

  2. Name of institution: Zavod za zaštitu majki i djece
    Type of institution: University/Faculty
    Type of cooperation: Joint project
    City: 10000 - Zagreb, Croatia

  3. Name of institution: Zavod za javno zdravstvo Republike Hrvatske
    Type of institution: State institute
    Type of cooperation: Joint project
    City: 10000 - Zagreb, Croatia
Other information about the project.
MZT Croatian language SVIBOR Alphabetic list Sorted on project code Sorted on institutions Search help
Ministry of
Science and
Technology		 Croatian
language		 Svibor
homepage		 Alphabetic
list		 Sorted on
project code		 Sorted on
institutions		 Search Help
Last update: 10/12/95
Information: svibor@znanost.hr