SVIBOR - Papers quoted in CC - project code: 3-01-168

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Papers quoted in Current Contents on project 3-01-168

Quoted papers: 11
Other papers: 49
Total: 60

Title:

Authors:: Milin-Knafel, Čedomila (70123); Radošević-Stašić, Biserka (39764); Kirigin, Mladena (71782); Barac-Latas, Vesna (142193); Hinić, Višnja (103041); Rukavina, Daniel (41705); Efendić, Suad

Journal: Bioscience Reports
Number: 1
Volume: 11
Year: 1991
Pages: from 1 to 6
Number of references: 16
Language: engleski
Summary: Effects of somatostatin (SOM) on tissue contents of proteins,total lipids and phospholipids were investigated in regeneratingand intact liver tissue of Y-59 rats. Whereas SOM inhibitedprotein accumulation in regenerating liver, the hormone evoked anincrease in total lipids, and specially in phosphatidylcholine,phosphatidylethanolamine, phosphatidylserine (PS) andphosphatidylinositol (PI). Since the same effects were not seenwhen intact liver was analyzed, it is assumed that SOM actsprimarily on tissue stimulated to rapid growth. The increase ofPS+PI fractions indicates a specific interference of SOM on themetabolism of phosphatidylinositides. Such an effect might resultfrom the interference of the hormone with the action of growthfactors that accelerate phosphadylinositol breakdown.
Keywords: Somatostatin, lipid, liver, phospholipid, partial hepatectomy, regenerating liver,

Title:

Authors:: Muhvić, Damir (151520); Radošević-Stašić, Biserka (39764); Pugel, Ester (133643); Rukavina, Daniel (41705); Sepčić, Juraj (64815); Efendić, Suad

Journal: Ann. N.Y. Acad. Sci.
Volume: 650
Year: 1992
Pages: from 170 to 179
Number of references: 28
Language: engleski
Summary: Somatostatin, SMS 201-995, given shortly after encephalitogen inthe susceptible, DA strain of rats may delay the peak ofchronic relapsing form of EAE. Prolonged treatment oradministration of SMS on the 9th day protracted thesimptomatology of EAE, indicating the interference with somepostrecovery mechanisms. Similarly. abrogation of theresistance was obtained in the AO strain of rats after treatmentwith SMS in the inductive phase of the disease.
Keywords: Somatostatin, SMS 201-995, chronic relapsing form of experimental allergic encephalomyelitis, DA and AO rats.

Title:

Authors:: Radošević-Stašić, Biserka (39764); Trobonjača, Zlatko (173625); Petković, Marija (133654); Milin-Knafel, Čedomila (70123); Ćuk, Mira (85006); Muhvić, Damir (151520); Ravlić-Gulan, Jagoda (194632); Marić, Ivana; Rukavina, Daniel (41705)

Journal: Int. Arch. Allergy Immunol.
Volume: 106
Year: 1995
Pages: from 219- to 228
Number of references: 36
Language: engleski
Summary: Since it is well known that both zinc and bacterial immunostimulants influence the function of the immune system, in the present study we investigated the immunomodulating activity of a new analog of peptidoglycan monomer (PGM),in which the basic molecule was linked to zinc (PGM-Zn). Its effects in BALB/c mice, aged 10-12 months, were compared with the effects of equimolar doses of PGM and ZnCl2. The treatment lasted 26 days (one i.p. injection every fifth day). The results showed that PGM-Zn may markedly enhance antibody production to sheep red blood cells, as well as spontaneous and Con A-induced blastogenesis. The generation of plaque forming cells in individual mouse was positively correlated with the expression of class II antigens in the liver and negatively correlated with the total quantity of hepatic proteins. PGM-Zn also induced the appearance of peritoneal macrophages, which in cocultures with syngeneic splenocytes were less able to enhance the spontaneous, and particularly the ConA-induced blastic transformation. The enhancing activities of PGM-Zn were in some respects more closely correlated with the action of PGM, whereas the induction of suppressive macrophages resembled more the activity of ZnCl2. The data emphasize that PGM-Zn may both stimulate and inhibitimmunoregulative pathways by mechanisms which are not identical to those of PGM or ZnCl2.
Keywords: aging, peptidoglycan monomer, zinc, humoral immunity, hepatic class II antigens, liver proteins and nucleic acids, facs analysis, ConA-blastogenesis, suppressive macrophages.

Title:

Authors:: Radošević-Stašić, Biserka (39764); Petković, Marija (133654); Trobonjača, Zlatko (173625); Milin-Knafel, Čedomila (70123); Verbanac, Donatella (133213); Ćuk, Mira (85006); Muhvić, Damir (151520); Ravlić-Gulan, Jagoda (194632); Rukavina, Daniel (41705)

Journal: Regional Immunology
Number: 5-6
Volume: 6
Year: 1994
Pages: from 402 to 405
Number of references: 22
Language: engleski
Summary: To establish the role of T-lymphocyte subpopulations in the processes of liver regeneration following partial hepatectomy (pHx) and vice versa, the effects of factors produced in regenerating liver on lymphatic tissue, a series of studies has been conducted. Specifically, in this work we have analyzed a) the consequences of in vivo depletion of CD4 and/or CD8+ lymphocytes on hepatic DNA,RNA and proteins;and b) the consequences of pHx on phenotypic phenotypic profile of cells in spleen of mice depleted of CD4+ and/or CD8+ T lymphocytes. The data revealed that depletion of CD8+ and depletion of both CD4 and CD8+ T lymphocytes significantly augment the content of hepatic proteins and RNA in regenerating liver. The latter treatment translocated also the peak of protein synthesis from second to first post-Hx day. On the other hand, pHx stimulated the recovery of CD4+ cells in CD4+CD8-depleted mice. The data point to the existence of hepatoregulatory lymphatic cells or cytokines andto the hepatic origin of substances that lead to the induction of lymphocytes with morphogenetic properties.
Keywords: Liver regeneration, CD4 and/or CD8 depletion of lymphocytes, hepatic DNA, RNA and proteins, morphogenetic lymphocytes.

Title:

Authors:: Milin-Knafel, Čedomila (70123); Radošević-Stašić, Biserka (39764); Verbanac, Donatella (133213); Domitrović, Robert; Petković, Marija (133654); Trobonjača, Zlatko (173625); Ravlić-Gulan, Jagoda (194632); Ćuk, Mira (85006); Varljen, Jadranka; Rukavina, Daniel (41705)

Journal: Croatica chemica acta
Number: 3
ISSN: 001--1643
Volume: 68
Year: 1995
Pages: from 559 to 567
Number of references: 25
Language: engleski
Summary: Zinc is an essential trace element for many biological functions including the processes of normal growth and functioning of the lymphatic system. In this study, we estimated the role of the thymus in liver regeneration following a 1/3 partial hepatectomy (pHx) as well as the role of zinc ions in these processes. The data have shown that fast liver growth is followed by marked hypoplasia of the thymus and a difference inthe proportion of the T-cell phenotype (increase of double negative CD4-CD8- and single positive CD4+ and CD8+ cells, and decrease of double positiveCD4/CD8+ cells), Simultaneously, a significant increase of tissue zinc concentration was recorded in liver and thymus. The most pronounced increase was recorded 24 hours (liver) and 48 hours (thymus) after pHx. These results pointed to the possibility that the accumulation of zinc in both organs might be linked to the activity of growth factors which are activated by pHx. Furthermore, it is possible that activation of zinc-dependent thymic hormones or interleukins facilitates the formation of T-lymphocytes with morphogenetic functions, whichparticipate in the control of liver regeneration.
Keywords: liver regeneration, thymus, tissue zinc concentration, phenotypic profile of lymphocytes in thymus, morphogenetic lymphocytes.

Title:

Authors:: Stuhler, A.; Barac-Latas, Vesna (142193); Lassmann, H.; Wege, H.

Journal: J. Gen. Virol.
ISSN: 0001-2875
Volume: 76
Year: 1995
Pages: from 873 to 879
Number of references: 36
Language: engleski
Summary: The neurotropic mouse hepatitis virus MHV-JHM induces central nervous system demyelination in Lewis rats that pathologically resembles CNS lesions in multiple sclerosis. The mechanisms of MHV-JHM remains unclear and several studies have implicated the role of the immune responce in this process. We have shown previously that protective immunity againts MHV-JHM-induced encephalomyelitis (EM) was induced by immunization with a vaccinia virus (VV) recombinants expressing MHV-JHM S-protein (VV-S). Here, we present evidents that the time of MHV-JHM challenge after immunization with VV-S plays a critical role in protective immunity. The induction of virus-neutralizing S-protein-specific antibodies prior to the MHV-JHM challenge modulates the disease process and a subacute EM based on persistent virus infection. Typical pathological alterations were lesions of inflammatory demyelination.In addition, the results indicate that after seroconversion, CD8+ T cells were no longer essential for virus elimination in contrast to their role in protection during acute EM.
Keywords: coronavirus-induced encephalomyelitis, immunization with spike protein S, CD8+ cells

Title:

Authors:: Barac-Latas, Vesna (142193); Wege, H.; Lassmann, H.

Journal: Regional Immunology
Number: 5-6
ISSN: -
Volume: 6
Year: 1994
Pages: from 355 to 357
Number of references: 9
Language: hrvatski
Summary: In order to examine the mechanisms by which inflammatory cells can be cleared from the brain lesions in coronavirus-induced encephalomyelitis, immunohistochemical technique and in situ tailing were performed. Degenerating cells visualized by this technique were observed throughout the disease with maximum value in the last stage of disease. On average 42% of all apoptotic cell could be identified by immunocytochemistry as T lymphocytes. Morphological features reminiscent of apoptosis were not found in macrophages. Our result suggest that, similar to autoimmune encephalomyelitis, also in coronavirus-induced encephalomyelitis apoptosis of T cells may be a major mechanism to eliminate T lymphocytes from brain inflammatory lesion.
Keywords: coronavirus-induced encephalomyelitis, apoptosis of T lymphocytes, in situ tailing.


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