SVIBOR - Project code: 3-01-197

MINISTRY OF SCIENCE AND TECHNOLOGY

Strossmayerov trg 4, HR - 10000 ZAGREB
tel.: +385 1 459 44 44, fax: +385 1 459 44 69
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Project code: 3-01-197


STORAGE OF RABBIT CORNEAL TRANSPLANTS - EYE BANK


Main researcher: HENČ-PETRINOVIĆ, LJERKA (142744)



Assistants
Type of research: applied
Duration from: 09/01/91. to 12/31/96.

Papers on project (total): 108
Papers on project quoted in Current Contents: 1
Institution name: Bolnica "Sveti duh", Zagreb (129)
Department/Institute: Department of Ophthalmology , General Hospital "Sveti Duh"
Address: Sveti Duh 64
City: 10000 - Zagreb, Croatia
Communication
Phone: 385 (0)41 576 524
Fax: 385 (041)570 245

Summary: The subject of the project is the research concerning corneal transplant storage preserving the vitality of the corneal tissue and preventing the secundary infection. Beside the laboratory work the project is also dealing with clinical aspect of corneal transplantation: selection of the patients and surgical methods, postoperative follow-up with special attention being paid to the possible immunological reaction causing complications and reject of the transplant. The results of this multidiscipline research are presented in numerous publications.

Keywords: corneal transplantation, corneal tissue storage, corneal bank

Research goals: The aim of this project is to adopt corneal heterotransplantation surgical technique and to establish the basis for the future human eye bank. It was necessary to start with the experimental part of the project consisting of the short term corneal transplant storage in rabbits using specific media. specific media. The results of the surgery were followed clinically and at the and of the experiment hystopathology was performed to test the local reaction to the heterotranplant. After the experimental phase, microbiological survey of human donor tissue was done in order to assess the optimal antibiotic administration protocol for the protection of the tissue during storage . The adequate hardwer and softwer was developed to achieve impeccable information flow to the other hospitals performing corneal transplantations as well to the other centers in Europe /Eurotranplant organisation/


COOPERATION - PROJECTS


  1. Name of project: 3-01-127 Mehanizam imunološke bolesti:Novi dijagnostički postupci i standardizacija i karakterizacija alergena
    Name of institution: Imunološki zavod
    City: 10000 - Zagreb, Croatia


COOPERATION - INSTITUTIONS


  1. Name of institution: Eye bank, Corneal service, ll Allgemeines Krankenhaus
    Type of institution: University/Faculty
    Type of cooperation: Occasional exchange of experts
    City: Beč, Austria

  2. Name of institution: Zavod za ispitivanje lijekova
    Type of institution: State institute
    Type of cooperation: Joint project
    City: 10000 - Zagreb, Croatia

  3. Name of institution: Zavod za transfuziju krvi
    Type of institution: State institute
    Type of cooperation: Systematic exchange of information
    City: 10000 - Zagreb, Croatia

  4. Name of institution: Klinika za infektivne bolesti "dr. Fran Mihaljević"
    Type of institution: University/Faculty
    Type of cooperation: Systematic exchange of information
    City: 10000 - Zagreb, Croatia

  5. Name of institution: Centar za tipizaciju tkiva, KBC Rebro
    Type of institution: University/Faculty
    Type of cooperation: Systematic exchange of information
    City: 10000 - Zagreb, Croatia


OTHER ACHIEVEMENTS


  1. Name: Formiranje humane očne banke
    Type of achievement: Instrumentation
    Authors: Ljerka Henč-Petrinović, Nikica Gabrić

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Last update: 10/19/95
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