SVIBOR - Project code: 3-01-206

MINISTRY OF SCIENCE AND TECHNOLOGY

Strossmayerov trg 4, HR - 10000 ZAGREB
tel.: +385 1 459 44 44, fax: +385 1 459 44 69
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SVIBOR

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Project code: 3-01-206


MR AND CT - COMPARATIVE ANALYSIS OF ABDOMINAL AND PELVIC TUMORS


Main researcher: MAROTTI, MILJENKO (43246)


Assistants
Type of research: applied
Duration from: 01/01/91. to 12/31/93.
Papers on project (total): 44
Papers on project quoted in Current Contents: 2
Institution name: Bolnica "Sestre milosrdnice", Zagreb (134)
Department/Institute: Department of radiology,section Computerized tomography and ultd
Address: Vinogradska 29.
City: 10000 - Zagreb, Croatia
Communication
Phone: 385 (0)41 174-666/355
Summary: Early detection and staging of expansive processes is of mayor importance in the decision of proper therapy planning. The possibility of magnetic resonance imaging and computerized tomography in the detection and staging of neoplastic desease will be evaluated. The patients with liver infiltartion, adrenal, kidney, prostate,pancreas and bladder tumors will be analysed. High CT sensitivity is based on the electronically measured difference of the normal and pathological tissue densities. Advantage of MR imaging is based on the fact that signal tissue intensities are dependent on more parameters than any other radiological technique. MR imaging demonstrate proton density, T1 and T2 relaxation times describing chemical and physical enviroment. These enables high sensitivity of the focal lesion detection of parenchymal organs. Equisite possibility of MR imaging in the vessel demonstration is due to high speed velocity of blood stream resulting in the intravscular loss of signal. The result is high contrast which enables vessel demonstration without use of contrast material. Comparative studies of CT and MR possibilities in the detection of tumor like lesions and staging are in progress in many institutions. Comparative analisies of sensitivity and specificity of both methods in the detection of focal lesions and staging will be aim of the study.

Keywords: MAGNETIC RESONANCE, COMPUTERIZED TOMOGRAPHY, TUMORS, INFLAMMATION, LIVER, KIDNEY, ADRENALS, PANCREAS, PROSTATE, BLADDER, CONTRAST MEDIA, STAGING

Research goals: There are severel goals of the study. Determination of best imaging sequence for diagnosis and staging of abdominal and pelvic pathological changes on o.2 T low-field imaging device regarding spin-echo and inversion recovary techniques. Comparison of sensitivity and specificity of CT and MRI, with idea to determine the method of choice for abdominal and pelvic pathological changes. Evaluation of paramagnetic contrast media and possibility of shortenig imaging time by its use. Evaluation of sensitivity and specificity in differential diagnosis of various abdominal and pelvic pathology using GD-DTPA. Improving sensitivity and specificity of computerized tomography with contrast media in the diagnosis of abdominal and pelvic pathology. Staging of kidney tumors and possibility of differentiation mmalignant from benign tumors. Evaluation of magnetic resonance imaging in the differentiation of afunctional from functional adrenal tumors as well malignant from benign. Evaluation of computerized tomography in the differentiation of adrenal tumors on the basis of lesion density. Education of young radiologist, residents with introduction into scientific work. Work on the master of science thesis as well on the PHD thesis.

COOPERATION - PROJECTS


  1. Name of project: MULTICENTRIC STUDY OF MUSCULOSCELETAL MRI (SOFT TISSUE TUMORS)
    Name of institution: MRI CENTER ANTWERPEN
    City: ANTWERPEN, BELGIJA

COOPERATION - INSTITUTIONS


  1. Name of institution: OPĆA BOLNICA "SVETI DUH"
    Type of institution: International organization
    City: 10000 - Zagreb, Croatia
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