SVIBOR - Project code: 3-01-409

MINISTRY OF SCIENCE AND TECHNOLOGY

Strossmayerov trg 4, HR - 10000 ZAGREB
tel.: +385 1 459 44 44, fax: +385 1 459 44 69
E-mail: ured@znanost.hr

SVIBOR

SVIBOR - Collecting Data on Projects in Croatia

Project code: 3-01-409


LYME BORRELIOSIS IN CROATIA


Main researcher: KANSKY, ALEKSEJ (93955)


Assistants
Type of research: developmental
Duration from: 01/01/95.
Papers on project (total): 11
Papers on project quoted in Current Contents: 1
Institution name: Medicinski fakultet, Zagreb (108)
Department/Institute: Department of Dermatology and Venereology of Medical School of
Address: Šalata 4
City: 10000 - Zagreb, Croatia
Communication
Phone: 385 (0)1 4552-333/175
Summary: There is a very strog and convincing evidence in the literature about the association of various dermatologic, neurologic, rheumatologic and cardiologic diseases and the Borrelia burgodrferi (Bb) as a causative agent. However, such data have been consistently reviewed for Croatia and systematic investigation has not been carried out until these days.In Serologic Laboratory of our Department, ITP and FTA tests for syphilis have been routinely performed since 1954 and 1963. As the techniques for assesment of Bb are similar to certain extent, it was decided to introduce the diagnostic procedure for Bb. The propoposed investigation is planned to be carried out in order to detect the antibodies against Bb by indirect immunofluorescence, isolate and cultivate our own Bb, highly specific for our midst, produce our own antigen and isolate Bb from ticks from various localities.Furthermore,Bb should be assessed more precisely as the causative agent of various skin and systemic disorders in humans.

Keywords: Borrelia burgdorferi, Indirect immunofluorescence tests, Cultivation, Epidemiologic data, Efficient drug treatment

Research goals: -to define the biologic characteristics of Bb in Croatia -to recognize the various clinical manifestations of Lyme-disease. Special attetntion will be given to skin manifestations of Lyme disease,as they appear to be different to certain degree, depending on the part of the world. -to assess more specific and more sensible diagnostic tests for the diagnostic of Lyme disease, -to cultivate our own Bb from the biological material, highly specific for Croatia, -to produce our own antigen -to obtain the epidemiologic data forLyme-disease in Croatia -to improve the diagnosis and treatment of Lyme disease in Croatia

COOPERATION - PROJECTS


  1. Name of project: SCIENTIFIC-TECHNOLOGICAL COOPERATION WITHIN THE WORKING GROUP "ALPS-ADRIA"
    Name of institution: Dpt. of Dermatology University of Muenchen, SR Njemacka i Institute of Higyene and Microbiology, Muenchen, SR Njemacka

COOPERATION - INSTITUTIONS


  1. Name of institution: Dpt. of Dermatology, University of Muenchen and Institute of Hygiene and Microbiology, Muenchen, SR Njemacka
    Type of institution: University/Faculty
    Type of cooperation: Joint publishing of scientific papers
    City: 8000 - Muenchen, SR Njemacka
Other information about the project.
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Last update: 04/27/96
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