SVIBOR - Project code: 3-01-434

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Project code: 3-01-434


ALLERGIC DISEASES RESEARCH IN SCHOOLCHILDREN IN A COASTAL AREA OF CROATIA


Main researcher: RESTOVIĆ-SIROTKOVIĆ, MARGARITA (135555)


Assistants
Type of research: applied
Duration from: 10/10/91. to 12/30/94.
Papers on project (total): 5
Institution name: DNZ "Dr. Petar Vitezica", Split (1039)
Department/Institute: SCHOOLCHILDREN'S HEALTH CARE DEPARTMENT; ALLERGO-PULMOLOGIC DIVISION
Address: PUT GRANIČARA 1
City: 21000 - Split, Croatia
Communication
Summary: Allergic diseases are a significant scientific problem at children morbidity. By this study we wanted to establish characteristics and incidence of allergic diseases in a coastal area of Croatia, as well as define normal values of ventilatory parameters (FVC, FEV1, FEF25-75%) in children from the age of 6 to the age of 18 years in the same coastal area. In research of allergic incidence, a 2% sample of elementary schoolchildren was taken, a total of 369 pupils between the age of 6 and 14 years (179 girls and 190 boys). On the basis of the data and statistic results obtained, we appointed the incidence of allergic diseases, in the population of school children in the town of Split, to be 10.02%. On that percentage 4.06% refers to allergic bronehitis; 3.52% to allergic phonemenon on the skin; 1.09% to allergic rinitis; 0.81% to allergic conjuctivitis; 0.27% to allergy to remedies, and 0.27% to allergy to insect prick. The most frequently present allergens are home dust, Dermatophagoides pteronyssinus, grass pollens, feathers, animal hair. The multiple linear regression equations were worked out for calculation of the referent values FVC, FEV1, FEF25-75% for the school children ranging in age from 6 to 18 years:(girls) FVC = 0.03296 x STANDING HEIGHT + 0.09170 x AGE - 3.37147 FEV1 = 0.03142 x STANDING HEIGHT + 0.08171 x AGE - 3.16798 FEF25-75% = 0.03597 x STANDING HEIGHT + 0.09582 x AGE - 3.07766 ranging in age from 6 to 18 (boys) FVC = 0.04634 x STANDING HEIGHT + 0.07952 x AGE - 5.00129 FEV1 = 0.04117 x STANDING HEIGHT + 0.07646 x AGE - 4.38161 FEF25-75% = 0.04154 x STANDING HEIGHT + 0.10655 x AGE - 3.95733 On the basis of the proper normal values of ventilatory parameters we calculated the grade of lesion of pulmonic function and we obtained 1.89% schoolchildren had ventilation obstruction and of that percentage 1.62% of healthy schoolchildren being without any sign of allergic diseases. 18.7% of schoolchildren had positive Ventolin test for ventilatory parameters; of that percentage 3.26% of pupils had allergic diseases; 7.31% has often had a cold, or in infant age had, once or twice, one of the previous mentioned allergic diseases; 8.13% had no sign of any allergic diseases.

Keywords: Children, allergic diseases, skin tests, ventilatory parameters.

Research goals: - Examination of the incidence of allergic diseases in children in a coastal area of Croatia with a view to early discovery and prevebtion of them. - Examination of the incidence and intensity of cutaneons oversensitiveness inhaleting allergens. - Comparison of intensity of skin reaction with a level specific IgE antibodies with appointing the level IgE in serum due to insight into atopic predisposition of examines, i.e. a kind of allergic reaction. - Appointing the normal values of lungs functions (FVC, FEV1, FEF25-75%) in schoolchildren ranging in age from 6 to 18 years at the same region, then on the basis of the proper normal values of ventilatory parameters calculating the grade of lesion of lungs function due to early discovery and prevention of obstruction.

COOPERATION - INSTITUTIONS


  1. Name of institution: RADIO IZOTOPNI LABORATORIJ - KLINIČKI BOLNIČKI CENTAR SPLIT SPINČIĆEVA 1
    Type of institution: International organization
    City: 21000 - Split, Croatia
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Last update: 03/17/94
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