SVIBOR - Project code: 3-01-438

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Project code: 3-01-438


BIOMEHANICAL ANALYSIS OF OSTEOGENESIS (APOPHYSIAL BONE GROWTH) IN COXARTHROSIS


Main researcher: JOVANOVIĆ, SAVO (128715)


Assistants
Type of research: basic
Duration from: 01/01/91. to 12/31/96.
Papers on project (total): 8
Papers on project quoted in Current Contents: 1
Institution name: Bolnica, Znanstvena jedinica za klinička medicinska istraživanja, Osijek (127)
Department/Institute: Department of Orthopaedics
Address: Radićeva 23. Osijek, CROATIA
City: 31000 - Osijek, Croatia
Communication
Summary: The influence of biomechanical factors on osteogenetical processes in the area of the proximal part of femur and acetabulum in coxarthrosis was analyzed in the research article. Detailed clinical, radiological, histological and histochemical research of apositional growth of the bone in width in the areas of greater smaller strain caused by arthrotical process and by verticalization of the force of weight-bearing of the hip with sidewise limping is performed. The chosen patients are analyzed scintigrafically and by axial computerized tomography. The material for laboratory examinations is obtained from operations of total hip replacement while that part of proximal femur is removed.

Keywords: diferentiation of mesodermal tissue, osteogenesis, mehanical factors, proximal part of femur

Research goals: The aim of the study is biomechanical analysis of the influence of mechanical factors on osteogenesis under influence of different quality of strain. Expirience shows that Roux's theory of the transversal growth of the bone, so-called preiostal way, is not in accordance with clinical research with respect to functional adjustment. The point of disagreement is Roux's presumption from 1895. that isolated pressure or drag strain alternatly with drag strain influence the creation of bone tissue, and strain with pressure and drag strain influences the creation of cartilage. That aproach also did not find any clinical use. This also applies for Pauwel's theory of longitudinal growth of the bone in enhondral way. The influence of mechanical factors on the growth of the bone in length was presented only for epiphisiar growth of the head of femur. A contribution in explanation of the way of differentiation of microstructure of mesodermal tissue with respect to different strains in quality on the neck and head of femur in coxarthrosis could be expected from this research.

OTHER ACHIEVEMENTS


  1. Name: Morfološka analiza promjena glave femura u bolesnika s koksartrozom Diplpmski rad, 1993, mentor: prim. dr Savo Jovanović Sveučilište u Zagrebu, Studij medicine Osijek, 52 stranice
    Type of achievement: Other
    Authors: Sanja Svalina
Other information about the project.
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