SVIBOR - Project code: 3-01-498

MINISTRY OF SCIENCE AND TECHNOLOGY

Strossmayerov trg 4, HR - 10000 ZAGREB
tel.: +385 1 459 44 44, fax: +385 1 459 44 69
E-mail: ured@znanost.hr

SVIBOR - Collecting Data on Projects in Croatia

Project code: 3-01-498

Study of uterine and ovarian perfusion in fertile and infertile women

Main researcher: KUPEŠIĆ-UREK, SANJA (66854)

Assistants

KURJAK, ASIM (24866)
STILINOVIĆ, KREŠIMIR (196702)
BABIĆ, MARIJA MAJA (900804)

Type of research: developmental
Duration from: 01/01/93. to 12/31/96.

Papers on project (total): 150
Papers on project quoted in Current Contents: 11

Institution name: Bolnica "Sveti duh", Zagreb (129)
Department/Institute: Department of Obstetrics and Gynecology
Address: Sveti Duh 64
City: 10000 - Zagreb, Croatia

Communication: Phone: 385 (0)41 579 251; Fax: 385 (0) 41 579 298

Summary: The aim of this prospective study is to establish diagnostical and interventional abilities as well as reach of Transvaginal and pulsed color Doppler (TVCD) in the management of infertile patients. Further steps include improvement of already present methods in human repoduction, increased acccuracy and simplicity of invasive procedures and diminished costs of IVF/ET.Doppler results will be compared to hormonal levels in order to establish the standards of ovarian and uterine pefusion.These data will possibly define the optimum moment for oocytae aspiration and embryo transfer. Diagnostic and therapeutic values of Doppler hysterosalpingography will be evaluated. In case of unruptured tubal pregnancy local instilation of methotrexate will be guided by TVCD.

Keywords: Transvaginal color Doppler, Infertility, Uterine perfusion, Ovarian perfusion

Research goals: The goal is to compare uterine and ovarian arterial Doppler features to hormonal levels (E2, FSH, LH, PROG) during spontaneous and stimulated ovarian cycles (different stimulation protocols). Furthermore, we will estimate the corelation between itra-ovarian Doppler paterns and maturity of the oocyte on one, and uterine perfusion and uterine receptivity on another side. Reliability of TVCD in diagnostic (HSSG) and therapeutic (local application of metothrexate in ectopic pregnancy) procedures will be estimated.

Other information about the project.


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Last update: 10/12/95
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