SVIBOR - Project code: 3-01-526

MINISTRY OF SCIENCE AND TECHNOLOGY

Strossmayerov trg 4, HR - 10000 ZAGREB
tel.: +385 1 459 44 44, fax: +385 1 459 44 69
E-mail: ured@znanost.hr

SVIBOR

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Project code: 3-01-526


MATHEMATICAL AND STATISTICAL MODELS OF HAEMATOLOGICAL DISEASES


Main researcher: PIŠL, ZORAN (82896)



Assistants
Type of research: basic
Duration from: 06/01/94.

Papers on project (total): 8
Papers on project quoted in Current Contents: 1
Institution name: Institut za medicinska istraživanja i medicinu rada, Zagreb (22)
Department/Institute: Department of biomathematics
Address: Ksaverska cesta 2, pp 291
City: 10000 - Zagreb, Croatia
Communication
Phone: 385 (0)1 214 460
Fax: 385 (0)1 274 572
E-mail: zpisl@mimi.imi.hr

Summary: We will develop and apply mathematical and statistical models for dynamics and therapy of haematological diseases. An expert system will be established by which will enable early detection and interpretation of some undesirable events occuring during therapy. A simulation model of the dynamics of haematological diseases in population will be developed.

Keywords: mathematical model, haematological diseases, bone marrow, transplantation, simulation, data base

Research goals: The scope of our research is to establish an expert system by specific mathematical and statistical methods and neural networks. This system would make it possible to predict, with acceptable degree of certainty, the outcome of therapy and in this way physicians could avoid possible complications. This expert system would be connected with the existing data base and would make an integral system in treating leukemias. By using the example of Marek's poultry disease we would examine how this model describes the development of the disease in experimental conditions. Within the framework of this project we would also develop specific statistical methods and work out computer programmes for longitudinal data analysis. General simulation model of the dynamics of infectious diseases would be modified so that it could be applied to non-infectious diseases. Epidemiological studies would determine risk factors that influence development of leukemias in specific sub-populations.


COOPERATION - PROJECTS




COOPERATION - INSTITUTIONS


  1. Name of institution: Veterinarski fakultet Sveučilišta u Zagrebu
    Type of institution: University/Faculty
    Type of cooperation: Joint project
    City: 10000 - Zagreb, Croatia

  2. Name of institution: Klinički bolnički centar Rebro
    Type of institution: University/Faculty
    Type of cooperation: Joint project
    City: 10000 - Zagreb, Croatia

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Last update: 10/06/95
Information: svibor@znanost.hr