IMMUNE RESPONSE AS A MARKER OF NEEDS ON VITAMINS IN CHICKEN
Main researcher
: ŠERMAN, VLASTA (46523) Assistants
MAS, NORA (34681)
DUMANOVSKY, FRANJO (111051)
Type of research: applied Duration from: 04/30/91. to 12/31/94. Papers on project (total): 60
Institution name: Veterinarski fakultet, Zagreb (53) Department/Institute: Department for animal nutrition Address: Heinzelova 55 City: 10000 - Zagreb, Croatia
Communication
Phone: 385 (0)290 270
Fax: 385 (0)290 111
Summary: 1. experiment The influence of
increased amount of vitamins A and E respectively in a diet of fattening
chicks to the immune response of animals and to production results was
examined during the 42 days of fattening. The immune response and the
bursa Fabritius index were better the higher were the supplements of
vitamin A and vitamin E respectively in the diet. The highest values were
obtained three weeks after the vaccination in groups fed by starter feed
containing 50,000 IU vitamin A and 120 IU vitamin E per kilogram and by
finisher feed containing 40,000 IU of vitamin A and 100 IU of vitamin E
per kilogram of feed. Increased amount of vitamins A and E in a diet did
not show any significant influence to the body weight and feed conversion
compared with the control group fed by normal starter feed (12,500 IU of
vitamin A and 30 IU of vitamin E per kilogram) and normal finisher feed
(10,000 IU of vitamin A and 25 IU of vitamin E per kilogram).After
comparison of the immune response to Newcastle disease vaccine among the
groups it was faund that the highest amount of vitamin A provoked the best
response. However, HI titers were the best only three weeks after the
vaccination. These results indicate that more vitamin A in starter feed
had benefical effecton immune response. Based on this, it is better to
reduce the amounts of vitamin A in finisher feed. The best immune response
measured by HI titres of specific antibodies had the group with the highst
amount of vitamin E. Titers in all other groups after age of 21 days
started to decrease until the 28th day. Index of bursa Fabricius measured
at age of 42 days was the highest and similar to results of control group.
2. experiment The effect of the increased amounts
of Vitamin A and E on the development of immunocompetent organs in
chickens have been investigated during a period of 42 days. The results
indicate that usage of Vitamin A in the quantity three times larger than
recommended in pratice (starter 12500 IU and finisher 10000 IU per
kilogram) had the most favorable effects on the development of bursa
Fabricius and on the absolute and relative mass of spleen. In the trial
with Vitamin E the biggest absolute and relative mass of spleen was
achieved with the quantity of Vitamin E three times larger than the usual
one. The best effect on the bursa Fabricius had the usual 30 IU (starter)
and 25 IU (finisher) Vitamin E. Larger quantities of Vitamin E had
deppresive effects on the development of this organ.Neither one of these
two vitamins had significant effects on the immune response to the
vaccinal virus of Newcastle Disease. 3. experiment
The influence of increased amount of Vitamin C in a diet of fattening
chicks to production results and to the immune response to Newcastle
Disease vaccine was investigated. The added of Vitamin C (2 g/l and 4 g/l
water) did not have any significant effect on the body weight, but feed
conversion was better compared to a control group. In the stress condition
Vitamin C had the most favorable effect on the development of body mass
than on the immune responce after the vaccination.
Keywords: vitamin A, vitamin E, vitamin C, chicks, nutrition, body mass gain, conversion, immune response, HI titres, bursa Fabricius, Newcastle disease vaccine
Research goals: The goal of the research was to estimate vitamins
needs in poultry with respect to the development of immune system and its
functionality. If these criteria prove themselves as the suitable base for
estimation of needs in case of vitamins A and E, the research would be
extended to water soluble vitamins (B complex and C) in the future. The
results of the research are expected to improve specific health protection
in poultry production. Other information about the project.