- Type of paper
: Paper in journal
Title: Effect of radioactive isotope P-32 upon blood plasma
protein concentration and its electrophoretical fractions in
chickens
- Authors:
- Kraljević, Petar (23266)
- Križanović, Dubravka (23696)
- Emanović, Dubravko
Journal: Veterinarski arhiv
Number: 5
ISSN: 0372-5480
Volume: 61
Year: 1991
Pages: from 313 to 319
Number of references: 11
Language: hrvatski
Summary: An attempt was made to investigate whether the liver
functionaldamage caused by ionizing radiation results in a decrease of
theprotein synthesis and whether blood plasma proteins, like theenzyme
activity, can serve for the early diagnosis of the liverdamage coused by
ionizing radiation. Among determined parametersonly alpha- and
gamma-globulin statistically significantlychanged on the 7th day of the
experiment; alpha-globulin wereincreased (P<0.05) and gamma-globulins
decreased (P<0.01). Thesedata suggest that serum proteins are less
sensitive parameters offunctional liver damage in chickens caused by
ionizing radiationthan the enzyme activity.
Keywords: radioactive isotope P-32, proteins, protein fractions, protein subfractions, blood plasma, chickens.
- Type of paper
: Paper in journal
Title: The changes of serum enzyme activity as an indicator of
radiation injuries in chickens.
- Authors:
- Kraljević, Petar (23266)
- Emanović, Dubravko
Journal: Periodicum biologorum
Number: 2
ISSN: 0031-5362
Volume: 95
Year: 1993
Pages: from 249 to 253
Number of references: 33
Language: engleski
Summary: An attempt was made to evaluate whether investigation of
theactivity of several enzymes (enzymatic profile) in blood plasmacan help
in the diagnosis of organic or functional liver damagecaused by ionizing
radiation in the chicken. Throughout theinvestigation there was a decreased
tendency of all enzymeactivity levels, but statistically significant
decreases wererecorded as follows: on 3th day of the experiment -
alanineaminotransferase (ALT) and leucine aminopeptidase, on 5th day -ALT
activity, on the 7th day - ALT, lactate dehydrogenase,
andalpha-hydroxy-butirate dehydrogenase actibity, and on the 10thday - ALT
and gamma-glutamyl transpeptidase activity.
Keywords: radioactive phosphorus P-32, aspartate aminotransferase, alanine aminotransferaze, lactate dehydrogenase, alpha-hydroxy-butyrate dehydrogenase, blood plasma, chickens.
- Type of paper
: Paper in journal
Title: Effect of combined injures on some haematological
parameters in the dogs blood
- Authors:
- Šimpraga, Miljenko (104775)
- Kraljević, Petar (23266)
- Bedrica, Ljiljana (117331)
- Božičković, Predrag (4991)
- Capak, Darko (116995)
Journal: Veterinarski arhiv
Number: 6
ISSN: 0372-5480
Volume: 61
Year: 1991
Pages: from 355 to 364
Number of references: 12
Language: hrvatski
Summary: The attempt was made to investigate the red blood cell
count, theerythrocyte sedimentation rate, the hematocrit and
hemoglobinconcentration; MCV, MCH and MCHC in the blood oh dogs
withcombined injuries (bone fracture + gamma-irradiation). Inaddition, the
iron and copper concentrations in the bloodplasma were determined. The
results obtained have shown that thecombined injury as this one described,
can probably cause changesin some investigated parameters.
Keywords: combined injury, irradiation, bone fracture, erythrocyte, hematocrit, hemoglobin, sedimentation rate, iron, copper, peripheral blood, dog
- Type of paper
: Paper in journal
Title: Effect of combined injury on dog,s white blood cells
- Authors:
- Šimpraga, Miljenko (104775)
- Bedrica, Ljiljana (117331)
- Miljanić, Saveta (31965)
- Capak, Darko (116995)
- Kraljević, Petar (23266)
Journal: Veterinarski arhiv
Number: 6
ISSN: 0372-5480
Volume: 63
Year: 1993
Pages: from 297 to 305
Number of references: 23
Language: hrvatski
Summary: An attempt was made to investigate the effect of a bone
fracture treated by a stabilized ostesynthesis and the bilateral
irradiation of the whole body by a dose of 2 Gy (Co-60) on the white blood
cells in dogs. The results obtained have shown that in dogs a combined
injury of such type and intensity will not cause enhanced effects, For this
reason, detected changes in white blood cells reflect only the effect of
the irradiation dose absorbed by the animals.
Keywords: combined injury, irradiation, bone fracture, white blood cells, dog
- Type of paper
: Paper in proceedings
Title: Blood picture in chickens after aplication of lethal dose
of P-32.
- Authors:
- Šimpraga, Miljenko (104775)
- Kraljević, Petar (23266)
- Vekić, Branko (51732)
- Kecerin, Branka
Proceedings title: Zbornik radova
Language: hrvatski
Place: Neum, Bosna i Hercegovina
Year: 1991
Pages: from 192 to 195
Meeting: XVI jugoslovenski simpozijum za zaštitu od zračenja
Held: from 05/28/91 to 05/31/91
Summary: The attempt was made to investigate the effects of lethal
dose ofP-32 (333 MBq/kg of body weight) on the red blood cell
count,hemoglobin concentration and hematocrit in the chickens blood.The
obtained results have shown significant effect of P-32 onerytrocytes on the
5th day and on hemoglobin concentration andhematocrit on the 7th day after
injection of P-32.
Keywords: radioactive phosphorus P-32, erytrocytes, hemoglobin, hematocrit, blodd, chicken.
- Type of paper
: Paper in proceedings
Title: Clinical and pathomorphological changes of chickens
contaminated by lethal dose of P-32.
- Authors:
- Šimpraga, Miljenko (104775)
- Tišljar, Marina (130726)
- Stojević, Zvonko
- Grabarević, Željko (14604)
- Kraljević, Petar (23266)
- Editors
- Franić, Zdenko
- Kubelka, Dragan
Proceedings title: Zbornik radova prvog simpozija hrvatskog društva za zaštitu od zračenja
Language: hrvatski
Place: Zagreb
Year: 1992
Pages: from 101 to 106
Meeting: Prvi simpozij hrvatskog društva za zaštitu od zračenja
Held: from 11/24/92 to 11/26/92
Summary: The attempt was made to investigate the clinical
andpathomorphological effects of lethal amount of radioactivephosphorus
P-32 in chickens after their parentheraladministration. Clinical
observations on the experimental groupshowed in all birds the symptoms of
the radiation disease. Grossepathoanatomical findings in the experimental
group includedsevere anemia, dispersal punctate hemorrhages beneth
serosalsurfaces of the hart, intestine and lungs. The most
severehistopathological lesions were found on the small arteries
andlymphopoetic tissue.
Keywords: radioactove phosphorus P-32, clinical effects, pathoanatomical effects, histopathological effects, chickens.
- Type of paper
: Paper in proceedings
Title: Investigation of some Biochemical parameters in chicken
blood plasma after internal contamination by lethal dose of P-32.
- Authors:
- Kraljević, Petar (23266)
- Stojević, Zvonko
- Šimpraga, Miljenko (104775)
- Emanović, Dubravko
- Milinković-Tur, Suzana
- Mitin, Vladimir
- Editors
- Franić, Zdenko
- Kubelka, Dragan
Proceedings title: Zbornik radova prvog simpozija hrvatskog društva za zaštitu od zračenja
Language: hrvatski
Place: Zagreb
Year: 1992
Pages: from 107 to 111
Meeting: Prvi simpozij hrvatskog društva za zaštitu od zračenja
Held: from 11/24/92 to 11/26/92
Summary: Fifty day old hybrid of chickens of havy Jata breeds of
bothsexes, were treated by P-32 administreted i.m. as sodiumorthophosphste
in a single dose of 333 MBq per kilogram of bodyweight. The obtained
resultates indicate that all threeinvestigated parameters are slight
sensitive on ionizingradiation, and, therefore, they can not serve as
indicators offunctional injuries of liver in chickens caused by
ionizingradiation.
Keywords: radioactive phosphorus P-32, cholesterol, total lipids, cholinesterase, blood plasma, liver, chickens
- Type of paper
: Paper in proceedings
Title: Aminotransferasesactivity in blood plasma of dogs with
combined radiation injury.
- Authors:
- Kraljević, Petar (23266)
- Šimpraga, Miljenko (104775)
- Capak, Darko (116995)
- Miljanić, Saveta (31965)
Proceedings title: Zbornik radova XVI. jugoslovenskog simpozija za zaštitu od zračenja
Language: hrvatski
Place: Neum, Bosna i Hercegovina
Year: 1991
Pages: from 162 to 164
Meeting: XVI jugoslovenski simpozijum za zaštitu od zračenja
Held: from 05/28/91 to 05/31/91
Summary: Influence of combined injury (bone fracture + 2
Gygamma-irradiation) upon aspartate aminotransferase (AST) andalanine
aminotransferase (ALT) activity in blood plasma of dogwas investigated. The
obtained results showed that only ALTactivity changed in the blood plasma
while the AST activityremaind unchanged.
Keywords: combined injury, bone fracture, irradiation, aspartate aminotransferase, alanin aminotransferase, blood plasma, dog.
- Type of paper
: Paper in proceedings
Title: Pathomorphological changes in dogs with combined injury.
- Authors:
- Grabarević, Željko (14604)
- Šimpraga, Miljenko (104775)
- Kraljević, Petar (23266)
- Capak, Darko (116995)
- Gomerčić, Hrvoje
- Vuković, Živana
- Editors
- Franić, Zdenko
- Kubelka, Dragan
Proceedings title: Zbornik radova prvog simpozija hrvatskog društva za zaštitu od zračenja
Language: hrvatski
Place: Zagreb
Year: 1992
Pages: from 112 to 117
Meeting: Prvi simpozij hrvatskog društva za zaštitu od zračenja
Held: from 11/24/92 to 11/26/92
Summary: An attempt has been made to investigate the
pathomorphologicalchanges in dogs with combined injury (bone fracture + 2
Gygamma-irradiation). Necropsy examination of the selected organsshowed
changes in experimental - irradiated group.Pathohistological findings in
the experimental group of animalswere divergent compared to the control.
All lesions which wereseen microscopically in the liver, kidney, adren,
heart, lymphnodes and spleen corresponded to the so called "delayed type
ofinjury" which is mainly the consequence of the fine vascularelesions with
progressive sclerosis and fibrosis of the involvedtissue.
Keywords: combined injury, bone fracture, irradiation, patomorphological changes, dog.
- Type of paper
: Paper in proceedings
Title: Effects of lethal amounts of P-32 upon aminotranferases
activity in chickens blood plasma
- Authors:
- Kraljević, Petar (23266)
- Šimpraga, Miljenko (104775)
- Emanović, Dubravko
- Editors
- Franić, Zdenko
- Kubelka, Dragan
Proceedings title: Zbornik radova drugog simpozija hrvatskog društva za zaštitu od zračenja
Language: hrvatski
Place: Zagreb
Year: 1994
ISBN/ISSN: 53-96133-0-2
Pages: from 241 to 244
Meeting: Drugi simpozij hrvatskog društva za zaštitu od zračenja
Held: from 11/23/94 to 11/25/95
Summary: The attempt was made to investigate the effects of lethal
amount of P-32 (333 Mbq/kg of body weight) upon aminotransferases (ALT,
AST) activity in chickens blood plasma. The results obtained have shown
that ALT activity was increased during the first five days of the
experiment, and on 7th and 10th day it was decreased; statistically
significant difference was recorded on the 7th day only. AST activizy was
increased on 3rd and 5th day and it was decreased on the 7th and 10th day
of the experiment.
Keywords: chickens, contamination, P-32, aspartat-aminotransferases, alanin-aminotrasferases,
Other:
- Type of paper
: Paper in proceedings
Title: Effect of P-32 lethal dose on whitw blood cells in
chickens
- Authors:
- Šimpraga, Miljenko (104775)
- Kraljević, Petar (23266)
- Editors
- Franić, Zdenko
- Kubelka, Dragan
Proceedings title: Zbornik radova drugog simpoyija hrvatskog društva za zaštitu od zračenja
Language: hrvatski
Place: Zagreb
Year: 1994
ISBN/ISSN: 953-96133-0-2
Pages: from 271 to 276
Meeting: Drugi simpozij hrvatskog društva za zaštitu od zračenja
Held: from 11/23/94 to 11/25/95
Summary: The attempt was made to investigate the effects of lethal
dose of beta bone-seeking radionuclides (radioactive phosphorus P-32) on
white blood cells in broilers chickens. Obtained results have shown the
leukopenia at the 1st day after injection of P-32 as a consequences of
lymphocyte number diminution which was accompaniied with eosinopenia from
day 3, and heterophilopenia from day 5 up to the end of the experiment.
Keywords: chickens, contamination, P-32, leukocyte, lymphocyte, eosinophils, heterophils,
- Type of paper
: Summary in proceedings
Title: Kraljević, P., Emanović, D., Šimpraga, M. Effect of lethal
dose of P-32 upon lactate and alpha-hydroxy-butyrate dehydrogenase
activity in chicken blood plasma.
Proceedings title: Abstracts
Language: engleski
Place: Erfurt, Germany
Year: 1992
Pages: from 186 to 0
Meeting: 24th Annual Meeting of the European Society for Radiation Biology
Held: from 10/04/92 to 10/08/92
Summary: An attempt has been made to investigate the effect of 333
MBqper kilogram of body weight upon lactate andalpha-hydroxy-butyrate
dehydrogenase (LDH, HBDH) activity inblood plasma of fifty day old hybrid
chickens of heavy "Jata"breeds . The results obtained have shown that LDH
activity wasslightly increased during the first three days of the
experiment,and on the 7th and 10th day it was decreased. HBDH activity
wasincreased during the first five days of experiment and it wasdecreased
on the 7th and 10th day of experiment.
Keywords: radioactive phosphorus P-32, lactate dehydrogenase, alpha-hydroxy-butirate dehydrogenase, blood plasma, chickens.
- Type of paper
: Summary in proceedings
Title: Kraljević, P., Emanović, D., Šimpraga, M. Effect of lethal
dose of P-32 upon leucine aminopeptidase and
gamma-glutamyl-transpeptidase activity in chicken blood plasma.
Proceedings title: Abstracts
Language: engleski
Place: Stockholm, Švedska
Year: 1993
Pages: from 707 to 0
Meeting: 25th Annual Meeting of the European Society for Radiation Biology
Held: from 06/10/93 to 06/14/93
Summary: An attempt has been made to investigate the effect of 333
MBq perkilogram of body weight of radioactive phosphorus P-32administred
i.m. in a single dose, upon leucin aminopeptidase(LAP) i
gamma-glutamyl-transpeptidase activity in blood plasma offifty day old
hybrid chickens of haevy "Jata" breeds. The resultsobtained have shown that
LAP activity was decreased during allexperimental period, except on day 5
when it was slightlyincreased. GGT activity was practically unchanged up to
5, whenit was also slighty increased, and it was decreased on the 7thand
10th day of experiment.
Keywords: radioactive phosphorus P-32, leucine aminopeptidase, gamma-glutamyl-transpeptidase, blood plasma, chickens.
- Type of paper
: Summary in proceedings
Title: Kraljević, P. Šimpraga, M., Emanović, D.
Gamma-glutamyl-transpeptidase activity in chicken blood plasma after
internal contamination by various doses of P-32
Proceedings title: Veterinarska znanost i struka
Language: hrvatski
Place: Zagreb
Year: 1993
Pages: from 12 to 0
Meeting: Znanstveno-stručni sastanak
Held: from 06/24/93 to 06/25/93
Summary: An attempt has been made to investigate the effect of
variousdoses of P-32 upon gamma-glutamil-transpeptidase (GGT) activityin
chichen blood plasma. The results obtained have shown that GGTactivity was
changed during experimental period, but as changesof GGT activity apears
after changes of some other parameters inblood plasma, GGT activity is not
parameter for early discoveryof biochemical damage in contaminated chicken.
Keywords: radioactive phosphorus P-32, gamma-glutamyl-transpeptidase, blood plasma, chickens.
- Type of paper
: Summary in proceedings
Title: Šimpraga, M., Bedrica, Lj., Miljanić, S., Capak, D.,
Kraljević, D. Total leukocyte and lymphocyte count in blood of dogs with
combined injuries
- Authors:
- Bedrica, Ljiljana (117331)
- Capak, Darko (116995)
- Miljanić, Saveta (31965)
Proceedings title: Vetrinarska znanost i struka
Language: hrvatski
Place: Zagreb
Year: 1993
Pages: from 95 to 0
Meeting: Znanstveno-stručni sastanak
Held: from 06/24/93 to 06/25/93
Summary: An attempt has been made to investigate the effect of
combinedinjury (bone fracture + 2 Gy gamma-irradiation) on totalleukocytes
nad lymphocytes count in dogs blood. The resultsobtained have shown that
after combined injury like this thechanges in peripheral blood would be
result only from the effectsof irradiation dose but not from the bone
fracture.
Keywords: combined injuries, gamma-irradiation, bone fracture, osteosinthesis, leukocytes, lymphocytes, peripheral blood, dog.
- Type of paper
: Summary in proceedings
Title: Kraljević, P., Šimpraga, M., Emanović, D. Effects of P-32
upon aminotransferases activity in chikens
Proceedings title: Abstracts of the IUPS regional meeting in Prague 1991
Language: engleski
Place: Prag, Poljska
Year: 1991
Pages: from 104 to 0
Meeting: Regional meeting of the International Union of Physiological Science
Held: from 06/30/91 to 07/05/91
Summary: An attempt has been made to investigate whether
aspartateaminotransferase (AST) and alanine aminotransferase (ALT)activity
change in the blood plasma of chickens after internalradioactive
contamination. The results obtained have shown thatALT activity was
increased during the first five days ofexperiment, and on the 7th and 10th
day was decreased;statistically significant difference was recorded on the
5th dayonly. AST activity was increased on the 3rd and 5th day and itwas
decreased on 7th and 10th day of experiment.
Keywords: radioactive phosphorus P-32, aspartate aminotransferase, alanin aminotransferase, blood plasma, chickens.
- Type of paper
: Ph.D.
Title: Effect of radioactive phosphorus 32P upon some
haematological and biochemical parameters in chicken blood.
Faculty: Veterinarski fakultet Zagreb
Date of defense: 06/18/93
Language: hrvatski
Number of pages: 114
Summary: The experiments were carried out on 50 day hybrid chickens
of thehaevy "Jata" breed of both sexes after internal contaminationwith 333
MBq/kg body weight of 32P. Obtained results have shownas follows: 1) an
anemia from 5th day after contamination; 2) theleukopenia after 1st day
after contamination; 3) thetrombocytophenia from 5th day after
contamination; 4) significantdrop of magnesium concentration on day 1st and
7th aftercontamination; 5) two significant drops of calcium concentrationon
day 1st and 3th after contamination; 6) significant drop ofphosphorus
concentration on day 7th, and 7) significant increasedof alkaline
phosphatase activity at the 1st day after injectionof 32P.
Keywords: radioactive phosphorus 32P, erytrocyte, hematocrit, hemoglobin, leukocyte, heterophils, eosinophils, lymphocyte, calcium, magnesium, iorganic phosphorus, alkaline phosphatase, blood, blood plasma, chicken.
- Type of paper
: Mentorship
Title: Effect of radioactive phosphorus 32P upon some
haematological and biochemical parameters in chicken blood.
Faculty: Veterinarski fakultet Zagreb
Date of defense: 06/18/93
Number of pages: 114
Author: Šimpraga Dr. Miljenko
Degree level: Ph.D.
- Type of paper
: Manuscript
Title: Effect of radioactive phosporus P-32 on some parameters in
blood plasma of chickens
- Authors:
- Šimpraga, Miljenko (104775)
- Kraljević, Petar (23266)
Language: engleski
Summary: The attempt was made to investigate the calcium, phsphorus
and magnesium concentration and alkaline pfosphatase activity in blood
plasma of chichens after injection of lethal amount (333 MBq/kg of body
weight) of radioactive phosphorus P-32. Obtained results have shown as
follows: 1) two significant drops of calcium concentration on day 1st and
3rd after contamination, 2) magnesium concentration was significantly
reduced on day 1st and 7th after contamination, 3) the phosphorus
concentration was significantly reduced on day 7th after contamination and
4) alkaline phosphatase activity was significantly increased at the
1st day after injection of P-32.
Keywords: chickens, P-32, contamination, calcium, phosphorus, magnesium, alkaline phosphatase, blood plasma