SVIBOR - Project code: 3-03-308


Strossmayerov trg 4, HR - 10000 ZAGREB
tel.: +385 1 459 44 44, fax: +385 1 459 44 69


SVIBOR - Collecting Data on Projects in Croatia

Project code: 3-03-308

Ethiopathology of systemic myopathias in animals

Main researcher: ČULJAK, KRIŽAN (8554)

Type of research: applied
Duration from: 03/01/91. to 03/01/94.

Papers on project (total): 7
Papers on project quoted in Current Contents: 1
Institution name: Veterinarski fakultet, Zagreb (53)

Summary: During 1991. we collected musculature from 50 fattening pigs originated from a larger farm. Histopathological examination of all 150 samples revealed dystrophic changes of various degree, but changes on blood vessels as well. According to those findings, in 1992 we took samples from another 50 fattening pigs. In muscles we diagnosed systemic myopathy, and in blood vessels chronic changes with thickening and hyperplasia of endothelium, fibroelastic proliferation and mononuclear cells infiltration. During 1992. we also collected musculature form lambs from a larger farm and individual breeders. In numerous muscles examined we diagnosed tipical Zenker's dystrophy, dystrophic calcification of gluteal muscles and Zenker's dystrophy of myocardium. Since the mortality rate in those lambs was high, we reccomended prophylactic application of Muvisel, Pliva, with good results. At the end of 1992 we took musculature from 50 fattening pigs, poorly fed on individual households of western Herzegovina. In that area pigs are poorly feed (some slops, brans and pasture) untill before slaughtering and they get some corn in October and November. Histopathological examination revealed nutritional deficiency, and since the summer 1993 was hot and dry, there was a lackage of pasture and mortality rate for fattening pigs was higher. We diagnosed systemic myopathy, although clinical veterinary diagnose was intoxication or bronchopneumonia. For the purposes of checking our postulation, at the end of 1993 we took samples of musculature from 50 fattening pigs from the same area. In 1993 we analysed sudden death of a large number of piglets in one farm. We found dystrophic changes in musculature and histopathology revealed infarcts in myocardium. We established E-vitamine deficiency and rough treatment (stress) at the time of weaning (i. e. at the time when mortality was high) as the cause of death. During the whole period we took the musculature and myocardium from fattening calves and bullocks. Our findings are going to be summarized in Master's thesis named "Pathological changes in myocardium of fattening calves". Biochemical serum analysis done on fattening bullocks revealed higher levels of NO2, and we plan to investigate those findings further. In 1994. special attention was pointed to the systemic myopathy of the young suckling goats and congenital goiter of the same animals. Both diseases increases in frequency especially in areas i which until now they did not beeen detected.

Keywords: myopathy, Zenker's dystrophy, musculature, pigs, piglets, lambs, calves, bullocks

Research goals: The goal is revealing the ethiology and define ethiological factors of systemic myopathys, through histopathological examinations of skeletal muscles and myocardium of animals from various districts, with various clinical status and zoohygienic treatment. Through the correction of mentioned ethiological factors we want to enable the production of animal products of high standards. That way we help maintaining the health of population and minimalize mortality rate in farm animals as well as those held on individual hauseholds.


  1. Name of institution: Svinjogojska farma PIP Sljeme, Sesvete
    Type of institution: State institute
    City: 10000 - Zagreb, Croatia

  2. Name of institution: Svinjogojska farma PIK Vrbovec
    Type of institution: State institute
    City: 43216 - Vrbovec, Hrvatska

  3. Name of institution: Hrvatski veterinarski institut - Centar za peradarstvo
    Type of institution: University/Faculty
    City: 10000 - Zagreb, Croatia

  4. Name of institution: "Agrolaguna" - farma ovaca
    Type of institution: Non-profit
    City: 52440 - Poreč, Croatia

  5. Name of institution: PIK Kutjevo
    Type of institution: State institute
    City: 55340 - Kutjevo, Hrvatska

Other information about the project.
MZT Croatian language SVIBOR Alphabetic list Sorted on project code Sorted on institutions Search help
Ministry of
Science and
Sorted on
project code
Sorted on
Search Help

Last update: 09/13/95