- Type of paper
: Paper in book
Title: Disturbances of metabolism, cell injury and death -
processes of regression.
- Authors:
- Grabarević, Željko (14604)
- Editors
- Čuljak, Križan (8554)
Publisher: Horetzky, nakladničko poduzeće
Year: 1993
Pages: from 65 to 107
Number of references: 31
Language: hrvatski
Summary: In this chapter, dystrophic processes which include
generalconsiderations, disturbances of protein, lipid and
glicogenmetabolism are described. Beside that, intracellularacummulations,
disturbences of pigmentation and cell death arealso noted.
Other: Ovdje se radi o poglavlju u studentskom uđžbeniku koje
nemaizrazito znanstveni karakter. Međutim, navedeni su svi relevantnii
nedvojbeni podaci (podaci koji nisu znanstveno sporni)neophodni za
razumijevanje teksta i moderan pristup patologiji.Projekt je svakako
pridonio kvalitetnijem pristupu informacijamai obradi teksta i ilustracija.
- Type of paper
: Paper in book
Title: Inflammation
- Authors:
- Grabarević, Željko (14604)
- Editors
- Čuljak, Križan (8554)
Publisher: Horetzky, nakladničko poduzeće
Year: 1993
Pages: from 127 to 155
Number of references: 22
Language: hrvatski
Summary: In this chapter, ethiopathogenetic mechanisms of the
begining,development and ending of the inflammation, together withdeviding
of the inflammation according to its character andduration are described.
Main characteristics of the, so called,specific inflammation, are also
mentioned.
Other: Ovdje vrijede iste napomene kao za prethodno poglavlje, tj.
da seradi o moderno napisanom studentskom udžbeniku, čije pisanje je
umnogome olakšano sredstvima znanstvenog projekta.
- Type of paper
: Paper in book
Title: Report by the international commission of impartial
observers and veterinary officers on destroying the lipizzaner in Lipik.
- Authors:
- Grabarević, Željko (14604)
- Salamon, Davor
- Stephen, George
- Carding, Noel
- Franetič, Andrej
- Hrastnik, Zlatko
- Salamon, Davor
- Editors
- Kraljević, Petar
Publisher: Veterinarski fakultet Sveučilišta u Zagrebu
ISBN: 953-6062-01-1
Year: 1993
Pages: from 83 to 106
Language: engleski
Summary: In respect of the scantiness of information and
questionable facts associated with what was clearly revealed the commission
can only state that the loss of horses at Lipik was as a direct result of
the outbreak of hostilities and that since in their opinion the manner of
fighting in and around Lipik was so intense it is clear that many horses
would have suffered directly or indirectly and/or would have been injured
or killed.
- Type of paper
: Paper in journal
Title: Morphological aspects of restraint stress induced lesions
in rats
- Authors:
- Grabarević, Željko (14604)
- Seiwerth, Sven (149676)
- Sikirić, Predrag (117454)
- Artuković, Branka (139800)
- Tišljar, Marina (130726)
- Džaja, Petar (188481)
Journal: Veterinarski arhiv (suplement)
ISSN: 0372-5480
Volume: 62
Year: 1992
Pages: from 53 to 58
Number of references: 9
Language: engleski
Summary: Pathohistological changes in the stomach, liver, heart,
testesand spleen developed during the restraint stress were studied.The
animals were Wistar albino rats restrained for 24 and 48hours. Exept for
the liver, all organs showed more severe lesionsafter 48 hours. In the
stomach bleeding mucosal defects were theprinciple finding, in the heart a
cloudy swelling and hyalinedegeneration, in the liver a fatty change, in
the spleen adepletion of the follicle "mantle zone", and in the testes
areduction of the germinal epithelium. The role of circulatorydisorders and
the influence of free radicals in the pathogenesisof the lesions are
discussed.
Keywords: pathohistological changes, restraint stress, rats
- Type of paper
: Paper in journal
Title: The extent of inflammatory lesions in colon of NMRI mice
induced with 2,4-dinitrofluorbenzene. The influence of different
concentrations and previous sensitization.
- Authors:
- Banić, Marko (164816)
- Brkić, Tomislav (136556)
- Anić, Branimir (140514)
- Grabarević, Željko (14604)
- Rotkvić, Ivo (127672)
- Duvnjak, Marko (138233)
- Marić, Stela
- Artuković, Branka (139800)
- Troskot, Branko (117465)
Journal: Veterinarski arhiv (suplement)
ISSN: 0372-5480
Volume: 62
Year: 1992
Pages: from 1 to 7
Number of references: 10
Language: engleski
Summary: The aim of the study was to provoke inflammatory lesions in
thecolon of NMRI mice using 2,4-dinitrofluorbenzene (DNFB) and
todemonstrate the influence of different concentrations of locallyapplied
DNFB, as well as the previous skin sensitization on theextent of induced
lesions. The animals in the experimental groupswere treated with the rectal
enema of 0.1/0.2/0.5/1.0 % DNFBsolutions and with the rectal enema of 0.2 %
DNFB solution afterprevious skin sensitization respectively. The animals in
thecontrol group received the rectal enema with the equivolume ofphosphate
buffered saline. Edema, hemorrhage, ulcerations andlymphoid hyperplasia in
the lamina propria and submucosa weremostly pronounced in the group treated
with the rectal enema of0.5% DNFB solution, and the group of animals skin
sensitizedprior to receiving the rectal enema of 0.2 % DNFB
solution(P<0.01). Colonic specimens of animals in the control grouprevealed
no changes, compared to the colon of healthy mice. Theresults suggest the
importance of immunogenic characteristics ofDNFB, as well as its
inflammatory and irritant properties whenapplied to mucosal surfaces.
Keywords: Inflammatory Bowel Disease, 2,4-dinitrofluorbenzene (DNFB), sensitization, experimental model, NMRI mice
- Type of paper
: Paper in journal
Title: Subacute toxicity of T-2 toxine and DAS in broiler chicks.
- Authors:
- Grabarević, Željko (14604)
- Nemanič, Ankica (33271)
- Jagić, Vjekoslav (101645)
- Tišljar, Marina (130726)
- Artuković, Branka (139800)
- Džaja, Petar (188481)
- Čuljak, Križan (8554)
- Rinck, Ivan
Journal: Veterinarski arhiv
Number: 6
ISSN: 0372-5480
Volume: 62
Year: 1992
Pages: from 317 to 324
Number of references: 17
Language: engleski
Summary: Three groups containing 30 one-day old Hybro broiler chiks
eachwere used in the experiment. Group K was control, group Breceived 0.5
ppm of T-2 toxin during the second and third week(14 days) of fattening,
and group C was treated with a same doseand in the same period with
diacetoxyscipenol (DAS). Five animalsfrom each group were sacrificed at the
end of each week. Theduration of the experiment was six weeks.
Pathohistologicalfindings revealed severe liver changes characterised by
fattychanges and signs of necrosis in both treated groups of chicks,kidney
tubular degeneration, duodenal villous atrophy andperivascular cerebral
edema. Enzyme activities (AST, ALT, CPK,LDH, alkaline phosphatase) were
inconsistently changed but thebilirubine level in the chiks treated with
DAS was significantlyraised.
Keywords: T-2 toxin, diacetoxyscirpenol (DAS), subacute effects, broiler chicks
- Type of paper
: Paper in journal
Title: A preliminary report on dopamine cytoprotection: an in
vivo and in vitro study.
- Authors:
- Sikirić, Predrag (117454)
- Rotkvić, Ivo (127672)
- Miše, Stjepan (102751)
- Seiwerth, Sven (149676)
- Grabarević, Željko (14604)
- Jagić, Vjekoslav (101645)
- Petek, Marijan (67993)
- Suchanek, Ernest (98740)
- Ručman, Rudolf
- Đermanović, Zoran
- Mikulandra, Simon (178645)
- Duvnjak, Marko (138233)
- Brkić, Tomislav (136556)
- Dodig, Milan (178511)
- Banić, Marko (164816)
- Hernandez, Danijel
Journal: Journal of Experimental and Clinical Gastroenterology. An
International Journal
Number: 2
ISSN: 0353-9245
Volume: 1
Year: 1991
Pages: from 133 to 137
Number of references: 28
Language: engleski
Summary: The protective effect of dopamina was further investigated
bothin vivo and in vitro with the dopamine agents bromocriptine
andamantadine in the presence of PGs-synthesis blockade withindomethacin in
6 h restraint stressed rats. The dopamine agentsinduced gastric protection
regardless of pretreatment withindomethacin. The in vitro studies revealed
that indomethacin,unlike unlabeled dopamine, did not inhibit the binding
of3H-dopamine to both rat gastric mucosa and muscle. The results ofthis
study indicate that bromocriptine and amantadine preventstress gastric
lesions independent of endogenous prostaglandins.
Keywords: Bromcriptine, amantadine, indomethacin, protection, endogenous dopamine and prostaglandins, dopamine cytoprotection
- Type of paper
: Paper in journal
Title: Short-time pylorus-ligation method
- Authors:
- Sikirić, Predrag (117454)
- Rotkvić, Ivo (127672)
- Seiwerth, Sven (149676)
- Grabarević, Željko (14604)
- Jagić, Vjekoslav (101645)
- Duvnjak, Marko (138233)
- Artuković, Branka (139800)
Journal: Journal of Experimental and Clinical Gastroenterology. An
International Journal
Number: 4
ISSN: 0353-9245
Volume: 1
Year: 1992
Pages: from 343 to 348
Number of references: 18
Language: engleski
Summary: To date there is no report on the effect of the short
timepyloric ligature (e.g. 1 min) on experimental gastric lesions. Inthis
way, the unpleasant limiting factors (such as forestomachlesions, excessive
gastric juice accumulation, unphysiologicaldistension of stomach) known
after conventional period ofligature (e.g. hours) were fully avoided. In
addition to completepyloric occlusion, anaesthesia, abdominal incision
andloose pyloric ligature were tested as sham procedures. Wedemonstrated
that complete pyloric occlusion even for shortperiod (e.g. 15 min)
inevitably produced very stronghaemorrhagic lesions ("stress ulcers")
(microscopically appearingas erosions, in addition to lamina propria
permeated by red bloodcells and regularly compressed empty stomach blood
vessels).Moreover, some minor lesions were found already after
looseligature. Since pyloric ligation firstly damages serosal stomachside
and mucosal resistance was found to be extremely vulnerableto serosal
injuries, it was suggested that from serosal sideproduced by
touching/handling of stomach ischaemicmicrocirculatory disorders even
without intraluminal processes)are responsible for described brief lesions
development.
Keywords: short time-pylorus ligation, sham procedures, serosal side, ischaemia, haemorrhagic gastric lesions
- Type of paper
: Paper in journal
Title: The 2,4-dinitrofluorbenzene induced inflammatory lesions
in colon of NMRI mice: influence of previous sensitization on mononuclear
cell infiltration
- Authors:
- Banić, Marko (164816)
- Brkić, Tomislav (136556)
- Anić, Branimir (140514)
- Grabarević, Željko (14604)
- Rotkvić, Ivo (127672)
- Duvnjak, Marko (138233)
- Džaja, Petar (188481)
- Marić, Stela
- Troskot, Branko (117465)
Journal: Acta medica Croatica
Number: 4
ISSN: 1330-0164
Volume: 46
Year: 1992
Pages: from 205 to 208
Number of references: 12
Language: engleski
Summary: The aim of this study was to obtain inflammatory lesions in
colonof NMRI mice and to demonstrate the influence of previoussensitization
with 2,4-dinitrofluorbenzene (DNFB) on the extentof mononuclear cell
infiltration within lamina propria andsubmucosa after the challenge enema
with DNFB. The animals inexpeerimental group were sensitized prior to
receiving thechallenge enema into the lumen of colon. The animals in
controlgroup received only the challenge enema. During follow-up
period(24-72 hours after challenge) edema, haemorrhage and ulcerationwere
observed in colon of experimental group of animals and to alesser extent in
control group. The significant difference inmononuclear cell infiltration
of lamina propria and submucosabetween experimental and control group was
found on 24 hours, and48-72 hours after DNFB edema, respectively (p<0.01).
Inconclusion, our results demonstrated the efficacy
of2,4-dinitrofluorbenzene in inducing the colonic lesions in miceshowing
the great importance of previous sensitization accordingto the mononuclear
cell infiltration of colonic lamina propriaand submucosa.
Keywords: 2,4-dinitrofluorbenzene (DNFB), experimental model, inflammatory bowel disease, NMRI mice, sensitization
- Type of paper
: Paper in journal
Title: The first finding of "going light" syndrome in pet birds
in Croatia.
- Authors:
- Tišljar, Marina (130726)
- Grabarević, Željko (14604)
- Artuković, Branka (139800)
- Džaja, Petar (188481)
Journal: Veterinarski arhiv
Number: 1
ISSN: 0372-5480
Volume: 63
Year: 1993
Pages: from 29 to 36
Number of references: 17
Language: engleski
Summary: Proventriculitis with subsequent proventricular ulcers
followedby gizzard erosions and melena were found with an incidence of30%
as a cause of death during necropsies of different species of34 pet birds
in the last 18 months. The examined birds wereextremely cachectic and
exicotic. In all proventriculi a greatamount of whitish mucous masses and a
rather thinproventriculus-gizzard junction wall with discrete
haemorrhagesin its mucosa were found. Microscopically examined
gram-stainedproventricular mucosa smears revealed rod shaped,
gram-positive,2-40 micron large organisms in 80% of birds with
proventricularlesions. Considering the anamnestic data,
pathomorphological,histological and cytological findings including the
presentknowledge of the cause of proventriculitis associated with
"goinglight syndrome" in budgerigars and some other species ofpet-birds,
the organisms were identified as mega-bacteria.
Keywords: mega-bacteria, goinght light syndrome, proventriculitis, pet birds, budgerigars
- Type of paper
: Paper in journal
Title: Is dopamine one of the endogenous antiulcer factors?
- Authors:
- Sikirić, Predrag (117454)
- Seiwerth, Sven (149676)
- Grabarević, Željko (14604)
- Rotkvić, Ivo (127672)
- Petek, Marijan (67993)
- Duvnjak, Marko (138233)
- Đačić, Sanja (177464)
- Šimičević, Velimir (178660)
Journal: Journal of Experimental and Clinical Gastroenterology. An
International Journal
Number: 4
ISSN: 0353-9245
Volume: 2
Year: 1992
Pages: from 242 to 249
Number of references: 90
Language: engleski
Summary: Dopamine acts probably as physiological endogenous
antiulcer factor. Therefore, it seems that the introduction of dopamine
agonists in the treatment of ulcer disease should be a logical way to a
more etiologic therapy of ulcer disease.
Keywords: dopamine, etiologic therapy, ulcer disease
- Type of paper
: Ph.D.
Title: Immunosuppressive and toxic characteristics of the
Fusarium fungusisolated from the poultry forage.
Faculty: Veterinarski fakultet Sveučilište u Zagrebu
Author: NEMANIČ ANKICA
Date of defense: 07/07/92
Language: hrvatski
Number of pages: 164
Summary:
Effects of T-2 toxin (0.5 mg/kg food) on broiler chicks were investigated.
Chicks were randomly divided and placed in four groups of 30 chicks per
each group. Group A was control, in group B chicks were treated with toxin
during second and third week of life, in group C broilers were treated
during fourth and fifth week, and in group D animals received mycotoxin
during all six weeks of fattening. All chicks were vaccinated against
NewCastle disease on the day 14. Chickens were weighed every week and bllod
was taken for serologic examinations and electrophoresis. Thymus, spleen,
bursa of Fabricius and caecal tonsils were histologically examined.
Chickens in group D had worsened weight gain compared to the controls.
Degeneration and lymphoid atrophy were noted in spleen, thymus and bursa of
Fabricius. T-2 toxin was not found to cause inhibition of the specific HI
antibody formation. Prealbumin was elevated in the group C and
alphaglobulin in the group B compared to the control animals.
Keywords: T-2 toxin, NewCastle disease, blood proteins, patohistology of the immunocompetent organs, weight gain, chickens
- Type of paper
: Ph.D.
Title: Forensic evaluation of the gizzard erosion in broiler
chicks
Faculty: Veterinarski fakultet Sveučilište u Zagrebu
Author: DŽAJA PETAR
Date of defense: 12/16/94
Language: hrvatski
Number of pages: 135
Summary: The effects of various doses of histamine, L-NAME and
L-arginine on healthy chicks were axamined as of histamine, nisatidine,
dopamine agonist bromocriptine, dopamine antagonist domperidone, L-NAME and
L-arginine on the chicky stressed by water-immersion-stress. Besides, the
immunological effects (antibody level after vaccination against New Castle
disease and the efficiency of fattening (food conversion, weight gain,
slaughter-house weight and relative weights of stomachs) in fattened-up
chicks treated once with histamine and stressed ones were examined. The
results show that 10mg/kg of histamine causes gizzard erosions and
increases the ALT activity. In stressed animals bromocriptine decreases and
L-arginine increases gizzard erosions. Converion of food was increased in
stressed animals and weight gain was decreased in both tested groups. In
relation to the control animals slaughter-house weights were significantla
decreased in the stressed and in histamine treated animals. Forensic
evaluation showed that this disease represent concelaed and considerable
chick disease.
Keywords: gizzard erosion, histamine, dopamine, nitric oxide, antibody titer, weight gain, food conversion, sloughter-house weight, forensic evaluation, chickens
- Type of paper
: Mentorship
Title: The dopamine drugs effects on inflammatory bowel disease
induced by 2,4-dinitrofluorbenzene in BALB/c mice.
Faculty: Veterinarski fakultet Sveučilište u Zagrebu
Mentor: GRABAREVIĆ ŽELJKO
Date of defense: 02/09/95
Number of pages: 115
Author: Herak-Perković dipl. vet., mr.sci Vlasta
Degree level: M.A.
- Type of paper
: Mentorship
Title: Forensic evaluation of the gizzard erosion in broiler
chicks.
Faculty: Veterinarski fakultet Sveučilište u Zagrebu
Mentor: GRABAREVIĆ ŽELJKO
Date of defense: 12/16/94
Number of pages: 135
Author: Džaja Petar
Degree level: Ph.D.
- Type of paper
: Mentorship
Title: AgNOR method and TNM classification in mammary tumours
diagnostics in bitches.
Faculty: Veterinarski fakultet Sveučilište u Zagrebu
Mentor: GRABAREVIĆ ŽELJKO
Date of defense: 10/06/95
Number of pages: 95
Author: Bratulić dipl. vet. Mirna
Degree level: M.A.
