SVIBOR - Papers quoted in CC - project code: 3-03-355

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Papers quoted in Current Contents on project 3-03-355

Quoted papers: 3
Other papers: 11
Total: 14

Title:

Authors:: Gojmerac, Tihomira; Mitak, Mario; Kartal, Božica; Žurić, Marijan (118411); Ćurić, Stipica (108013)

Journal: Journal of Applied Toxicology
Number: 3
ISSN: 0260-437X
Volume: 15
Year: 1995
Pages: from 223 to 236
Number of references: 24
Language: engleski
Summary: Biochemical and histopathological parameters of the hepatic function were used to quantify the hepatotoxic effects of atrazine in female pigs undergoing intensive breeding.Female pigs(cross-bred Swedish and German landrace) received 2 mg atrazine per kg body wt. in feed daily during 19 days of the oestrous cycle.The last treatment day corresponded to day -3 of the onset of the next expected oestrus.Blood samples were collected three times daily at 3-h intervals on the first four post-treatment days.Serum activities of gamma-glutamyltransferase (GGT),alanine aminotransferase (ALT),aspartate aminotransferase (AST) and alkaline phosphatase (AP) were determined.Serum activity of GGT was significantly increased throughout the four post-treatment days.In comparison with the control values,a slight but not significant decrease was observed in the serum activities of ALT,AST and AP.Histopathological examination of the liver of exposed pigs showed mild centrolobular parenchymatous degeneration.Interstitial connective tissue proliferation resulted in narrow and irregular bile canaliculi.
Keywords: s-triazine herbicide,atrazine,hepatic function,hepatotoxicity,pigs,gilts

Title:

Authors:: Gojmerac, Tihomira; Kartal, Božica; Rajković-Janje, Ranka (40074); Bilandžić, Nina; Roić, Besi (137105)

Journal: Bulletin of Environmental Contamination and Toxicology
Number: 2
ISSN: 0007-4861
Volume: 16
Year: 1996
Number of references: 15
Language: engleski
Summary: In our study,results of the atrazine analysis in the samples of drinking water from the Dubravica and Sljeme pig-breedingfarms,were presented.We used of enzymelinked immunosorbent assay (ELISA) and high performance liquid chromatography (HPLC) for this one-year seasonal monitoring of atrazine. Atrazine was found in 75 % of the samples of drinking water collected from the Dubravica pig-breeding farm.During early spring(April),the concentration of atrazine varied from 0,93-2,3 ug/L. Even 50 % of the samples of drinking water collected from the Sljeme pig-breeding farm were atrazine-positive.Throughout the monitoring period,the concentration of atrazine varied from 0.15-0.29 ug/L.In all samples,the concentration of atrazine exceeded the maximal tolerable concentration of 0.1 ug/L set by the European Communities for single pesticides in water intended for human consumption and the respective by-low of the Republic of Croatia (Official Gazette of the Republic of Croatia,1994),pointing to the need for regular analytical control of sources of drinking water for this contaminant. Our results showed a very good correlation (r=0.98) of the ELISAwith the conventional HPLC analysis of samples of drinking water for atrazine.
Keywords: s-triazine herbicides,atrazine,analytical method for determination,ELISA,HPLC

Title:

Authors:: Gojmerac, Tihomira; Kartal, Božica; Cvetnić, Željko (173333); Ćurić, Stipica (108013); Žurić, Marijan (118411)

Journal: Toxicology Letters
ISSN: 0378-4274
Number of references: 21
Language: engleski
Summary: Biochemical and histopathological parameters of the ovarian function wereobserved to assess the toxic effect of low dose of atrazine,an s-triazine herbicide,in female pigs undergoing intensive breeding.Cross-bred female pigs between Swedish and German landrace received 2 mg atrazine per kg body weight in feed daily during 19 days of their oestrous cycle.The last treatment day corresponded to day -4 of the onset of the next expected oestrus,Blood samples were collected three times daily at 3-h intervals on the first five post-treatment days.Serum 17á-oestradiol (17á-E) and progesterone (P) concentration were determined.A significantly higher serum P and significantly lower serum 17á-E concentration were recorded 48 h and 24 h before onset of the next expected oestrus in atrazine-treated pigs,as comparated to intact pigs.The next expected oestrus failed to occur,but no other adverse clinical reactions associated with the treatment were recorded.Histopathological examination of the ovaries of treated pigs indicated multiple ovarian follicular cysts and persistence of corpus luteum.Biochemical and histopathological findings showed that subacute exposure of female pigs to low dose of atrazine prolonged their oestrouscycle.
Keywords: s-triazine herbicides, atrazine,toxicology,reproduction,ovarian disorders,oestrus,female pigs,gilts


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