DEVELOPMENT OF (BIO)SENSORS AND COMPUTERIZED INSTRUMENTATION
Main researcher
: GRABARIĆ, BOŽIDAR (14042) Assistants
MURKOVIĆ, IVANA (178963)
MILARDOVIĆ, STJEPAN (154444)
TKALČEC, MIHAEL (49616)
BOROVNJAK-ZLATARIĆ, BISERKA (4673)
SIPOS, LASZLO (43303)
KRUHAK, IVAN (24133)
Type of research: basic Duration from: 01/01/91. to 12/15/95. Papers on project (total): 45
Papers on project quoted in Current Contents: 8
Institution name: Fakultet kemijskog inženjerstva i tehnologije, Zagreb (125) Department/Institute: Department of General and Inorganic Chemistry Address: Marulićev trg 19 City: 10000 - Zagreb, Croatia
Communication
Phone: 385 (0)1 440 241
Fax: 385 (0)1 4550 725
Phone: ++34 3 402 1277 (do 1.10.96.)
Fax: ++34 3 402 1233 (do 1.10.96.)
E-mail: voltamp@quimio.qui.ub.es ( " )
Fax: 385 (0)1 443 647
Phone: 385 (0)1 443 647
Summary: Development and applications of chemical sensors is one of
the most interdisciplinary research field. It combines the knowledge of
chemistry, physics and biology (fisical chemistry, biochemistry and
biophysics) with knowledge of matematical and statistical (chemometrical)
methods and with engineering, technical and technological production. In
this project chemical reactions have been investigated of potential
interests for electrochemical and optochemical sensoring. Chemometrical
methods for sensoring signals evaluation and deconvolutions have been
developed. Principles of computerized sensoring measurements have also
been investigated. Techologies for productions of some dozen ion selective
electrodes have been developed, and using their modification the analyte
range can be extended and/or selectivity and sensitivity can be improved.
Research goals: The goals of the investigation in this project are
more ambitious then is the financial support given: 1. Updating of the
hardware and software for computerized systems developed within the frame
of the project research in the past period. 2. Hardware and software
development of the computerized hyphenated techniques, e.g.
electrochemical-spectrometric-chromatographic. 3. Development of
voltammetric and amperometric sensors (global and specific) for
determination of different ionic and molecular species. 4. Special
attention will be payed in sensors and instrumentation miniaturization
envisaging in the future a single chip sensig unit. 5. Development of the
technology for membrane production in order to investigate the properties
of different ionophores and membrane modifications. Investigation of
microlide antibiotics and their ionophoric properties (cooperation with
dr. S. Mutak from "Pliva" Zagreb, started at the end of 1993). 6.
Specialize in the field of biochemistry and biochemical engineering in
order to develop biosensors for monitoring of the environment (air, water,
soil), food and oder biochemical productions. Cooperation with Prof. dr.
N. Košarić. J. Velikonja decided not to return from Canada! 7. Cooperation
with Prof. dr. O Wolfbeis in the field of optochemical sensing (Started at
the end of 1993. with Ivana Murković doing her Ph.D. thesis.). 8.
Development and application of chemometrical techniques on electrochemical
data. Cooperation with Prof.dr. M. Esteban and Prof.dr. R. Tauler started
at the end of 1993 with Prof.dr. B.S. Grabarić as visiting profesor in
University of Barcelona. 9. To form a nucleus of young investigators on
chemical sensing in order to promote in the future a Croatian Center for
Development and Applications of Chemical Sensors.
COOPERATION - INSTITUTIONS
Name of institution
: The University of Western Ontario, Faculty
of Engineering Science, Department of Chemical and Biochemical Engineering Type of institution: University/Faculty Type of cooperation: Occasional exchange of experts City: N6A 5B9 - London, Ontario, Canada
Name of institution
: Universitat de Barcelona, Facultat de
Quimica, Departament de Quimica Analitica Type of institution: University/Faculty Type of cooperation: Occasional exchange of experts City: 08028 - Barcelona, Španjolska
Name of institution
: Pliva, Istraživanje i razvoj Type of institution: State institute Type of cooperation: Occasional exchange of information City: 10000 - Zagreb, Croatia
Name of institution
: Karl-Franzens Universitat, Institut fur
Organische Chmie, Analitische Division Type of institution: University/Faculty Type of cooperation: Occasional exchange of experts City: 8010 - Graz, Austrija
Name of institution
: Universitat Autonoma de Barcelona Type of institution: University/Faculty Type of cooperation: Occasional exchange of experts City: Bellaterra, Španjolska
OTHER ACHIEVEMENTS
Name
: Ionsko osjetljive elektrode Type of achievement: Instrumentation Authors: S. Milardović, I. Kruhak, B.S. Grabarić
Name
: Programski paket ONLINE za vodjenje, prikupljanje podataka
i obradu podataka Type of achievement: Teaching aids and educatio Authors: M. Tkalčec, T. Ferber
Name
: Programski paket SENSIG u MATLAB-u za obradu
eksperimentalnih podataka Type of achievement: Teaching aids and educatio Authors: B.S. Grabarić Other information about the project.