SVIBOR - Project code: 3-01-059

MINISTRY OF SCIENCE AND TECHNOLOGY

Strossmayerov trg 4, HR - 10000 ZAGREB
tel.: +385 1 459 44 44, fax: +385 1 459 44 69
E-mail: ured@znanost.hr

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Project code: 3-01-059


Follow-up of blood flow during therapy of the cancer of the cervix of the uterus and breast


Main researcher: BREYER, BRANKO (61770)



Assistants
Type of research: applied
Duration from: 01/01/91. to 01/01/95.

Papers on project (total): 28
Papers on project quoted in Current Contents: 2
Institution name: Medicinski fakultet, Zagreb (108)
Department/Institute: Gynaecological Cancer Centre, Department of Obstetrics and Gynaecology
Address: Petrova 13, 41000 Zagreb
City: 10000 - Zagreb, Croatia
Communication
E-mail: bbreyer@maja.zems.hr
E-mail: branko.breyer@fer.hr
Phone: 385 (0)1 175092

Summary: Blood flow characteristics were measured in patients with hystologically proven cervical cancer and compared to normal values. Flow parameters were derived by pulsed and colour Doppler ultrasound. The results show a significant difference in the mean values of resistance index and pulsatility index between the diseased patients and controls. Ony patients who were treated by radiation, chemotherapy or combination thereof have been considered so that a five years follow-up is possible. The specificity is unsuficient for screening purposes. The method is not sufficiently sensitive for breast cancer evaluation.

Keywords: ultrasound, Doppler, colour Doppler, cancer of the uterine cervix, cancer, pulsatility index, resistance index, breast, breast cancer, radiotherapy, chemotherapy, cancer follow-up

Research goals: The aim of the research is to develop a method for evaluation of the success of radiotherapy or chemotherapy of cervical cancer. Early detection of unsufficient radicality or recurence of the disease would improve the chances for the success of the treatment. We expect to see that the blood flow indices return to normal in successfully treated patients. The time scale of the research (5 years) is determined by the speed of the cancer growth and rules of vital statistics.

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Last update: 10/09/95
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