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Summary: Today, more and more, with increasing frequency,
allergicdiseases afflict children's health even at their early age and
ascronic diseases they affect 15-20% of the children population.
Since the correlation between the increased IgE concentrationsand atopy is
very good, we consider the creening of IgE fromneonates' cord venous blood,
at birth, the most important riskfactor according to which it is possible
to predict appearance ofallergy in their cearly childhood.
The studies carried out in Swedenn, Kjellman and all, reveal that80.2% of
the children whose IgE were increased at birth, get someform of allergic
disease before they reach six. Only 3.4% of thechildren with increased IgE
concentrations at neonatal age do notget any form of allercig disease at
their older age. The samegroup of authors also state that by observing
allergy appearancein children, it has been found out that 93.7% of the sick
childrehad increased IgE concentrations at birth.
Therefore, we think that it colud be a successful preventiveprogramme for
early detection of allergic diseases in childrenand at the same it has its
economical justification since itenables the society to save up. Namely,
the total IgE screeningexpenses in neonatal period are considerably lower
than theexpenses needed for medical treatment of the children
whochronically suffer from allergic diseases (for example: bronchialasthma
Research goals: Our research of IgE concentrations in nweborns is
aiming at: 1. predictiong of allergic disorders as early as possible,
namely, carrying out selection of future allergy - sufferers. There is a
certaion knowledge which helps us to prove that IgE taken from the
newborns' code vein can serve in predicting of allergic disease
development: - fetus is capable to synthesize IgE quite
independently already in the 11th weed of its intrauterinal life; -
mother's IgE do not pass through placenta; - there is a very good
clinical correlation between increased IgE concentration and atopy. 2.
Timely noticing of causative factors and carrying out of measures by which
appearance of clinical disorders could be postponed; 3. Duly and timely
medical treatment of the ocurred difficulties. 4. Enabling in this
way certain economical savings and lower expenses which society has for
medical treatment of children who suffer from cronic allegic diseases.
: Polinoza i specifična hiposenzibilizacija u djece
(magistarski rad) Type of achievement: Studies of conduct Authors: Muhvić-Ostojić Đurđica, (mentor: Vekarić Semida) Other information about the project.