SVIBOR - Project code: 3-01-346


Strossmayerov trg 4, HR - 10000 ZAGREB
tel.: +385 1 459 44 44, fax: +385 1 459 44 69


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Project code: 3-01-346

Influence of exercise on the hyperkinetic circulation

Main researcher: KARNER, IVAN (103355)

Type of research: applied
Duration from: 06/01/91. to 06/01/96.

Papers on project (total): 13
Papers on project quoted in Current Contents: 1
Institution name: Bolnica, Znanstvena jedinica za klinička medicinska istraživanja, Osijek (127)
Department/Institute: Clinical hospital Osijek Department for nuclear medicine
Address: Josipa Huttlera 4
City: 31000 - Osijek, Croatia
Phone: 385 (0)54 55-52-22 (600,602)
Fax: 385 (0)54 55-11-11

Summary: Examination of the features of the hyperkinetic circulation of the hyperkinetic heart syndrome using accepted and evaluated procedures in nuclear medicine. Comparison of the results obtained in the submitted study to those of the previous study (hyperkinetic circulation in hyperthyreoidism). A selected group of female patients ranging in age from 20 to 40 years will be examined. The following parameters will be examined: left ventricular global ejection fraction, duration of sistola, peak ejection rate, duration of diastola, peak filling rate, stroke volume and cardiac output, blood volume, effective renal plasma flow, plasma renin activity, peripheral venous blood aldosteron level. Systolic and diastolic blood pressure, heart rate and double product will be determined, too. The parameters mentioned will be determined at rest and after the cycloergometric load of 50 to 75 W during 10 minutes.

Keywords: physical exercise, hyperkinetic heart syndrome, hyperthyreoidismus

Research goals: Determination of the features of the hyperkinetic heart syndrome using the affirmed methods in nuclear medicine, examination of the functional response of the cardiovascular system and renal function by this clinical entity at rest and after controled exercise load. To emphasize the resemblance and the differences (if there are some) between the hyperkinetic heart syndrome and the hyperkinetic circulation by hyperthyreoidism (both classified as disturbances characterized by so called kinetic circulation) that came out from the comparison between the results obtained in the submitted study and those of the previous study (florid hyperthyreoidism). There was no relevant similar data found in the available literature, i.e. there was no investigation concerning the above mentioned features by a selected group of patients with hyperkinetic heart syndrome that was numerous enough for relevant conclusions.

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Last update: 10/11/95